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HMOX1

HMOX1 (heme oxygenase 1 gene) is a human gene that encodes for the enzyme heme oxygenase 1 (EC 1.14.99.3). Heme oxygenase (abbreviated HMOX or HO) mediates the first step of heme catabolism, it cleaves heme to form biliverdin.

Heme oxygenase, Related conditions & Overview

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Heme oxygenase

3 related topics

Related conditions

1 related topics

Overview

7 related topics

Key facts & relationships

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1.14.14.18
Aliases
HMOX1, HMOX1D, HO-1, HSP32, bK286B10, heme oxygenase 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1N3U, 1N45, 1NI6, 1OYK, 1OYL, 1OZE, 1OZL, 1OZR, 1OZW, 1S13, 1S8C, 1T5P, 1TWN, 1TWR, 1XJZ, 1XK0, 1XK1, 1XK2,…
Band
22q12.3 · 8 35.59 cM|8 C1
Bgee
cartilage tissue · spleen · monocyte · granulocyte · islet of Langerhans
BioGPS
More reference expression data

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Overview

Related conditions

Heme oxygenase

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Map overview Semantic statistics

HMOX1

Nodes15
Edges14
Triples136
Avg. degree1.87
Density0.133333
Components1

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HMOX1

Top relations

Gene ontology · 72
HMOX1 → angiogenesis, apoptotic process, caveola, cell death, cellular iron ion homeostasis, cellular response to arsenic-containing substance, cellular response to cadmium ion, cellular response to cisplatin, cellular response to heat, cellular response to hypoxia, cellular response to nutrient, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, endothelial cell proliferation, enzyme binding, erythrocyte homeostasis, excretion, extracellular space, heme binding
Bgee · 18
HMOX1 → calvaria, cartilage tissue, esophagus, gallbladder, granulocyte, islet of Langerhans, left ovary, lens, lip, monocyte, mucosa of transverse colon, placenta, right ovary, skin of leg, spleen, stroma of bone marrow, tibiofemoral joint, yolk sac
RNA expression pattern · 18
HMOX1 → calvaria, cartilage tissue, esophagus, gallbladder, granulocyte, islet of Langerhans, left ovary, lens, lip, monocyte, mucosa of transverse colon, placenta, right ovary, skin of leg, spleen, stroma of bone marrow, tibiofemoral joint, yolk sac
related to Heme oxygenase · 3
HMOX1 → Heme, HMOX2, The
Band · 2
HMOX1 → 22q12.3, 8 35.59 cM|8 C1
Chr. · 2
HMOX1 → Chromosome 22 (human), Chromosome 8 (mouse)
End · 2
HMOX1 → 35,394,214 bp, 75,827,217 bp
1.14.14.18 · 1
HMOX1 → ↗
Aliases · 1
HMOX1 → HMOX1, HMOX1D, HO-1, HSP32, bK286B10, heme oxygenase 1
Available structures · 1
HMOX1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1N3U, 1N45, 1NI6, 1OYK, 1OYL, 1OZE, 1OZL, 1OZR, 1OZW, 1S13, 1S8C, 1T5P, 1TWN, 1TWR, 1XJZ, 1XK0, 1XK1, 1XK2,…

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Important terminology

heme oxygenase human gene bp chromosome 22 chr band enzyme location biliverdin activity hmox mouse 14 external pdb uniprot p09601

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
HMOX11.14.14.181.00infobox
HMOX1AliasesHMOX1, HMOX1D, HO-1, HSP32, bK286B10, heme oxygenase 11.00infobox
HMOX1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1N3U, 1N45, 1NI6, 1OYK, 1OYL, 1OZE, 1OZL, 1OZR, 1OZW, 1S13, 1S8C, 1T5P, 1TWN, 1TWR, 1XJZ, 1XK0, 1XK1, 1XK2,…1.00infobox
HMOX1Band22q12.31.00infobox
HMOX1Band8 35.59 cM|8 C11.00infobox
HMOX1Bgeecartilage tissue1.00infobox
HMOX1Bgeespleen1.00infobox
HMOX1Bgeemonocyte1.00infobox
HMOX1Bgeegranulocyte1.00infobox
HMOX1Bgeeislet of Langerhans1.00infobox
HMOX1Bgeeleft ovary1.00infobox
HMOX1Bgeemucosa of transverse colon1.00infobox
HMOX1Bgeeskin of leg1.00infobox
HMOX1Bgeegallbladder1.00infobox
HMOX1Bgeeright ovary1.00infobox
HMOX1Bgeestroma of bone marrow1.00infobox
HMOX1Bgeetibiofemoral joint1.00infobox
HMOX1Bgeelens1.00infobox
HMOX1Bgeelip1.00infobox
HMOX1Bgeeesophagus1.00infobox
HMOX1Bgeeplacenta1.00infobox
HMOX1Bgeecalvaria1.00infobox
HMOX1Bgeeyolk sac1.00infobox
HMOX1BioGPSMore reference expression data1.00infobox
HMOX1Chr.Chromosome 22 (human)1.00infobox
HMOX1Chr.Chromosome 8 (mouse)1.00infobox
HMOX1DatabasesNCBI: entry; OMA: entry1.00infobox
HMOX1End35,394,214 bp1.00infobox
HMOX1End75,827,217 bp1.00infobox
HMOX1EnsemblENSG000001002921.00infobox

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