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Serine/threonine kinase 11 (STK11) also known as liver kinase B1 (LKB1) or renal carcinoma antigen NY-REN-19 is a protein kinase that in humans is encoded by the STK11 gene.
The analysis highlights Function, Expression and Clinical significance as prominent areas in the source structure around STK11.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around STK11 shows recurring relationship patterns in the source. For example, STK11 → activation of protein kinase activity, anoikis, apoptotic process, ATP binding, autophagy, axonogenesis, canonical Wnt signaling pathway, cell cycle, cell differentiation, cellular response to DNA damage stimulus, cellular response to UV-B, cytoplasm, cytosol, dendrite extension, establishment of cell polarity, extracellular exosome, glucose homeostasis, Golgi localization, intrinsic apoptotic signaling pathway by p53 class mediator, kinase activity Another extracted example is STK11 → apex of heart, gastrocnemius muscle, granulocyte, Ileal epithelium, left testis, lip, mucosa of transverse colon, muscle of thigh, neural layer of retina, otic placode, right hemisphere of cerebellum, right testis, saccule, stromal cell of endometrium, tendon of biceps brachii, ventricular zone, yolk sac, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
lkb1 gene kinase ampk bp protein human expression activation chr band activity cell serine threonine chromosome 19 growth splice kinases
TTTA extracted 148 structured relationships around STK11. Examples in this analysis include STK11 → 2.7.11.1 → ↗ and STK11 → Aliases → STK11, LKB1, PJS, hLKB1, serine/threonine kinase 11. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| STK11 | 2.7.11.1 | ↗ | 1.00 | infobox |
| STK11 | Aliases | STK11, LKB1, PJS, hLKB1, serine/threonine kinase 11 | 1.00 | infobox |
| STK11 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2WTK, 4ZDR | 1.00 | infobox |
| STK11 | Band | 19p13.3 | 1.00 | infobox |
| STK11 | Band | 10|10 C1 | 1.00 | infobox |
| STK11 | Bgee | left testis | 1.00 | infobox |
| STK11 | Bgee | right testis | 1.00 | infobox |
| STK11 | Bgee | muscle of thigh | 1.00 | infobox |
| STK11 | Bgee | gastrocnemius muscle | 1.00 | infobox |
| STK11 | Bgee | granulocyte | 1.00 | infobox |
| STK11 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| STK11 | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| STK11 | Bgee | tendon of biceps brachii | 1.00 | infobox |
| STK11 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| STK11 | Bgee | apex of heart | 1.00 | infobox |
| STK11 | Bgee | Ileal epithelium | 1.00 | infobox |
| STK11 | Bgee | saccule | 1.00 | infobox |
| STK11 | Bgee | ventricular zone | 1.00 | infobox |
| STK11 | Bgee | otic placode | 1.00 | infobox |
| STK11 | Bgee | neural layer of retina | 1.00 | infobox |
| STK11 | Bgee | lip | 1.00 | infobox |
| STK11 | Bgee | zygote | 1.00 | infobox |
| STK11 | Bgee | yolk sac | 1.00 | infobox |
| STK11 | BioGPS | More reference expression data | 1.00 | infobox |
| STK11 | Chr. | Chromosome 19 (human) | 1.00 | infobox |
| STK11 | Chr. | Chromosome 10 (mouse) | 1.00 | infobox |
| STK11 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| STK11 | End | 1,228,431 bp | 1.00 | infobox |
| STK11 | End | 79,966,516 bp | 1.00 | infobox |
| STK11 | Ensembl | ENSG00000118046 | 1.00 | infobox |
The concept neighborhoods around STK11 bring nearby vocabulary together. In this analysis, examples include Threonine, Decreased and Activity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For STK11, one of the stronger structural bridges in this analysis connects STK11 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around STK11 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Expression & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — STK11 · EN edition · Analysis: TopicsToTalkAbout