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Co-stimulation

Co-stimulation is a secondary signal which immune cells rely on to activate an immune response in the presence of an antigen-presenting cell. In the case of T cells, two stimuli are required to fully activate their immune response. During the activation of lymphocytes, co-stimulation is often crucial to the development of an effective immune response.…

Applications, T cell co-stimulation & B cell co-stimulation

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Overview

T cell co-stimulation

B cell co-stimulation

Applications

Advanced semantic analysis

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Map overview Semantic statistics

Co-stimulation

Nodes66
Edges65
Triples40
Avg. degree1.97
Density0.030303
Components1

How this topic connects Entity context

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Co-stimulation

Top relations

related to B cell co-stimulation · 22
Co-stimulation → After C3b, BCR, C3b, C3d, C3dg, CD154, CD19, CD21, CD40, CD40L, CD81, CR2, It, MHC II, MHC-antigen, Microbes, TCR, Tfh, Th2, The
related to T cell co-stimulation · 9
Co-stimulation → Activation, APC, CTLA4, MHC, Mostly, PD1, TCR, The, This
has application · 8
Co-stimulation → Abatacept, Belatacept, London, Northwick Park Hospital, Orencia, T-cell, TGN1412, The
is a · 1
Co-stimulation → secondary signal which immune cells rely on to activate an immune response in the presence of an antigen-presenting cell

Important terminology Word statistics

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Important terminology

cell cells molecules co-stimulatory cd28 antigen also signal signaling activation icos expressed 41-bb cd27 receptor tcr immune different ox40 activate

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Co-stimulationis asecondary signal which immune cells rely on to activate an immune response in the presence of an antigen-presenting cell0.90text
Co-stimulationhas applicationAbatacept0.60section
Co-stimulationhas applicationOrencia0.60section
Co-stimulationhas applicationThe0.60section
Co-stimulationhas applicationT-cell0.60section
Co-stimulationhas applicationBelatacept0.60section
Co-stimulationhas applicationTGN14120.60section
Co-stimulationhas applicationNorthwick Park Hospital0.60section
Co-stimulationhas applicationLondon0.60section
Co-stimulationrelated to B cell co-stimulationBCR0.60section
Co-stimulationrelated to B cell co-stimulationMHC II0.60section
Co-stimulationrelated to B cell co-stimulationThe0.60section

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