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Mitogen-activated protein kinase 12 is an enzyme that in humans is encoded by the MAP3K12 gene.
The analysis highlights Role in development, Interactions and Overview as prominent areas in the source structure around MAP3K12.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around MAP3K12 shows recurring relationship patterns in the source. For example, MAP3K12 → ATP binding, axon, cytoplasm, cytosol, growth cone, intracellular signal transduction, JNK cascade, JUN kinase kinase kinase activity, kinase activity, MAP kinase kinase kinase activity, MAPK cascade, membrane, negative regulation of motor neuron apoptotic process, nucleotide binding, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, phosphorylation, plasma membrane, positive regulation of ERK1 and ERK2 cascade, positive regulation of transcription, DNA-templated Another extracted example is MAP3K12 → anterior pituitary, aortic valve, ascending aorta, body of uterus, canal of the cervix, cerebellar vermis, external carotid artery, gastric mucosa, intercostal muscle, internal carotid artery, left ovary, lobe of cerebellum, otic placode, right frontal lobe, right hemisphere of cerebellum, right ovary, right uterine tube, submandibular gland, supraoptic nucleus, tunica media of zone of aorta. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
dlk neuronal kinase bp 12 gene chr human band protein jnk chromosome apoptosis axon role development location function migration phosphorylation
TTTA extracted 115 structured relationships around MAP3K12. Examples in this analysis include MAP3K12 → 2.7.11.25 → ↗ and MAP3K12 → Aliases → MAP3K12, DLK, MEKK12, MUK, ZPK, ZPKP1, mitogen-activated protein kinase kinase kinase 12, HP09298. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| MAP3K12 | 2.7.11.25 | ↗ | 1.00 | infobox |
| MAP3K12 | Aliases | MAP3K12, DLK, MEKK12, MUK, ZPK, ZPKP1, mitogen-activated protein kinase kinase kinase 12, HP09298 | 1.00 | infobox |
| MAP3K12 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5CEN, 5CEP, 5CEQ, 5CEO | 1.00 | infobox |
| MAP3K12 | Band | 12q13.13 | 1.00 | infobox |
| MAP3K12 | Band | 15|15 F3 | 1.00 | infobox |
| MAP3K12 | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| MAP3K12 | Bgee | gastric mucosa | 1.00 | infobox |
| MAP3K12 | Bgee | right uterine tube | 1.00 | infobox |
| MAP3K12 | Bgee | right ovary | 1.00 | infobox |
| MAP3K12 | Bgee | right frontal lobe | 1.00 | infobox |
| MAP3K12 | Bgee | anterior pituitary | 1.00 | infobox |
| MAP3K12 | Bgee | canal of the cervix | 1.00 | infobox |
| MAP3K12 | Bgee | cerebellar vermis | 1.00 | infobox |
| MAP3K12 | Bgee | body of uterus | 1.00 | infobox |
| MAP3K12 | Bgee | left ovary | 1.00 | infobox |
| MAP3K12 | Bgee | ascending aorta | 1.00 | infobox |
| MAP3K12 | Bgee | aortic valve | 1.00 | infobox |
| MAP3K12 | Bgee | supraoptic nucleus | 1.00 | infobox |
| MAP3K12 | Bgee | otic placode | 1.00 | infobox |
| MAP3K12 | Bgee | submandibular gland | 1.00 | infobox |
| MAP3K12 | Bgee | internal carotid artery | 1.00 | infobox |
| MAP3K12 | Bgee | lobe of cerebellum | 1.00 | infobox |
| MAP3K12 | Bgee | tunica media of zone of aorta | 1.00 | infobox |
| MAP3K12 | Bgee | external carotid artery | 1.00 | infobox |
| MAP3K12 | Bgee | intercostal muscle | 1.00 | infobox |
| MAP3K12 | BioGPS | More reference expression data | 1.00 | infobox |
| MAP3K12 | Chr. | Chromosome 12 (human) | 1.00 | infobox |
| MAP3K12 | Chr. | Chromosome 15 (mouse) | 1.00 | infobox |
| MAP3K12 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| MAP3K12 | End | 53,500,063 bp | 1.00 | infobox |
The concept neighborhoods around MAP3K12 bring nearby vocabulary together. In this analysis, examples include Gene, Protein and Activity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For MAP3K12, one of the stronger structural bridges in this analysis connects MAP3K12 with Role in development. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around MAP3K12 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Role in development, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — MAP3K12 · EN edition · Analysis: TopicsToTalkAbout