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PRC1: Function, Interactions & Structure

Protein Regulator of cytokinesis 1 (PRC1) is a protein that in humans is encoded by the PRC1 gene and is involved in cytokinesis.

Language: English [EN]
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PRC1 topic overview

The analysis highlights Function, Interactions and Structure as prominent areas in the source structure around PRC1.

Related topics
17
Source areas
4
Connected nodes
21
Extracted relationships
113
Related term clusters
12
Bridge connections
21

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 6 topics
Interactions · 6 topics
Overview · 3 topics
Structure · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
PRC1, ASE1, protein regulator of cytokinesis 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3NRX, 3NRY, 4L3I, 4L6Y
Band
15q26.1 · 7 D2|7 45.62 cM
Bgee
ventricular zone · ganglionic eminence · gonad · testicle · left testis
BioGPS
More reference expression data
Chr.
Chromosome 15 (human) · Chromosome 7 (mouse)

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Structure

Interactions

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How PRC1 connects Entity context

The extracted context around PRC1 shows recurring relationship patterns in the source. For example, PRC1 → cell cycle, cell division, contractile ring, cytokinesis, cytoplasm, cytoskeleton, cytosol, identical protein binding, kinesin binding, microtubule, microtubule binding, microtubule bundle formation, microtubule cytoskeleton organization, midbody, mitotic spindle elongation, nucleus, positive regulation of cell population proliferation, protein binding, protein kinase binding, regulation of cytokinesis Another extracted example is PRC1 → bone marrow, bone marrow cell, endothelial cell of lymphatic vessel, ganglionic eminence, genital tubercle, gonad, left testis, morula, mucosa of transverse colon, primary oocyte, right testis, secondary oocyte, spermatocyte, stromal cell of endometrium, tail of embryo, testicle, ventricular zone, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

PRC1

Top relations

Gene ontology · 23
PRC1 → cell cycle, cell division, contractile ring, cytokinesis, cytoplasm, cytoskeleton, cytosol, identical protein binding, kinesin binding, microtubule, microtubule binding, microtubule bundle formation, microtubule cytoskeleton organization, midbody, mitotic spindle elongation, nucleus, positive regulation of cell population proliferation, protein binding, protein kinase binding, regulation of cytokinesis
Bgee · 18
PRC1 → bone marrow, bone marrow cell, endothelial cell of lymphatic vessel, ganglionic eminence, genital tubercle, gonad, left testis, morula, mucosa of transverse colon, primary oocyte, right testis, secondary oocyte, spermatocyte, stromal cell of endometrium, tail of embryo, testicle, ventricular zone, zygote
RNA expression pattern · 18
PRC1 → bone marrow, bone marrow cell, endothelial cell of lymphatic vessel, ganglionic eminence, genital tubercle, gonad, left testis, morula, mucosa of transverse colon, primary oocyte, right testis, secondary oocyte, spermatocyte, stromal cell of endometrium, tail of embryo, testicle, ventricular zone, zygote
related to Function · 10
PRC1 → Additionally, Ase1, CDKs, Correspondingly, Feo, G1, G2/M, MAP65, MAPs, SPD-1
related to Interactions · 10
PRC1 → C-terminal, C-terminus, CDK1, CDKs, CYK-4, Kinesin-4, MAP, PLK1, Thr-602, TRIM37
related to Role in cytokinesis · 5
PRC1 → CDK1, Kinesin-4, PRC1’s, This PRC1-Kinesin-4, Upon
related to Structure · 5
PRC1 → C-terminal, Consisting, Kinesin-4, N-terminal, PRC1’s
Band · 2
PRC1 → 15q26.1, 7 D2|7 45.62 cM
Chr. · 2
PRC1 → Chromosome 15 (human), Chromosome 7 (mouse)
End · 2
PRC1 → 80,316,259 bp, 90,995,629 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cytokinesis spindle protein bp chr human band microtubule gene midzone chromosome 15 phosphorylation cdk1 kinesin-4 microtubules cell regulator location proteins

PRC1 relationships Subject–Predicate–Object triples

TTTA extracted 113 structured relationships around PRC1. Examples in this analysis include PRC1 → Aliases → PRC1, ASE1, protein regulator of cytokinesis 1 and PRC1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3NRX, 3NRY, 4L3I, 4L6Y. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PRC1AliasesPRC1, ASE1, protein regulator of cytokinesis 11.00infobox
PRC1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3NRX, 3NRY, 4L3I, 4L6Y1.00infobox
PRC1Band15q26.11.00infobox
PRC1Band7 D2|7 45.62 cM1.00infobox
PRC1Bgeeventricular zone1.00infobox
PRC1Bgeeganglionic eminence1.00infobox
PRC1Bgeegonad1.00infobox
PRC1Bgeetesticle1.00infobox
PRC1Bgeeleft testis1.00infobox
PRC1Bgeeright testis1.00infobox
PRC1Bgeebone marrow1.00infobox
PRC1Bgeestromal cell of endometrium1.00infobox
PRC1Bgeemucosa of transverse colon1.00infobox
PRC1Bgeebone marrow cell1.00infobox
PRC1Bgeeprimary oocyte1.00infobox
PRC1Bgeesecondary oocyte1.00infobox
PRC1Bgeespermatocyte1.00infobox
PRC1Bgeezygote1.00infobox
PRC1Bgeetail of embryo1.00infobox
PRC1Bgeegenital tubercle1.00infobox
PRC1Bgeemorula1.00infobox
PRC1Bgeeendothelial cell of lymphatic vessel1.00infobox
PRC1BioGPSMore reference expression data1.00infobox
PRC1Chr.Chromosome 15 (human)1.00infobox
PRC1Chr.Chromosome 7 (mouse)1.00infobox
PRC1DatabasesNCBI: entry; OMA: entry1.00infobox
PRC1End90,995,629 bp1.00infobox
PRC1End80,316,259 bp1.00infobox
PRC1EnsemblENSG000001989011.00infobox
PRC1Entrez90551.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around PRC1 bring nearby vocabulary together. In this analysis, examples include Spindle, Protein and Cdk1. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • PRC1
    • Spindle
    • Protein
    • Cdk1
    • Phosphorylation
    • Microtubule
    • Anaphase
    • Shown
    • Structure
    • Domain
    • Gene
    • Proteins
    • Kinesin-4
  • prc1
    • Spindle
    • Protein
    • Cdk1
    • Phosphorylation
    • Microtubule
    • Anaphase
    • Shown
    • Structure
    • Domain
    • Gene
    • Proteins
    • Kinesin-4
  • protein
    • Cytokinesis
    • Regulator
    • Gene
    • Function
    • O43663
    • Pdb
    • Uniprot
    • End
    • Location
    • Chromosome
    • Human
    • Prc1
  • cytokinesis
    • Protein
    • Regulator
    • Gene
    • Spindle
    • Prc1
    • Function
    • Mitotic
    • Nucleus
    • O43663
    • Pdb
    • Uniprot
    • Cell
  • gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Function
    • Mouse
    • Protein
    • End
    • Regulator
    • Band
    • External
  • function
    • Location
    • Chromosome
    • External
    • Gene
    • Human
    • Bp
    • Chr
    • Mitotic
    • Mouse
    • Nucleus
    • O43663
    • Pdb
  • structure
    • External
    • Function
    • Pdb
    • Location
    • Regulator
    • Role
    • Chromosome
    • Gene
    • Human
    • Proteins
    • Bp
    • Chr
  • spectrin
    • C-terminal
    • Domain
    • Rod
    • Shown
    • Microtubules
    • Protein
    • Prc1

Connections between topic areas Semantic bridges

For PRC1, one of the stronger structural bridges in this analysis connects PRC1 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PRC1 — Function · splits 15 ⟂ 7
PRC1 — Interactions · splits 15 ⟂ 7
PRC1 — Overview · splits 18 ⟂ 4
PRC1 — Structure · splits 19 ⟂ 3

Map overview Semantic statistics

PRC1

Nodes22
Edges21
Triples113
Avg. degree1.91
Density0.090909
Components1

Source & methodology

TTTA analyzes the structure around PRC1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PRC1 · EN edition · Analysis: TopicsToTalkAbout

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