Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

SMARCA4

Transcription activator BRG1 also known as ATP-dependent chromatin remodeler SMARCA4 is a protein that in humans is encoded by the SMARCA4 gene.

Products, Interactions & Function

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around SMARCA4. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Interactions

24 related topics

Function

14 related topics

Clinical significance

3 related topics

Overview

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SMARCA4, BAF190, BAF190A, BRG1, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2, hSNF2b, CSS4, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a,…
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2GRC, 2H60, 3UVD, 5DKD, 5EA1
Band
19p13.2 · 9 A3|9 7.84 cM
Bgee
ganglionic eminence · tendon of biceps brachii · ventricular zone · amniotic fluid · epithelium of nasopharynx
BioGPS
More reference expression data
Chr.
Chromosome 19 (human) · Chromosome 9 (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

SMARCA4

Nodes48
Edges47
Triples151
Avg. degree1.96
Density0.041667
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

SMARCA4

Top relations

Gene ontology · 56
SMARCA4 → androgen receptor binding, ATP binding, ATP-dependent activity, acting on DNA, ATPase activity, beta-catenin-TCF complex assembly, chromatin organization, chromatin remodeling, DNA binding, DNA polymerase binding, extracellular space, helicase activity, histone binding, hydrolase activity, hydrolase activity, acting on acid anhydrides, interleukin-7-mediated signaling pathway, lysine-acetylated histone binding, membrane, nBAF complex, negative regulation of androgen receptor signaling pathway, negative regulation of cell growth
related to Interactions · 23
SMARCA4 → ACTL6A, ARID1A, ARID1B, BRCA1, CBX5, CCNE1, CREBBP, CTNNB1, ESR1, FANCA, HSP90B1, ING1, Myc, NR3C1, P53, PHB, POLR2A, SIN3A, SMARCB1, SMARCC1
Bgee · 19
SMARCA4 → amniotic fluid, endothelial cell, epithelium of nasopharynx, ganglionic eminence, Gonadal ridge, hand, internal carotid artery, mandibular prominence, maxillary prominence, middle temporal gyrus, otic vesicle, primary visual cortex, right hemisphere of cerebellum, Rostral migratory stream, somite, sural nerve, tail of embryo, tendon of biceps brachii, ventricular zone
RNA expression pattern · 19
SMARCA4 → amniotic fluid, endothelial cell, epithelium of nasopharynx, ganglionic eminence, Gonadal ridge, hand, internal carotid artery, mandibular prominence, maxillary prominence, middle temporal gyrus, otic vesicle, primary visual cortex, right hemisphere of cerebellum, Rostral migratory stream, somite, sural nerve, tail of embryo, tendon of biceps brachii, ventricular zone
related to Clinical significance · 8
SMARCA4 → ATP, ATPase, BRG1, DNA-binding, In, Later, Mutations, These
Band · 2
SMARCA4 → 19p13.2, 9 A3|9 7.84 cM
Chr. · 2
SMARCA4 → Chromosome 19 (human), Chromosome 9 (mouse)
End · 2
SMARCA4 → 11,065,395 bp, 21,615,526 bp
Aliases · 1
SMARCA4 → SMARCA4, BAF190, BAF190A, BRG1, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2, hSNF2b, CSS4, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a,…
Available structures · 1
SMARCA4 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2GRC, 2H60, 3UVD, 5DKD, 5EA1

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

brg1 chromatin gene bp human chr band protein atpase development cancer mutations chromosome 19 transcription swi snf expression cell atp-dependent

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SMARCA4AliasesSMARCA4, BAF190, BAF190A, BRG1, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2, hSNF2b, CSS4, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a,…1.00infobox
SMARCA4Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2GRC, 2H60, 3UVD, 5DKD, 5EA11.00infobox
SMARCA4Band19p13.21.00infobox
SMARCA4Band9 A3|9 7.84 cM1.00infobox
SMARCA4Bgeeganglionic eminence1.00infobox
SMARCA4Bgeetendon of biceps brachii1.00infobox
SMARCA4Bgeeventricular zone1.00infobox
SMARCA4Bgeeamniotic fluid1.00infobox
SMARCA4Bgeeepithelium of nasopharynx1.00infobox
SMARCA4Bgeesural nerve1.00infobox
SMARCA4Bgeemiddle temporal gyrus1.00infobox
SMARCA4Bgeeprimary visual cortex1.00infobox
SMARCA4Bgeeendothelial cell1.00infobox
SMARCA4Bgeeright hemisphere of cerebellum1.00infobox
SMARCA4BgeeRostral migratory stream1.00infobox
SMARCA4Bgeeotic vesicle1.00infobox
SMARCA4Bgeehand1.00infobox
SMARCA4Bgeemandibular prominence1.00infobox
SMARCA4Bgeesomite1.00infobox
SMARCA4Bgeetail of embryo1.00infobox
SMARCA4Bgeeinternal carotid artery1.00infobox
SMARCA4BgeeGonadal ridge1.00infobox
SMARCA4Bgeemaxillary prominence1.00infobox
SMARCA4BioGPSMore reference expression data1.00infobox
SMARCA4Chr.Chromosome 19 (human)1.00infobox
SMARCA4Chr.Chromosome 9 (mouse)1.00infobox
SMARCA4DatabasesNCBI: entry; OMA: entry1.00infobox
SMARCA4End11,065,395 bp1.00infobox
SMARCA4End21,615,526 bp1.00infobox
SMARCA4EnsemblENSG000001276161.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.