STAT2

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STAT2 topic overview

The analysis highlights Interactions, Function and STAT2 deficiency as prominent areas in the source structure around STAT2.

Related topics: 21
Source areas: 4
Connected nodes: 25
Extracted relationships: 149
Concept neighborhoods: 12
Bridge connections: 25

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 10 topics

Interactions · 7 topics

Function · 3 topics

STAT2 deficiency · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: STAT2, ISGF-3, P113, STAT113, IMD44, signal transducer and activator of transcription 2, PTORCH3
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KA4
Band: 12q13.3 · 10 D3|10 76.5 cM
Bgee: granulocyte · stromal cell of endometrium · monocyte · sural nerve · pituitary gland
BioGPS: More reference expression data
Chr.: Chromosome 12 (human) · Chromosome 10 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Protein
Gene
STAT protein
Transcription factor
MMR MMR vaccine
RSV Respiratory syncytial virus
Norovirus
Coxsackievirus
Adenovirus Adenovirus infection
Enterovirus

Function

Cytokines
IFN Interferon
IRF9

Interactions

STAT2 deficiency

Knockout Knockout mice

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How STAT2 connects Entity context

The extracted context around STAT2 shows recurring relationship patterns in the source. For example, STAT2 → cytokine-mediated signaling pathway, cytoplasm, cytosol, defense response, defense response to virus, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, identical protein binding, nucleoplasm, nucleus, plasma membrane, positive regulation of transcription by RNA polymerase II, protein binding, receptor signaling pathway via JAK-STAT, regulation of cell population proliferation, regulation of mitochondrial fission, regulation of protein phosphorylation, regulation of transcription by RNA polymerase II Another extracted example is STAT2 → DNA, EP300/CREBBP, IFN, IFN-alpha, IFN-stimulated, IFN-α, Immunodeficiency, In, IRF9, ISGF-3, ISRE, ISRE-driven, Ly-6C, MHC, Mutations, MX, OAS, P300/CBP, PKR, RNA. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 29

STAT2 → cytokine-mediated signaling pathway, cytoplasm, cytosol, defense response, defense response to virus, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, identical protein binding, nucleoplasm, nucleus, plasma membrane, positive regulation of transcription by RNA polymerase II, protein binding, receptor signaling pathway via JAK-STAT, regulation of cell population proliferation, regulation of mitochondrial fission, regulation of protein phosphorylation, regulation of transcription by RNA polymerase II

related to Function · 25

STAT2 → DNA, EP300/CREBBP, IFN, IFN-alpha, IFN-stimulated, IFN-α, Immunodeficiency, In, IRF9, ISGF-3, ISRE, ISRE-driven, Ly-6C, MHC, Mutations, MX, OAS, P300/CBP, PKR, RNA

related to Knockout mice · 21

STAT2 → Additionally, Arginase-1, DNV, IFN-α, IFN-γ, In, Indiana, M1, M1/M2, M2, MCMV, STAT, STAT1, The, Therefore, These, This, Vesicular, VSV, WT

Bgee · 19

STAT2 → anterior pituitary, canal of the cervix, cerebellar cortex, epithelium of small intestine, genital tubercle, granulocyte, lumbar spinal ganglion, monocyte, mucous cell of stomach, neural layer of retina, pituitary gland, right lobe of liver, right ovary, stromal cell of endometrium, superior frontal gyrus, sural nerve, tendon of biceps brachii, thymus, zygote

RNA expression pattern · 19

related to External links · 8

STAT2 → Factor, FactorBookSTAT2 This, Medicine, Medicine Medical Subject Headings, MeSH, National Library, Transcription, United States National Library

related to Interactions · 5

STAT2 → CREB-binding, IFNAR1IFNAR2, IRF9, MED14, SMARCA4

Band · 2

STAT2 → 10 D3|10 76.5 cM, 12q13.3

Chr. · 2

STAT2 → Chromosome 10 (mouse), Chromosome 12 (human)

End · 2

STAT2 → 128,128,718 bp, 56,360,167 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein human response gene type viral transcription knockout patients bp deficiency mice infection ifn chr band ar mouse infections chromosome

STAT2 relationships Subject–Predicate–Object triples

TTTA extracted 149 structured relationships around STAT2. Examples in this analysis include STAT2 → Aliases → STAT2, ISGF-3, P113, STAT113, IMD44, signal transducer and activator of transcription 2, PTORCH3 and STAT2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KA4. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
STAT2	Aliases	STAT2, ISGF-3, P113, STAT113, IMD44, signal transducer and activator of transcription 2, PTORCH3	1.00	infobox
STAT2	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KA4	1.00	infobox
STAT2	Band	12q13.3	1.00	infobox
STAT2	Band	10 D3\|10 76.5 cM	1.00	infobox
STAT2	Bgee	granulocyte	1.00	infobox
STAT2	Bgee	stromal cell of endometrium	1.00	infobox
STAT2	Bgee	monocyte	1.00	infobox
STAT2	Bgee	sural nerve	1.00	infobox
STAT2	Bgee	pituitary gland	1.00	infobox
STAT2	Bgee	anterior pituitary	1.00	infobox
STAT2	Bgee	right ovary	1.00	infobox
STAT2	Bgee	right lobe of liver	1.00	infobox
STAT2	Bgee	tendon of biceps brachii	1.00	infobox
STAT2	Bgee	canal of the cervix	1.00	infobox
STAT2	Bgee	lumbar spinal ganglion	1.00	infobox
STAT2	Bgee	neural layer of retina	1.00	infobox
STAT2	Bgee	epithelium of small intestine	1.00	infobox
STAT2	Bgee	cerebellar cortex	1.00	infobox
STAT2	Bgee	thymus	1.00	infobox
STAT2	Bgee	zygote	1.00	infobox
STAT2	Bgee	genital tubercle	1.00	infobox
STAT2	Bgee	mucous cell of stomach	1.00	infobox
STAT2	Bgee	superior frontal gyrus	1.00	infobox
STAT2	BioGPS	More reference expression data	1.00	infobox
STAT2	Chr.	Chromosome 12 (human)	1.00	infobox
STAT2	Chr.	Chromosome 10 (mouse)	1.00	infobox
STAT2	Databases	NCBI: entry; OMA: entry	1.00	infobox
STAT2	End	56,360,167 bp	1.00	infobox
STAT2	End	128,128,718 bp	1.00	infobox
STAT2	Ensembl	ENSG00000170581	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around STAT2 bring nearby vocabulary together. In this analysis, examples include Knockout, Deficiency and Mice. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

STAT2
- Knockout
- Deficiency
- Mice
- Ar
- Double
- Transcription
- Patients
- Type
- Viral
- Function
- Transducer
- Could
stat2
- Knockout
- Deficiency
- Mice
- Ar
- Double
- Transcription
- Patients
- Type
- Viral
- Function
- Transducer
- Could
gene
- Location
- Signal
- Transducer
- Chromosome
- Bp
- Chr
- Human
- Transcription
- Protein
- Function
- Band
- Factor
stat protein
- Family
- Virus
- Response
- Transcription
- Gene
- Biological
- Signal
- Transducer
- Factor
- Stat
- Stat1
- Type
transcription factor
- Transducer
- Factor
- Transcription
- Family
- Function
- Location
- Chromosome
- Stat
- Bp
- Chr
- Gene
- Protein
stat2 deficiency
- Ar
- Knockout
- Deficiency
- Stat2
- Mice
- Patients
- Could
- Double
- Phenotype
- Transcription
- Human
- Type
protein
- Family
- Response
- Transcription
- Gene
- Biological
- Signal
- Transducer
- Factor
- Stat
- Stat1
- Type
- Stat2
creb-binding protein
- Family
- Response
- Transcription
- Gene
- Biological
- Signal
- Transducer
- Factor
- Stat
- Stat1
- Type
- Stat2

Connections between topic areas Semantic bridges

For STAT2, one of the stronger structural bridges in this analysis connects STAT2 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

STAT2 — Overview · splits 15 ⟂ 11

STAT2 — Interactions · splits 18 ⟂ 8

STAT2 — Function · splits 22 ⟂ 4

Map overview Semantic statistics

STAT2

Nodes26

Edges25

Triples149

Avg. degree1.92

Density0.076923

Components1

Source & methodology

TTTA analyzes the structure around STAT2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & STAT2 deficiency, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — STAT2 · EN edition · Analysis: TopicsToTalkAbout