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HMOX1 (heme oxygenase 1 gene) is a human gene that encodes for the enzyme heme oxygenase 1 (EC 1.14.99.3). Heme oxygenase (abbreviated HMOX or HO) mediates the first step of heme catabolism, it cleaves heme to form biliverdin.
The analysis highlights Heme oxygenase, Related conditions and Overview as prominent areas in the source structure around HMOX1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around HMOX1 shows recurring relationship patterns in the source. For example, HMOX1 → angiogenesis, apoptotic process, caveola, cell death, cellular iron ion homeostasis, cellular response to arsenic-containing substance, cellular response to cadmium ion, cellular response to cisplatin, cellular response to heat, cellular response to hypoxia, cellular response to nutrient, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, endothelial cell proliferation, enzyme binding, erythrocyte homeostasis, excretion, extracellular space, heme binding Another extracted example is HMOX1 → calvaria, cartilage tissue, esophagus, gallbladder, granulocyte, islet of Langerhans, left ovary, lens, lip, monocyte, mucosa of transverse colon, placenta, right ovary, skin of leg, spleen, stroma of bone marrow, tibiofemoral joint, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
heme oxygenase human gene bp chromosome 22 chr band enzyme location biliverdin activity hmox mouse 14 external pdb uniprot p09601
TTTA extracted 136 structured relationships around HMOX1. Examples in this analysis include HMOX1 → 1.14.14.18 → ↗ and HMOX1 → Aliases → HMOX1, HMOX1D, HO-1, HSP32, bK286B10, heme oxygenase 1. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| HMOX1 | 1.14.14.18 | ↗ | 1.00 | infobox |
| HMOX1 | Aliases | HMOX1, HMOX1D, HO-1, HSP32, bK286B10, heme oxygenase 1 | 1.00 | infobox |
| HMOX1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1N3U, 1N45, 1NI6, 1OYK, 1OYL, 1OZE, 1OZL, 1OZR, 1OZW, 1S13, 1S8C, 1T5P, 1TWN, 1TWR, 1XJZ, 1XK0, 1XK1, 1XK2,… | 1.00 | infobox |
| HMOX1 | Band | 22q12.3 | 1.00 | infobox |
| HMOX1 | Band | 8 35.59 cM|8 C1 | 1.00 | infobox |
| HMOX1 | Bgee | cartilage tissue | 1.00 | infobox |
| HMOX1 | Bgee | spleen | 1.00 | infobox |
| HMOX1 | Bgee | monocyte | 1.00 | infobox |
| HMOX1 | Bgee | granulocyte | 1.00 | infobox |
| HMOX1 | Bgee | islet of Langerhans | 1.00 | infobox |
| HMOX1 | Bgee | left ovary | 1.00 | infobox |
| HMOX1 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| HMOX1 | Bgee | skin of leg | 1.00 | infobox |
| HMOX1 | Bgee | gallbladder | 1.00 | infobox |
| HMOX1 | Bgee | right ovary | 1.00 | infobox |
| HMOX1 | Bgee | stroma of bone marrow | 1.00 | infobox |
| HMOX1 | Bgee | tibiofemoral joint | 1.00 | infobox |
| HMOX1 | Bgee | lens | 1.00 | infobox |
| HMOX1 | Bgee | lip | 1.00 | infobox |
| HMOX1 | Bgee | esophagus | 1.00 | infobox |
| HMOX1 | Bgee | placenta | 1.00 | infobox |
| HMOX1 | Bgee | calvaria | 1.00 | infobox |
| HMOX1 | Bgee | yolk sac | 1.00 | infobox |
| HMOX1 | BioGPS | More reference expression data | 1.00 | infobox |
| HMOX1 | Chr. | Chromosome 22 (human) | 1.00 | infobox |
| HMOX1 | Chr. | Chromosome 8 (mouse) | 1.00 | infobox |
| HMOX1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| HMOX1 | End | 35,394,214 bp | 1.00 | infobox |
| HMOX1 | End | 75,827,217 bp | 1.00 | infobox |
| HMOX1 | Ensembl | ENSG00000100292 | 1.00 | infobox |
The concept neighborhoods around HMOX1 bring nearby vocabulary together. In this analysis, examples include Enzyme, Gene and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For HMOX1, one of the stronger structural bridges in this analysis connects HMOX1 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around HMOX1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Heme oxygenase, Related conditions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — HMOX1 · EN edition · Analysis: TopicsToTalkAbout