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Methyltransferase

Methyltransferases are a large group of enzymes that all methylate their substrates but can be split into several subclasses based on their structural features. The most common class of methyltransferases is class I, all of which contain a Rossmann fold for binding S-Adenosyl methionine (SAM). Class II methyltransferases contain a SET domain, which are…

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Map overview Semantic statistics

Methyltransferase

Nodes105
Edges104
Triples104
Avg. degree1.98
Density0.019048
Components1

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Methyltransferase

Top relations

related to Further reading · 22
Methyltransferase → Cell Signaling Technology, Depression, DNA Methylation, DNA MethyltransferaseA, Flintbox, Gene Expression, Genetic, Histone Lysine Methylation, Histone Methyltransferases, Medicine Medical Subject Headings, MeSH, Methylation, Methylphosphate Capping Enzyme, Methyltransferases, National Library, Nature Scitable, News-Medical, Nutrition, Psychology Today, Structure
related to Natural product methyltransferases · 18
Methyltransferase → Archived, Catechol-O-methyltransferase, COMT, HNMT, Important, Like, Methyl, N-methyltransferase, Natural, NPMTs, O-methyltransferases, PNMT, Reflective, SAH, SAM, The, These, Wayback Machine
related to N-terminal methyltransferases · 16
Methyltransferase → Alanine, For, Known, N-alpha, N-terminal, Proline, RCC-1, Retinoblastoma, SAH, SAM, Serine, The, The N-terminal, This, When RCC-1, X-Proline-Lysine
related to Histone methyltransferases · 15
Methyltransferase → Arginine, DNA, Either, H3, H4, Histone, Increased, Lysine, Methyl, Most, RNAs, SAM, The, They, This
related to DNA/RNA methyltransferases · 13
Methyltransferase → DNA, DNMT1, DNMT2, DNMT3, In, Many, Methylation, O-methylation, RNA, S-adenosylmethionine, Specific RNA, These, TRDMT1
related to Clinical significance · 10
Methyltransferase → As, Cancer, DNA, DNMT, Fragile, ICF, Inhibition, Plasmid, Rett, RNA
has application · 4
Methyltransferase → Recent, S-Adenosyl, SAM, The
related to Examples · 3
Methyltransferase → Catechol-O-methyltransferaseDNA, Examples, Methyltetrahydrofolate-homocysteine

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Important terminology

methyltransferases dna methylation methyl protein sam histone class methionine enzymes rna types methylated proteins group substrates cancer enzyme pathways transfer

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ICFinstance ofanomalous DNA methylation is associated with genetic disorders0.80text
Rett syndromeinstance ofanomalous DNA methylation is associated with genetic disorders0.80text
and Fragile X syndromeinstance ofanomalous DNA methylation is associated with genetic disorders0.80text
Methyltransferasehas applicationRecent0.60section
Methyltransferasehas applicationS-Adenosyl0.60section
Methyltransferasehas applicationSAM0.60section
Methyltransferasehas applicationThe0.60section
Methyltransferaserelated to Clinical significanceAs0.60section
Methyltransferaserelated to Clinical significanceDNA0.60section
Methyltransferaserelated to Clinical significanceICF0.60section
Methyltransferaserelated to Clinical significanceRett0.60section
Methyltransferaserelated to Clinical significanceFragile0.60section

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