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TAOK1: Clinical significance & Overview

Serine/threonine-protein kinase TAO1 is an enzyme that in humans is encoded by the TAOK1 gene.

Language: English [EN]
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TAOK1 topic overview

The analysis highlights Clinical significance and Overview as prominent areas in the source structure around TAOK1.

Related topics
3
Source areas
2
Connected nodes
5
Extracted relationships
107
Concept neighborhoods
5
Bridge connections
5

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 2 topics
Clinical significance · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.1
Aliases
TAOK1, KFC-B, MAP3K16, MARKK, PSK-2, PSK2, TAO1, hKFC-B, hTAO kinase 1, DDIB
Band
17q11.2 · 11|11 B5
Bgee
corpus callosum · globus pallidus · internal globus pallidus · ventral tegmental area · subthalamic nucleus
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How TAOK1 connects Entity context

The extracted context around TAOK1 shows recurring relationship patterns in the source. For example, TAOK1 → activation of protein kinase activity, alpha-tubulin binding, apoptotic process, ATP binding, beta-tubulin binding, cellular response to DNA damage stimulus, cytoplasm, cytosol, DNA repair, execution phase of apoptosis, extracellular exosome, kinase activity, MAP kinase kinase kinase activity, MAPK cascade, microtubule cytoskeleton, microtubule cytoskeleton organization, mitotic G2 DNA damage checkpoint signaling, negative regulation of microtubule depolymerization, nervous system development, neuron cellular homeostasis Another extracted example is TAOK1 → amygdala, anterior amygdaloid area, corpus callosum, external globus pallidus, globus pallidus, habenula, inferior colliculi, inferior ganglion of vagus nerve, internal globus pallidus, lateral geniculate nucleus, lateral septal nucleus, mammillary body, olfactory tubercle, pars compacta, pons, subthalamic nucleus, sural nerve, ventral tegmental area, ventromedial nucleus. Use these groups to spot repeated connection types before inspecting the individual relationships.

TAOK1

Top relations

Gene ontology · 45
TAOK1 → activation of protein kinase activity, alpha-tubulin binding, apoptotic process, ATP binding, beta-tubulin binding, cellular response to DNA damage stimulus, cytoplasm, cytosol, DNA repair, execution phase of apoptosis, extracellular exosome, kinase activity, MAP kinase kinase kinase activity, MAPK cascade, microtubule cytoskeleton, microtubule cytoskeleton organization, mitotic G2 DNA damage checkpoint signaling, negative regulation of microtubule depolymerization, nervous system development, neuron cellular homeostasis
Bgee · 19
TAOK1 → amygdala, anterior amygdaloid area, corpus callosum, external globus pallidus, globus pallidus, habenula, inferior colliculi, inferior ganglion of vagus nerve, internal globus pallidus, lateral geniculate nucleus, lateral septal nucleus, mammillary body, olfactory tubercle, pars compacta, pons, subthalamic nucleus, sural nerve, ventral tegmental area, ventromedial nucleus
RNA expression pattern · 19
TAOK1 → amygdala, anterior amygdaloid area, corpus callosum, external globus pallidus, globus pallidus, habenula, inferior colliculi, inferior ganglion of vagus nerve, internal globus pallidus, lateral geniculate nucleus, lateral septal nucleus, mammillary body, olfactory tubercle, pars compacta, pons, subthalamic nucleus, sural nerve, ventral tegmental area, ventromedial nucleus
Band · 2
TAOK1 → 11|11 B5, 17q11.2
Chr. · 2
TAOK1 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
TAOK1 → 29,551,903 bp, 77,498,641 bp
related to Clinical significance · 2
TAOK1 → DDIB, Mutations
2.7.11.1 · 1
TAOK1 → ↗
Aliases · 1
TAOK1 → TAOK1, KFC-B, MAP3K16, MARKK, PSK-2, PSK2, TAO1, hKFC-B, hTAO kinase 1, DDIB
BioGPS · 1
TAOK1 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene chr human band chromosome 17 kinase 11 location enzyme mouse serine tao1 external activity 551 903 end 29

TAOK1 relationships Subject–Predicate–Object triples

TTTA extracted 107 structured relationships around TAOK1. Examples in this analysis include TAOK1 → 2.7.11.1 → ↗ and TAOK1 → Aliases → TAOK1, KFC-B, MAP3K16, MARKK, PSK-2, PSK2, TAO1, hKFC-B, hTAO kinase 1, DDIB. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
TAOK12.7.11.11.00infobox
TAOK1AliasesTAOK1, KFC-B, MAP3K16, MARKK, PSK-2, PSK2, TAO1, hKFC-B, hTAO kinase 1, DDIB1.00infobox
TAOK1Band17q11.21.00infobox
TAOK1Band11|11 B51.00infobox
TAOK1Bgeecorpus callosum1.00infobox
TAOK1Bgeeglobus pallidus1.00infobox
TAOK1Bgeeinternal globus pallidus1.00infobox
TAOK1Bgeeventral tegmental area1.00infobox
TAOK1Bgeesubthalamic nucleus1.00infobox
TAOK1Bgeesural nerve1.00infobox
TAOK1Bgeepars compacta1.00infobox
TAOK1Bgeeinferior ganglion of vagus nerve1.00infobox
TAOK1Bgeepons1.00infobox
TAOK1Bgeeexternal globus pallidus1.00infobox
TAOK1Bgeeventromedial nucleus1.00infobox
TAOK1Bgeelateral septal nucleus1.00infobox
TAOK1Bgeeamygdala1.00infobox
TAOK1Bgeelateral geniculate nucleus1.00infobox
TAOK1Bgeeolfactory tubercle1.00infobox
TAOK1Bgeeanterior amygdaloid area1.00infobox
TAOK1Bgeemammillary body1.00infobox
TAOK1Bgeehabenula1.00infobox
TAOK1Bgeeinferior colliculi1.00infobox
TAOK1BioGPSMore reference expression data1.00infobox
TAOK1Chr.Chromosome 17 (human)1.00infobox
TAOK1Chr.Chromosome 11 (mouse)1.00infobox
TAOK1DatabasesNCBI: entry; OMA: entry1.00infobox
TAOK1End29,551,903 bp1.00infobox
TAOK1End77,498,641 bp1.00infobox
TAOK1EnsemblENSG000001605511.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around TAOK1 bring nearby vocabulary together. In this analysis, examples include Activity, Ddib and External. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Kinase
    • Location
    • Taok1
    • Chromosome
    • Human
    • Activity
    • Bp
    • Chr
    • Ddib
    • End
    • External
    • Mouse
  • enzyme
    • Tao1
    • Kinase
    • Taok1
    • Clinical
    • Encoded
    • Gene
    • Humans
    • Reading
    • References
    • Significance
    • Threonine-protein
    • Activity
  • TAOK1
    • Activity
    • Ddib
    • External
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Clinical
    • Reading
    • References
    • Significance
  • taok1
    • Activity
    • Ddib
    • External
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Clinical
    • Reading
    • References
    • Significance
  • clinical significance
    • Reading
    • References
    • Significance
    • Activity
    • Ddib
    • Enzyme
    • External
    • Tao1
    • Kinase
    • Location
    • Taok1
    • Chromosome

Connections between topic areas Semantic bridges

For TAOK1, one of the stronger structural bridges in this analysis connects TAOK1 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
TAOK1Overview · splits 3 ⟂ 3

Map overview Semantic statistics

TAOK1

Nodes6
Edges5
Triples107
Avg. degree1.67
Density0.333333
Components1

Source & methodology

TTTA analyzes the structure around TAOK1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — TAOK1 · EN edition · Analysis: TopicsToTalkAbout

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