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Cluster of differentiation 40, CD40 is a type I transmembrane protein found on antigen-presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.
Specific effects on cells, Interactions & Function
Explore the main themes, entities and connections around CD40. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| CD40 | Aliases | CD40, Bp50, CDW40, TNFRSF5, p50, CD40 (protein), CD40 molecule | 1.00 | infobox |
| CD40 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CZZ, 1D00, 1FLL, 1LB6, 3QD6, 5DMJ, 5IHL, 5DMI | 1.00 | infobox |
| CD40 | Band | 20q13.12 | 1.00 | infobox |
| CD40 | Band | 2 H3|2 85.38 cM | 1.00 | infobox |
| CD40 | Bgee | lymph node | 1.00 | infobox |
| CD40 | Bgee | right lung | 1.00 | infobox |
| CD40 | Bgee | spleen | 1.00 | infobox |
| CD40 | Bgee | upper lobe of left lung | 1.00 | infobox |
| CD40 | Bgee | left ovary | 1.00 | infobox |
| CD40 | Bgee | Descending thoracic aorta | 1.00 | infobox |
| CD40 | Bgee | right ovary | 1.00 | infobox |
| CD40 | Bgee | appendix | 1.00 | infobox |
| CD40 | Bgee | gastric mucosa | 1.00 | infobox |
| CD40 | Bgee | ascending aorta | 1.00 | infobox |
| CD40 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| CD40 | Bgee | tail of embryo | 1.00 | infobox |
| CD40 | Bgee | blood | 1.00 | infobox |
| CD40 | Bgee | external carotid artery | 1.00 | infobox |
| CD40 | Bgee | internal carotid artery | 1.00 | infobox |
| CD40 | Bgee | semi-lunar valve | 1.00 | infobox |
| CD40 | Bgee | thymus | 1.00 | infobox |
| CD40 | Bgee | vas deferens | 1.00 | infobox |
| CD40 | BioGPS | More reference expression data | 1.00 | infobox |
| CD40 | Chr. | Chromosome 20 (human) | 1.00 | infobox |
| CD40 | Chr. | Chromosome 2 (mouse) | 1.00 | infobox |
| CD40 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| CD40 | End | 46,129,863 bp | 1.00 | infobox |
| CD40 | End | 164,914,868 bp | 1.00 | infobox |
| CD40 | Ensembl | ENSG00000101017 | 1.00 | infobox |
| CD40 | Entrez | 958 | 1.00 | infobox |
These clusters group vocabulary that occurs around closely connected concepts in the source material.
Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.