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MAP3K12

Mitogen-activated protein kinase 12 is an enzyme that in humans is encoded by the MAP3K12 gene.

Role in development, Interactions & Overview

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Role in development

6 related topics

Interactions

4 related topics

Overview

2 related topics

Key facts & relationships

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2.7.11.25
Aliases
MAP3K12, DLK, MEKK12, MUK, ZPK, ZPKP1, mitogen-activated protein kinase kinase kinase 12, HP09298
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5CEN, 5CEP, 5CEQ, 5CEO
Band
12q13.13 · 15|15 F3
Bgee
right hemisphere of cerebellum · gastric mucosa · right uterine tube · right ovary · right frontal lobe
BioGPS
More reference expression data

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Overview

Interactions

Role in development

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Map overview Semantic statistics

MAP3K12

Nodes16
Edges15
Triples115
Avg. degree1.88
Density0.125
Components1

How this topic connects Entity context

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MAP3K12

Top relations

Gene ontology · 29
MAP3K12 → ATP binding, axon, cytoplasm, cytosol, growth cone, intracellular signal transduction, JNK cascade, JUN kinase kinase kinase activity, kinase activity, MAP kinase kinase kinase activity, MAPK cascade, membrane, negative regulation of motor neuron apoptotic process, nucleotide binding, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, phosphorylation, plasma membrane, positive regulation of ERK1 and ERK2 cascade, positive regulation of transcription, DNA-templated
Bgee · 20
MAP3K12 → anterior pituitary, aortic valve, ascending aorta, body of uterus, canal of the cervix, cerebellar vermis, external carotid artery, gastric mucosa, intercostal muscle, internal carotid artery, left ovary, lobe of cerebellum, otic placode, right frontal lobe, right hemisphere of cerebellum, right ovary, right uterine tube, submandibular gland, supraoptic nucleus, tunica media of zone of aorta
RNA expression pattern · 20
MAP3K12 → anterior pituitary, aortic valve, ascending aorta, body of uterus, canal of the cervix, cerebellar vermis, external carotid artery, gastric mucosa, intercostal muscle, internal carotid artery, left ovary, lobe of cerebellum, otic placode, right frontal lobe, right hemisphere of cerebellum, right ovary, right uterine tube, submandibular gland, supraoptic nucleus, tunica media of zone of aorta
related to Role in development · 16
MAP3K12 → Another, C-Jun N-terminal, DLK, For, In, It, JIP, JIP3, JNK, MAP2K4/7, MAP2K7, NGF, Several, The, There, This
related to Interactions · 3
MAP3K12 → MAP2K7, MAPK8IP1, MAPK8IP2
Band · 2
MAP3K12 → 12q13.13, 15|15 F3
Chr. · 2
MAP3K12 → Chromosome 12 (human), Chromosome 15 (mouse)
End · 2
MAP3K12 → 102,425,499 bp, 53,500,063 bp
2.7.11.25 · 1
MAP3K12 → ↗
Aliases · 1
MAP3K12 → MAP3K12, DLK, MEKK12, MUK, ZPK, ZPKP1, mitogen-activated protein kinase kinase kinase 12, HP09298

Important terminology Word statistics

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Important terminology

dlk neuronal kinase bp 12 gene chr human band protein jnk chromosome apoptosis axon role development location function migration phosphorylation

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MAP3K122.7.11.251.00infobox
MAP3K12AliasesMAP3K12, DLK, MEKK12, MUK, ZPK, ZPKP1, mitogen-activated protein kinase kinase kinase 12, HP092981.00infobox
MAP3K12Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5CEN, 5CEP, 5CEQ, 5CEO1.00infobox
MAP3K12Band12q13.131.00infobox
MAP3K12Band15|15 F31.00infobox
MAP3K12Bgeeright hemisphere of cerebellum1.00infobox
MAP3K12Bgeegastric mucosa1.00infobox
MAP3K12Bgeeright uterine tube1.00infobox
MAP3K12Bgeeright ovary1.00infobox
MAP3K12Bgeeright frontal lobe1.00infobox
MAP3K12Bgeeanterior pituitary1.00infobox
MAP3K12Bgeecanal of the cervix1.00infobox
MAP3K12Bgeecerebellar vermis1.00infobox
MAP3K12Bgeebody of uterus1.00infobox
MAP3K12Bgeeleft ovary1.00infobox
MAP3K12Bgeeascending aorta1.00infobox
MAP3K12Bgeeaortic valve1.00infobox
MAP3K12Bgeesupraoptic nucleus1.00infobox
MAP3K12Bgeeotic placode1.00infobox
MAP3K12Bgeesubmandibular gland1.00infobox
MAP3K12Bgeeinternal carotid artery1.00infobox
MAP3K12Bgeelobe of cerebellum1.00infobox
MAP3K12Bgeetunica media of zone of aorta1.00infobox
MAP3K12Bgeeexternal carotid artery1.00infobox
MAP3K12Bgeeintercostal muscle1.00infobox
MAP3K12BioGPSMore reference expression data1.00infobox
MAP3K12Chr.Chromosome 12 (human)1.00infobox
MAP3K12Chr.Chromosome 15 (mouse)1.00infobox
MAP3K12DatabasesNCBI: entry; OMA: entry1.00infobox
MAP3K12End53,500,063 bp1.00infobox

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