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Enhancer of zeste homolog 2 (EZH2) is a histone-lysine N-methyltransferase enzyme (EC 2.1.1.43) encoded by EZH2 gene, that participates in histone methylation and, ultimately, transcriptional repression. EZH2 catalyzes the addition of methyl groups to histone H3 at lysine 27, by using the cofactor S-adenosyl-L-methionine. Methylation activity of EZH2…
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methylation activity gene prc2 histone lysine also genes development cancer function complex cell cofactor inhibitor differentiation heterochromatin methyl transcription involved
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| EZH2 | 2.1.1.356 | ↗ | 1.00 | infobox |
| EZH2 | Aliases | EZH2, ENX-1, ENX1, EZH1, EZH2b, KMT6, KMT6A, WVS, WVS2, enhancer of zeste 2 polycomb repressive complex 2 subunit | 1.00 | infobox |
| EZH2 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4MI0, 4MI5, 5HYN, 5IJ8, 5IJ7 | 1.00 | infobox |
| EZH2 | Band | 7q36.1 | 1.00 | infobox |
| EZH2 | Band | 6 B2.3|6 22.92 cM | 1.00 | infobox |
| EZH2 | Bgee | ganglionic eminence | 1.00 | infobox |
| EZH2 | Bgee | ventricular zone | 1.00 | infobox |
| EZH2 | Bgee | buccal mucosa cell | 1.00 | infobox |
| EZH2 | Bgee | left testis | 1.00 | infobox |
| EZH2 | Bgee | right testis | 1.00 | infobox |
| EZH2 | Bgee | sperm | 1.00 | infobox |
| EZH2 | Bgee | testicle | 1.00 | infobox |
| EZH2 | Bgee | gingival epithelium | 1.00 | infobox |
| EZH2 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| EZH2 | Bgee | skin of abdomen | 1.00 | infobox |
| EZH2 | Bgee | tail of embryo | 1.00 | infobox |
| EZH2 | Bgee | secondary oocyte | 1.00 | infobox |
| EZH2 | Bgee | genital tubercle | 1.00 | infobox |
| EZH2 | Bgee | zygote | 1.00 | infobox |
| EZH2 | Bgee | primary oocyte | 1.00 | infobox |
| EZH2 | Bgee | primitive streak | 1.00 | infobox |
| EZH2 | Bgee | medial ganglionic eminence | 1.00 | infobox |
| EZH2 | Bgee | thymus | 1.00 | infobox |
| EZH2 | BioGPS | More reference expression data | 1.00 | infobox |
| EZH2 | Chr. | Chromosome 7 (human) | 1.00 | infobox |
| EZH2 | Chr. | Chromosome 6 (mouse) | 1.00 | infobox |
| EZH2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| EZH2 | End | 148,884,321 bp | 1.00 | infobox |
| EZH2 | End | 47,595,341 bp | 1.00 | infobox |
| EZH2 | Ensembl | ENSG00000106462 | 1.00 | infobox |
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