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AEBP2

Adipocyte Enhancer-Binding Protein is a zinc finger protein that in humans is encoded by the evolutionarily well-conserved gene AEBP2. It was initially identified due to its binding capability to the promoter of the adipocyte P2 gene, and was therefore named Adipocyte Enhancer Binding Protein 2. AEBP2 is a potential targeting protein for the mammalian…

Function, Clinical significance & Overview

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Function

RepressorNeural crest
2 related topics

Clinical significance

Waardenburg's syndromeHirschsprung's disease
2 related topics

Overview

Zinc fingerGenePromoterPolycomb Repression Complex 2
4 related topics

Key facts & relationships

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Aliases
AEBP2, AE binding protein 2
Band
12p12.3 · 6|6 G2
Bgee
Achilles tendon · retinal pigment epithelium · skin of arm · caput epididymis · pancreatic epithelial cell
BioGPS
n/a
Chr.
Chromosome 12 (human) · Chromosome 6 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Function

Clinical significance

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Map overview Semantic statistics

AEBP2

Nodes12
Edges11
Triples86
Avg. degree1.83
Density0.166667
Components1

How this topic connects Entity context

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AEBP2

Top relations

Bgee · 20
AEBP2 → Achilles tendon, buccal mucosa cell, caput epididymis, ciliary body, condyle, endothelial cell of lymphatic vessel, epithelium of nasopharynx, fossa, gingival epithelium, medullary collecting duct, otic placode, palpebral conjunctiva, pancreatic epithelial cell, Paneth cell, renal corpuscle, retinal pigment epithelium, saccule, skin of arm, tail of epididymis, vestibular membrane of cochlear duct
RNA expression pattern · 20
AEBP2 → Achilles tendon, buccal mucosa cell, caput epididymis, ciliary body, condyle, endothelial cell of lymphatic vessel, epithelium of nasopharynx, fossa, gingival epithelium, medullary collecting duct, otic placode, palpebral conjunctiva, pancreatic epithelial cell, Paneth cell, renal corpuscle, retinal pigment epithelium, saccule, skin of arm, tail of epididymis, vestibular membrane of cochlear duct
Gene ontology · 16
AEBP2 → chromatin organization, DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, ESC/E(Z) complex, metal ion binding, negative regulation of gene expression, epigenetic, negative regulation of transcription by RNA polymerase II, nucleic acid binding, nucleoplasm, nucleus, protein binding, regulation of transcription, DNA-templated, RNA polymerase II cis-regulatory region sequence-specific DNA binding, transcription corepressor activity, transcription, DNA-templated
related to Function · 4
AEBP2 → DNA-binding, It, PRC2, PRC2-mediated
related to Clinical significance · 3
AEBP2 → Diseases, Hirschsprung's, Waardenburg's
Band · 2
AEBP2 → 12p12.3, 6|6 G2
Chr. · 2
AEBP2 → Chromosome 12 (human), Chromosome 6 (mouse)
End · 2
AEBP2 → 140,624,198 bp, 19,720,801 bp
related to External links · 2
AEBP2 → Human AEBP2, UCSC Genome Browser
Aliases · 1
AEBP2 → AEBP2, AE binding protein 2

Important terminology Word statistics

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Important terminology

gene protein bp human chr band chromosome 12 complex location binding prc2 adipocyte mouse function external targeting mammalian 720 801

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
AEBP2AliasesAEBP2, AE binding protein 21.00infobox
AEBP2Band12p12.31.00infobox
AEBP2Band6|6 G21.00infobox
AEBP2BgeeAchilles tendon1.00infobox
AEBP2Bgeeretinal pigment epithelium1.00infobox
AEBP2Bgeeskin of arm1.00infobox
AEBP2Bgeecaput epididymis1.00infobox
AEBP2Bgeepancreatic epithelial cell1.00infobox
AEBP2Bgeebuccal mucosa cell1.00infobox
AEBP2Bgeepalpebral conjunctiva1.00infobox
AEBP2Bgeeepithelium of nasopharynx1.00infobox
AEBP2Bgeetail of epididymis1.00infobox
AEBP2Bgeegingival epithelium1.00infobox
AEBP2Bgeecondyle1.00infobox
AEBP2Bgeefossa1.00infobox
AEBP2BgeePaneth cell1.00infobox
AEBP2Bgeemedullary collecting duct1.00infobox
AEBP2Bgeerenal corpuscle1.00infobox
AEBP2Bgeesaccule1.00infobox
AEBP2Bgeevestibular membrane of cochlear duct1.00infobox
AEBP2Bgeeciliary body1.00infobox
AEBP2Bgeeendothelial cell of lymphatic vessel1.00infobox
AEBP2Bgeeotic placode1.00infobox
AEBP2BioGPSn/a1.00infobox
AEBP2Chr.Chromosome 12 (human)1.00infobox
AEBP2Chr.Chromosome 6 (mouse)1.00infobox
AEBP2DatabasesNCBI: entry; OMA: entry1.00infobox
AEBP2End19,720,801 bp1.00infobox
AEBP2End140,624,198 bp1.00infobox
AEBP2EnsemblENSG000001391541.00infobox

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