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Research this topic
Explore the main themes, entities and connections around TNFRSF9. Start with the topic map, then use the sections below for research and deeper semantic analysis.
Explore this topic
Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.
Expression
18 related topics
Atherosclerosis
AtherosclerosisCardiovascular Disease (CVD)Adhesion moleculesIntracellular adhesion molecule-1Macrophages
6 related topics
Regulation of the immune system
2 related topics
Interactions
2 related topics
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
- Aliases
- TNFRSF9, 4-1BB, CD137, CDw137, ILA, tumor necrosis factor receptor superfamily member 9, TNF receptor superfamily member 9
- Available structures
- Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1D0J
- Band
- 1p36.23 · 4 E2|4 81.52 cM
- Bgee
- buccal mucosa cell · lymph node · cartilage tissue · testicle · blood
- BioGPS
- More reference expression data
- Chr.
- Chromosome 1 (human) · Chromosome 4 (mouse)
Topics to explore
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.Browse the full topic structure. Each item opens a new analysis centered on that subject.
Overview
Expression
- T cells T cell
- Antigen Presenting Cells (APCs) Antigen-presenting cell
- CD4+ T helper cell
- CD8+ Cytotoxic T cell
- Dendritic cell
- B cell
- Antibody
- Positive feedback cycle Positive feedback
- Cytokine
- Monocytes Monocyte
- Natural killer cells Natural killer cell
- Follicular dendritic cells (FDCs) Follicular dendritic cells
- Regulatory T cells Regulatory T cell
- Chondrocytes Chondrocyte
- Neurons Neuron
- Astrocytes Astrocyte
- Microglia
- Endothelial cells Endothelium
Regulation of the immune system
- Pathogen associated molecular patterns (PAMPs) Pathogen-associated molecular pattern
- IL-1 Interleukin-1 family
Atherosclerosis
- Atherosclerosis
- Cardiovascular Disease (CVD) Cardiovascular disease
- Adhesion molecules Adhesion molecule (immunoglobulin-like)
- Intracellular adhesion molecule-1 Intracellular adhesion molecule
- Macrophages Macrophage
- Neutrophils Neutrophil
Interactions
As a drug target
- Monoclonal antibodies (mAbs) Monoclonal antibody
Advanced semantic analysis
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
Map overview Semantic statistics
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.TNFRSF9
Nodes41
Edges40
Triples81
Avg. degree1.95
Density0.04878
Components1
How this topic connects Entity context
Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.See the strongest relationship patterns around the current topic before diving into the raw triples.
TNFRSF9
Top relations
Gene ontology · 20
TNFRSF9 → apoptotic process, apoptotic signaling pathway, cytokine binding, external side of plasma membrane, extracellular space, immune response, inflammatory response, integral component of membrane, integral component of plasma membrane, membrane, multicellular organism development, negative regulation of cell population proliferation, plasma membrane, protein homotrimerization, regulation of apoptotic process, regulation of cell population proliferation, response to lipopolysaccharide, signaling receptor activity, tumor necrosis factor-activated receptor activity, tumor necrosis factor-mediated signaling pathway
Bgee · 18
TNFRSF9 → appendix, blastocyst, blood, buccal mucosa cell, cartilage tissue, decidua, gallbladder, gastrula, granulocyte, islet of Langerhans, lymph node, mesenteric lymph nodes, monocyte, morula, testicle, thymus, uterus, white blood cell
RNA expression pattern · 18
TNFRSF9 → appendix, blastocyst, blood, buccal mucosa cell, cartilage tissue, decidua, gallbladder, gastrula, granulocyte, islet of Langerhans, lymph node, mesenteric lymph nodes, monocyte, morula, testicle, thymus, uterus, white blood cell
Band · 2
TNFRSF9 → 1p36.23, 4 E2|4 81.52 cM
Chr. · 2
TNFRSF9 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
TNFRSF9 → 151,030,559 bp, 7,943,165 bp
related to External links · 2
TNFRSF9 → Human TNFRSF9, UCSC Genome Browser
Aliases · 1
TNFRSF9 → TNFRSF9, 4-1BB, CD137, CDw137, ILA, tumor necrosis factor receptor superfamily member 9, TNF receptor superfamily member 9
Available structures · 1
TNFRSF9 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1D0J
BioGPS · 1
TNFRSF9 → More reference expression data
Important terminology Word statistics
Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
Important terminology
cd137 cells cell immune human bp cancer ligand gene expressed chr band receptor atherosclerosis target proliferation secretion chromosome system immunotherapy
Entity relationships Subject–Predicate–Object triples
Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| TNFRSF9 | Aliases | TNFRSF9, 4-1BB, CD137, CDw137, ILA, tumor necrosis factor receptor superfamily member 9, TNF receptor superfamily member 9 | 1.00 | infobox |
| TNFRSF9 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1D0J | 1.00 | infobox |
| TNFRSF9 | Band | 1p36.23 | 1.00 | infobox |
| TNFRSF9 | Band | 4 E2|4 81.52 cM | 1.00 | infobox |
| TNFRSF9 | Bgee | buccal mucosa cell | 1.00 | infobox |
| TNFRSF9 | Bgee | lymph node | 1.00 | infobox |
| TNFRSF9 | Bgee | cartilage tissue | 1.00 | infobox |
| TNFRSF9 | Bgee | testicle | 1.00 | infobox |
| TNFRSF9 | Bgee | blood | 1.00 | infobox |
| TNFRSF9 | Bgee | appendix | 1.00 | infobox |
| TNFRSF9 | Bgee | white blood cell | 1.00 | infobox |
| TNFRSF9 | Bgee | monocyte | 1.00 | infobox |
| TNFRSF9 | Bgee | granulocyte | 1.00 | infobox |
| TNFRSF9 | Bgee | gallbladder | 1.00 | infobox |
| TNFRSF9 | Bgee | decidua | 1.00 | infobox |
| TNFRSF9 | Bgee | gastrula | 1.00 | infobox |
| TNFRSF9 | Bgee | blastocyst | 1.00 | infobox |
| TNFRSF9 | Bgee | thymus | 1.00 | infobox |
| TNFRSF9 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| TNFRSF9 | Bgee | islet of Langerhans | 1.00 | infobox |
| TNFRSF9 | Bgee | uterus | 1.00 | infobox |
| TNFRSF9 | Bgee | morula | 1.00 | infobox |
| TNFRSF9 | BioGPS | More reference expression data | 1.00 | infobox |
| TNFRSF9 | Chr. | Chromosome 1 (human) | 1.00 | infobox |
| TNFRSF9 | Chr. | Chromosome 4 (mouse) | 1.00 | infobox |
| TNFRSF9 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| TNFRSF9 | End | 7,943,165 bp | 1.00 | infobox |
| TNFRSF9 | End | 151,030,559 bp | 1.00 | infobox |
| TNFRSF9 | Ensembl | ENSG00000049249 | 1.00 | infobox |
| TNFRSF9 | Entrez | 3604 | 1.00 | infobox |
No triples extracted yet.
Related concept clusters Concept neighborhoods
Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.These clusters group vocabulary that occurs around closely connected concepts in the source material.
Connections between topic areas Semantic bridges
Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.
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