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The SET domain is a protein domain that typically has methyltransferase activity. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su(var)3-9 and 'Enhancer of zeste' proteins, from which the acronym SET is derived [Su(var)3-9, Enhancer-of-zeste…
The analysis highlights Art and Regions as prominent areas in the source structure around SET domain.
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Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
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The extracted context around SET domain shows recurring relationship patterns in the source. For example, SET domain → ASH1L, AWS, BAT8, EHMT1, EHMT2, EZH1, EZH2MLL, FP13812, Human, KMT5B, MLL2, MLL3, MLL5NSD1, NSD2, NSD3PRDM1, PRDM2, PRDM5SETD1A, SET, SETD2, SETD3 Another extracted example is SET domain → DIM-5, H3, HKMTs, Neurospora, Rubisco, Rubisco LSMT, SET7, SET9, SETD7, Su, The SET. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
set domain protein structure histone substrate lysine proteins three residues methyltransferase conserved region function interpro part human enzyme adomet cofactor
TTTA extracted 77 structured relationships around SET domain. Examples in this analysis include SET domain → AlphaFold → IPR001214 and SET domain → AlphaFold → PF00856. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| SET domain | AlphaFold | IPR001214 | 1.00 | infobox |
| SET domain | AlphaFold | PF00856 | 1.00 | infobox |
| SET domain | Available protein structures: | IPR001214 | 1.00 | infobox |
| SET domain | Available protein structures: | PF00856 | 1.00 | infobox |
| SET domain | InterPro | IPR001214 | 1.00 | infobox |
| SET domain | PDB | IPR001214 PF00856 (ECOD; PDBsum) | 1.00 | infobox |
| SET domain | Pfam | PF00856 | 1.00 | infobox |
| SET domain | SCOP2 | 1ml9 / SCOPe / SUPFAM | 1.00 | infobox |
| SET domain | SMART | SM0468 | 1.00 | infobox |
| SET domain | Symbol | SET | 1.00 | infobox |
| SET domain | is a | protein domain that typically has methyltransferase activity | 0.90 | text |
| SET domain | related to Associated domains | The N-terminal | 0.60 | section |
The concept neighborhoods around SET domain bring nearby vocabulary together. In this analysis, examples include Set, Structure and Methyltransferase. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For SET domain, one of the stronger structural bridges in this analysis connects SET domain with Examples. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around SET domain to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art & Regions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — SET domain · EN edition · Analysis: TopicsToTalkAbout