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Complement receptor 2: Immunohistochemistry, Interactions & Isoforms

Complement receptor type 2 (CR2), also known as complement C3d receptor, Epstein–Barr virus receptor, and CD21 (cluster of differentiation 21), is a protein that in humans is encoded by the CR2 gene.

Language: English [EN]
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Complement receptor 2 topic overview

The analysis highlights Immunohistochemistry, Interactions and Isoforms as prominent areas in the source structure around Complement receptor 2.

Related topics
28
Source areas
4
Connected nodes
32
Extracted relationships
97
Concept neighborhoods
17
Bridge connections
32

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Immunohistochemistry · 11 topics
Interactions · 8 topics
Overview · 6 topics
Isoforms · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CR2, C3DR, CD21, CR, CVID7, SLEB9, complement component 3d receptor 2, complement C3d receptor 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GHQ, 1LY2, 1W2R, 1W2S, 2GSX, 3OED
Band
1q32.2 · 1 H6|1 98.44 cM
Bgee
secondary oocyte · spleen · appendix · lymph node · mucosa of ileum
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 1 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Isoforms

Immunohistochemistry

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Complement receptor 2 connects Entity context

The extracted context around Complement receptor 2 shows recurring relationship patterns in the source. For example, Complement receptor 2 → B cell differentiation, B cell proliferation, complement activation, classical pathway, complement binding, complement receptor activity, complement receptor mediated signaling pathway, DNA binding, extracellular exosome, immune response, immune system process, innate immune response, integral component of membrane, membrane, plasma membrane, protein binding, protein homodimerization activity, receptor complex, regulation of complement activation, signal transduction, transmembrane signaling receptor activity Another extracted example is Complement receptor 2 → appendix, blood, embryo, epithelium of nasopharynx, lymph node, mesenteric lymph nodes, mucosa of ileum, neural layer of retina, rectum, secondary oocyte, spermatid, spleen, subcutaneous adipose tissue, superficial temporal artery, testicle, tonsil, tunica adventitia of aorta, tunica media of zone of aorta. Use these groups to spot repeated connection types before inspecting the individual relationships.

Complement receptor 2

Top relations

Gene ontology · 23
Complement receptor 2 → B cell differentiation, B cell proliferation, complement activation, classical pathway, complement binding, complement receptor activity, complement receptor mediated signaling pathway, DNA binding, extracellular exosome, immune response, immune system process, innate immune response, integral component of membrane, membrane, plasma membrane, protein binding, protein homodimerization activity, receptor complex, regulation of complement activation, signal transduction, transmembrane signaling receptor activity
Bgee · 18
Complement receptor 2 → appendix, blood, embryo, epithelium of nasopharynx, lymph node, mesenteric lymph nodes, mucosa of ileum, neural layer of retina, rectum, secondary oocyte, spermatid, spleen, subcutaneous adipose tissue, superficial temporal artery, testicle, tonsil, tunica adventitia of aorta, tunica media of zone of aorta
RNA expression pattern · 18
Complement receptor 2 → appendix, blood, embryo, epithelium of nasopharynx, lymph node, mesenteric lymph nodes, mucosa of ileum, neural layer of retina, rectum, secondary oocyte, spermatid, spleen, subcutaneous adipose tissue, superficial temporal artery, testicle, tonsil, tunica adventitia of aorta, tunica media of zone of aorta
related to Interactions · 15
Complement receptor 2 → B-cell, Barr, C3, C3d, C3dg, CD19, CD81, Complement, CR2, EBV, Epstein, TAPA-1, The CR2-CD19-CD81, This, Yefenof
Band · 2
Complement receptor 2 → 1 H6|1 98.44 cM, 1q32.2
Chr. · 2
Complement receptor 2 → Chromosome 1 (human), Chromosome 1 (mouse)
End · 2
Complement receptor 2 → 194,859,024 bp, 207,489,895 bp
Aliases · 1
Complement receptor 2 → CR2, C3DR, CD21, CR, CVID7, SLEB9, complement component 3d receptor 2, complement C3d receptor 2
Available structures · 1
Complement receptor 2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GHQ, 1LY2, 1W2R, 1W2S, 2GSX, 3OED
BioGPS · 1
Complement receptor 2 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cr2 complement gene human receptor bp cr1 cells chr band cd21 c3d chromosome protein activation system tissue complex cell virus

Complement receptor 2 relationships Subject–Predicate–Object triples

TTTA extracted 97 structured relationships around Complement receptor 2. Examples in this analysis include Complement receptor 2 → Aliases → CR2, C3DR, CD21, CR, CVID7, SLEB9, complement component 3d receptor 2, complement C3d receptor 2 and Complement receptor 2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GHQ, 1LY2, 1W2R, 1W2S, 2GSX, 3OED. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Complement receptor 2AliasesCR2, C3DR, CD21, CR, CVID7, SLEB9, complement component 3d receptor 2, complement C3d receptor 21.00infobox
Complement receptor 2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GHQ, 1LY2, 1W2R, 1W2S, 2GSX, 3OED1.00infobox
Complement receptor 2Band1q32.21.00infobox
Complement receptor 2Band1 H6|1 98.44 cM1.00infobox
Complement receptor 2Bgeesecondary oocyte1.00infobox
Complement receptor 2Bgeespleen1.00infobox
Complement receptor 2Bgeeappendix1.00infobox
Complement receptor 2Bgeelymph node1.00infobox
Complement receptor 2Bgeemucosa of ileum1.00infobox
Complement receptor 2Bgeeepithelium of nasopharynx1.00infobox
Complement receptor 2Bgeetonsil1.00infobox
Complement receptor 2Bgeesuperficial temporal artery1.00infobox
Complement receptor 2Bgeetesticle1.00infobox
Complement receptor 2Bgeerectum1.00infobox
Complement receptor 2Bgeemesenteric lymph nodes1.00infobox
Complement receptor 2Bgeeblood1.00infobox
Complement receptor 2Bgeesubcutaneous adipose tissue1.00infobox
Complement receptor 2Bgeeneural layer of retina1.00infobox
Complement receptor 2Bgeespermatid1.00infobox
Complement receptor 2Bgeetunica media of zone of aorta1.00infobox
Complement receptor 2Bgeeembryo1.00infobox
Complement receptor 2Bgeetunica adventitia of aorta1.00infobox
Complement receptor 2BioGPSMore reference expression data1.00infobox
Complement receptor 2Chr.Chromosome 1 (human)1.00infobox
Complement receptor 2Chr.Chromosome 1 (mouse)1.00infobox
Complement receptor 2DatabasesNCBI: entry; OMA: entry1.00infobox
Complement receptor 2End207,489,895 bp1.00infobox
Complement receptor 2End194,859,024 bp1.00infobox
Complement receptor 2EnsemblENSG000001173221.00infobox
Complement receptor 2Entrez13801.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Complement receptor 2 bring nearby vocabulary together. In this analysis, examples include Receptor, Gene and System. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Complement receptor 2
    • Receptor
    • Gene
    • System
    • Cr2
    • Cd21
    • Cell
    • Differentiation
    • Encoded
    • Location
    • Virus
    • Activation
    • C3d
  • complement receptor 2
    • Gene
    • Receptor
    • System
    • Cr2
    • Differentiation
    • Cd21
    • Complex
    • Encoded
    • Location
    • Virus
    • Cell
    • Chromosome
  • protein
    • Mature
    • Virus
    • Receptor
    • Cells
    • Gene
    • Cr1
    • Mouse
    • Acids
    • Amino
    • Ca
    • Cd19
    • Complex
  • gene
    • Receptor
    • Location
    • Chromosome
    • Bp
    • Chr
    • Human
    • Mouse
    • Cr1
    • Virus
    • Band
    • Protein
    • External
  • complement system
    • Receptor
    • Gene
    • System
    • Cr2
    • Cd21
    • Differentiation
    • Encoded
    • Location
    • Virus
    • Activation
    • C3d
    • Chromosome
  • b cells
    • Mature
    • Activation
    • Cd19
    • Complex
    • Cr2
    • Follicular
    • System
    • Virus
    • Protein
    • Human
    • Complement
    • Cr1
  • b-cell receptor
    • Gene
    • Cell
    • Differentiation
    • Complex
    • Encoded
    • Location
    • Virus
    • Chromosome
    • Ic3b
    • Protein
    • Bp
    • Chr
  • epstein–barr virus
    • Differentiation
    • Protein
    • Receptor
    • Cells
    • Gene
    • Mouse
    • Complement
    • Cd19
    • Complex
    • Encoded
    • Location
    • Mature

Connections between topic areas Semantic bridges

For Complement receptor 2, one of the stronger structural bridges in this analysis connects Complement receptor 2 with Immunohistochemistry. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Complement receptor 2Immunohistochemistry · splits 21 ⟂ 12
Complement receptor 2Interactions · splits 24 ⟂ 9
Complement receptor 2Overview · splits 26 ⟂ 7
Complement receptor 2Isoforms · splits 29 ⟂ 4

Map overview Semantic statistics

Complement receptor 2

Nodes33
Edges32
Triples97
Avg. degree1.94
Density0.060606
Components1

Source & methodology

TTTA analyzes the structure around Complement receptor 2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Immunohistochemistry, Interactions & Isoforms, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Complement receptor 2 · EN edition · Analysis: TopicsToTalkAbout

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