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Mitogen-activated protein kinase kinase kinase 7 (MAP3K7), also known as TAK1, is an enzyme that in humans is encoded by the MAP3K7 gene.
The analysis highlights Interactions and Overview as prominent areas in the source structure around MAP3K7.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around MAP3K7 shows recurring relationship patterns in the source. For example, MAP3K7 → activation of NF-kappaB-inducing kinase activity, anoikis, apoptotic process, ATP binding, cytoplasm, cytosol, endosome membrane, Fc-epsilon receptor signaling pathway, histone H3 acetylation, I-kappaB kinase/NF-kappaB signaling, I-kappaB phosphorylation, identical protein binding, IkappaB kinase complex, interleukin-1-mediated signaling pathway, JNK cascade, kinase activity, magnesium ion binding, MAP kinase kinase kinase activity, membrane, metal ion binding Another extracted example is MAP3K7 → BMP, Following, Following TNF, Four, IL-1, In, LPS, MAP2K4/MKK4, MAP3K7P1/TAB1, MAP3K7P2/TAB2, MAPK8/JNK, NF-κB, NF-κB-independent, RIPK1, TAB1, TAB2/3, TAK1, TAK1has, TGF, TGFB. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
tak1 kinase protein bp human gene chr band shown also chromosome cell activation tnf structure humans mouse mitogen-activated location signaling
TTTA extracted 155 structured relationships around MAP3K7. Examples in this analysis include MAP3K7 → 2.7.11.25 → ↗ and MAP3K7 → Aliases → MAP3K7, MEKK7, TAK1, TGF1a, mitogen-activated protein kinase kinase kinase 7, FMD2, CSCF. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| MAP3K7 | 2.7.11.25 | ↗ | 1.00 | infobox |
| MAP3K7 | Aliases | MAP3K7, MEKK7, TAK1, TGF1a, mitogen-activated protein kinase kinase kinase 7, FMD2, CSCF | 1.00 | infobox |
| MAP3K7 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2EVA, 2YIY, 4GS6, 4L3P, 4L52, 4L53, 4O91, 5JGD, 5JGA | 1.00 | infobox |
| MAP3K7 | Band | 6q15 | 1.00 | infobox |
| MAP3K7 | Band | 4|4 A5 | 1.00 | infobox |
| MAP3K7 | Bgee | tendon of biceps brachii | 1.00 | infobox |
| MAP3K7 | Bgee | corpus epididymis | 1.00 | infobox |
| MAP3K7 | Bgee | internal globus pallidus | 1.00 | infobox |
| MAP3K7 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| MAP3K7 | Bgee | tail of epididymis | 1.00 | infobox |
| MAP3K7 | Bgee | caput epididymis | 1.00 | infobox |
| MAP3K7 | Bgee | ganglionic eminence | 1.00 | infobox |
| MAP3K7 | Bgee | corpus callosum | 1.00 | infobox |
| MAP3K7 | Bgee | Brodmann area 23 | 1.00 | infobox |
| MAP3K7 | Bgee | Achilles tendon | 1.00 | infobox |
| MAP3K7 | Bgee | genital tubercle | 1.00 | infobox |
| MAP3K7 | Bgee | tail of embryo | 1.00 | infobox |
| MAP3K7 | Bgee | Paneth cell | 1.00 | infobox |
| MAP3K7 | Bgee | molar | 1.00 | infobox |
| MAP3K7 | Bgee | aortic valve | 1.00 | infobox |
| MAP3K7 | Bgee | ventricular zone | 1.00 | infobox |
| MAP3K7 | Bgee | maxillary prominence | 1.00 | infobox |
| MAP3K7 | Bgee | somite | 1.00 | infobox |
| MAP3K7 | Bgee | vastus lateralis muscle | 1.00 | infobox |
| MAP3K7 | Bgee | mandibular prominence | 1.00 | infobox |
| MAP3K7 | BioGPS | More reference expression data | 1.00 | infobox |
| MAP3K7 | Chr. | Chromosome 6 (human) | 1.00 | infobox |
| MAP3K7 | Chr. | Chromosome 4 (mouse) | 1.00 | infobox |
| MAP3K7 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| MAP3K7 | End | 90,587,072 bp | 1.00 | infobox |
The concept neighborhoods around MAP3K7 bring nearby vocabulary together. In this analysis, examples include Enzyme, Gene and Search. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For MAP3K7, one of the stronger structural bridges in this analysis connects MAP3K7 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around MAP3K7 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — MAP3K7 · EN edition · Analysis: TopicsToTalkAbout