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SMARCA2: Interactions, Function & Overview

Probable global transcription activator SNF2L2 is a protein that in humans is encoded by the SMARCA2 gene.

Language: English [EN]
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SMARCA2 topic overview

The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around SMARCA2.

Related topics
23
Source areas
3
Connected nodes
26
Extracted relationships
103
Concept neighborhoods
12
Bridge connections
26

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 11 topics
Function · 10 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SMARCA2, BAF190, BRM, NCBRS, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p, hBRM, hSNF2a, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, BIS
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2DAT, 5DKC, 4QY4
Band
9p24.3 · 19 C1|19 21.17 cM
Bgee
Achilles tendon · epithelium of colon · left ovary · ventricular zone · sural nerve
BioGPS
More reference expression data
Chr.
Chromosome 9 (human) · Chromosome 19 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How SMARCA2 connects Entity context

The extracted context around SMARCA2 shows recurring relationship patterns in the source. For example, SMARCA2 → ATP binding, ATP-dependent activity, acting on DNA, ATPase activity, chromatin binding, chromatin remodeling, DNA binding, helicase activity, histone binding, hydrolase activity, hydrolase activity, acting on acid anhydrides, intermediate filament cytoskeleton, intracellular membrane-bounded organelle, nBAF complex, negative regulation of cell growth, negative regulation of cell population proliferation, negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, nervous system development, npBAF complex, nucleoplasm Another extracted example is SMARCA2 → Achilles tendon, cerebellar cortex, cerebellar vermis, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, dorsomedial hypothalamic nucleus, epithelium of colon, epithelium of nasopharynx, genital tubercle, germinal epithelium, lateral septal nucleus, left ovary, lobe of cerebellum, neural layer of retina, olfactory zone of nasal mucosa, right ovary, secondary oocyte, superior frontal gyrus, sural nerve, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

SMARCA2

Top relations

Gene ontology · 32
SMARCA2 → ATP binding, ATP-dependent activity, acting on DNA, ATPase activity, chromatin binding, chromatin remodeling, DNA binding, helicase activity, histone binding, hydrolase activity, hydrolase activity, acting on acid anhydrides, intermediate filament cytoskeleton, intracellular membrane-bounded organelle, nBAF complex, negative regulation of cell growth, negative regulation of cell population proliferation, negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, nervous system development, npBAF complex, nucleoplasm
Bgee · 20
SMARCA2 → Achilles tendon, cerebellar cortex, cerebellar vermis, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, dorsomedial hypothalamic nucleus, epithelium of colon, epithelium of nasopharynx, genital tubercle, germinal epithelium, lateral septal nucleus, left ovary, lobe of cerebellum, neural layer of retina, olfactory zone of nasal mucosa, right ovary, secondary oocyte, superior frontal gyrus, sural nerve, ventricular zone
RNA expression pattern · 20
SMARCA2 → Achilles tendon, cerebellar cortex, cerebellar vermis, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, dorsomedial hypothalamic nucleus, epithelium of colon, epithelium of nasopharynx, genital tubercle, germinal epithelium, lateral septal nucleus, left ovary, lobe of cerebellum, neural layer of retina, olfactory zone of nasal mucosa, right ovary, secondary oocyte, superior frontal gyrus, sural nerve, ventricular zone
related to Interactions · 8
SMARCA2 → ACTL6A, ARID1B, CEBPB, POLR2A, Prohibitin, SIN3A, SMARCB1, SMARCC1
Band · 2
SMARCA2 → 19 C1|19 21.17 cM, 9p24.3
Chr. · 2
SMARCA2 → Chromosome 19 (mouse), Chromosome 9 (human)
End · 2
SMARCA2 → 2,193,624 bp, 26,755,722 bp
Aliases · 1
SMARCA2 → SMARCA2, BAF190, BRM, NCBRS, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p, hBRM, hSNF2a, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, BIS
Available structures · 1
SMARCA2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2DAT, 5DKC, 4QY4
BioGPS · 1
SMARCA2 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene chr human band chromosome protein chromatin transcription swi snf location encoded mouse snf2l2 function search 193 624 end

SMARCA2 relationships Subject–Predicate–Object triples

TTTA extracted 103 structured relationships around SMARCA2. Examples in this analysis include SMARCA2 → Aliases → SMARCA2, BAF190, BRM, NCBRS, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p, hBRM, hSNF2a, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, BIS and SMARCA2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2DAT, 5DKC, 4QY4. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SMARCA2AliasesSMARCA2, BAF190, BRM, NCBRS, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p, hBRM, hSNF2a, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, BIS1.00infobox
SMARCA2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2DAT, 5DKC, 4QY41.00infobox
SMARCA2Band9p24.31.00infobox
SMARCA2Band19 C1|19 21.17 cM1.00infobox
SMARCA2BgeeAchilles tendon1.00infobox
SMARCA2Bgeeepithelium of colon1.00infobox
SMARCA2Bgeeleft ovary1.00infobox
SMARCA2Bgeeventricular zone1.00infobox
SMARCA2Bgeesural nerve1.00infobox
SMARCA2Bgeeright ovary1.00infobox
SMARCA2Bgeesecondary oocyte1.00infobox
SMARCA2Bgeeolfactory zone of nasal mucosa1.00infobox
SMARCA2Bgeegerminal epithelium1.00infobox
SMARCA2Bgeeepithelium of nasopharynx1.00infobox
SMARCA2Bgeeneural layer of retina1.00infobox
SMARCA2Bgeelateral septal nucleus1.00infobox
SMARCA2Bgeecingulate gyrus1.00infobox
SMARCA2Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
SMARCA2Bgeedorsomedial hypothalamic nucleus1.00infobox
SMARCA2Bgeecerebellar cortex1.00infobox
SMARCA2Bgeesuperior frontal gyrus1.00infobox
SMARCA2Bgeegenital tubercle1.00infobox
SMARCA2Bgeelobe of cerebellum1.00infobox
SMARCA2Bgeecerebellar vermis1.00infobox
SMARCA2BioGPSMore reference expression data1.00infobox
SMARCA2Chr.Chromosome 9 (human)1.00infobox
SMARCA2Chr.Chromosome 19 (mouse)1.00infobox
SMARCA2DatabasesNCBI: entry; OMA: entry1.00infobox
SMARCA2End2,193,624 bp1.00infobox
SMARCA2End26,755,722 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around SMARCA2 bring nearby vocabulary together. In this analysis, examples include Function, Member and Ncbrs. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • SMARCA2
    • Function
    • Member
    • Ncbrs
    • Search
    • Snf2l2
    • Location
    • Snf
    • Swi
    • Transcription
    • Chromatin
    • Chromosome
    • Human
  • smarca2
    • Function
    • Member
    • Ncbrs
    • Search
    • Snf2l2
    • Location
    • Snf
    • Swi
    • Transcription
    • Chromatin
    • Chromosome
    • Human
  • protein
    • Atp-dependent
    • Complex
    • Remodeling
    • Snf
    • Swi
    • Transcription
    • Chromatin
    • Smarca2
    • Atpase
    • C1
    • End
    • Family
  • gene
    • Location
    • Chromosome
    • Human
    • Smarca2
    • Bp
    • Chr
    • C1
    • End
    • Function
    • Member
    • Mouse
    • Search
  • atpase
    • Family
    • Helicase
    • Transcription
    • Chromatin
    • C1
    • Complex
    • End
    • Function
    • Genes
    • Member
    • Mouse
    • Remodeling
  • transcription
    • Atpase
    • Family
    • Helicase
    • Encoded
    • Protein
    • Chromatin
    • Smarca2
    • Activator
    • Gene
    • Global
    • Humans
    • Probable
  • atp-dependent chromatin remodeling
    • Complex
    • Remodeling
    • Snf
    • Swi
    • Encoded
    • Protein
    • Atp-dependent
    • Atpase
    • Chromatin
    • Family
    • Function
    • Genes
  • chromatin
    • Snf
    • Swi
    • Atp-dependent
    • Atpase
    • Complex
    • Family
    • Function
    • Genes
    • Helicase
    • Member
    • Remodeling
    • Search

Connections between topic areas Semantic bridges

For SMARCA2, one of the stronger structural bridges in this analysis connects SMARCA2 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SMARCA2Interactions · splits 15 ⟂ 12
SMARCA2Function · splits 16 ⟂ 11
SMARCA2Overview · splits 24 ⟂ 3

Map overview Semantic statistics

SMARCA2

Nodes27
Edges26
Triples103
Avg. degree1.93
Density0.074074
Components1

Source & methodology

TTTA analyzes the structure around SMARCA2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SMARCA2 · EN edition · Analysis: TopicsToTalkAbout

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