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OB-fold: Art, Structure & Function

In molecular biology, the OB-fold (oligonucleotide/oligosaccharide-binding fold) is a small protein structural motif observed in different proteins that bind oligonucleotides or oligosaccharides. It was originally identified in 1993 in four unrelated proteins: staphylococcal nuclease, anticodon binding domain of aspartyl-tRNA synthetase, and the…

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OB-fold topic overview

The analysis highlights Art, Structure and Function as prominent areas in the source structure around OB-fold.

Related topics
27
Source areas
6
Connected nodes
33
Extracted relationships
28
Concept neighborhoods
24
Bridge connections
33

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 8 topics
Structure · 8 topics
Examples of proteins containing this domain · 4 topics
Overview · 4 topics
Evolution and distribution · 2 topics
Relationship to SH3 domains · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR012340
Available protein structures:
IPR012340
ECOD
2
InterPro
IPR012340
PDB
IPR012340
Pfam clan
CL0021

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Examples of proteins containing this domain

Relationship to SH3 domains

Evolution and distribution

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How OB-fold connects Entity context

The extracted context around OB-fold shows recurring relationship patterns in the source. For example, OB-fold → In, Its, OB-folds, SH3, The OB-fold, They Another extracted example is OB-fold → OB-folds, PXXP-containing, SH3, Src, This. Use these groups to spot repeated connection types before inspecting the individual relationships.

OB-fold

Top relations

related to Evolution and distribution · 6
OB-fold → In, Its, OB-folds, SH3, The OB-fold, They
related to Relationship to SH3 domains · 5
OB-fold → OB-folds, PXXP-containing, SH3, Src, This
related to Function · 4
OB-fold → DNA, In, OB-folds, RNA
related to External links · 3
OB-fold → InterPro, IPR012340, Nucleic
related to Structure · 2
OB-fold → The, The OB-fold
AlphaFold · 1
OB-fold → IPR012340
Available protein structures: · 1
OB-fold → IPR012340
ECOD · 1
OB-fold → 2
InterPro · 1
OB-fold → IPR012340
PDB · 1
OB-fold → IPR012340

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

proteins binding structure domains structural protein β-sheet barrel ob-folds fold motif sh3 dna functions different many genome β-barrel domain oligosaccharides

OB-fold relationships Subject–Predicate–Object triples

TTTA extracted 28 structured relationships around OB-fold. Examples in this analysis include OB-fold → AlphaFold → IPR012340 and OB-fold → ECOD → 2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
OB-foldAlphaFoldIPR0123401.00infobox
OB-foldAvailable protein structures:IPR0123401.00infobox
OB-foldECOD21.00infobox
OB-foldInterProIPR0123401.00infobox
OB-foldPDBIPR0123401.00infobox
OB-foldPfam clanCL00211.00infobox
OB-foldSymbolOB-fold1.00infobox
OB-foldrelated to Evolution and distributionThe OB-fold0.60section
OB-foldrelated to Evolution and distributionThey0.60section
OB-foldrelated to Evolution and distributionIn0.60section
OB-foldrelated to Evolution and distributionIts0.60section
OB-foldrelated to Evolution and distributionSH30.60section

Related concept clusters Concept neighborhoods

The concept neighborhoods around OB-fold bring nearby vocabulary together. In this analysis, examples include Structural, Different and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • OB-fold
    • Structural
    • Different
    • Protein
    • Binding
    • Domains
    • Bind
    • Determinants
    • Evolution
    • Function
    • Interpro
    • Ipr012340
    • Motif
  • ob-fold
    • Structural
    • Different
    • Protein
    • Binding
    • Domains
    • Bind
    • Determinants
    • Evolution
    • Function
    • Interpro
    • Ipr012340
    • Motif
  • protein structural motif
    • Domains
    • Different
    • Sh3
    • Determinants
    • Evolution
    • Function
    • Small
    • Closed
    • Protein
    • Single-stranded
    • Structures
    • Β-strands
  • protein structure
    • Β-sheet
    • Closed
    • Evolution
    • Layer
    • Small
    • Structures
    • Β-barrel
    • Single-stranded
    • Β-strands
    • Dna
    • Sh3
    • Structure
  • binding sites
    • Proteins
    • Dna
    • Ob-folds
    • Domains
    • Single-stranded
    • Functions
    • Ob-fold
    • Sh3
    • Catalytic
    • Domain
    • Function
    • Β-barrel
  • binding domains
    • Sh3
    • Ob-folds
    • Structural
    • Single-stranded
    • Dna
    • Proteins
    • Function
    • Domains
    • Complex
    • Functions
    • Ob-fold
    • Protein
  • single-stranded dna
    • Dna
    • Single-stranded
    • Ob-folds
    • Proteins
    • Domains
    • Sh3
    • Protein
    • Interpro
    • Ipr012340
    • Α-helix
    • Catalytic
    • Closed
  • double-stranded dna
    • Single-stranded
    • Ob-folds
    • Proteins
    • Domains
    • Sh3
    • Protein
    • Catalytic
    • Domain
    • Evolution
    • Function
    • Interpro
    • Ipr012340

Connections between topic areas Semantic bridges

For OB-fold, one of the stronger structural bridges in this analysis connects OB-fold with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
OB-fold — Structure · splits 25 ⟂ 9
OB-fold — Function · splits 25 ⟂ 9
OB-fold — Overview · splits 29 ⟂ 5
OB-fold — Examples of proteins containing this domain · splits 29 ⟂ 5
OB-fold — Evolution and distribution · splits 31 ⟂ 3

Map overview Semantic statistics

OB-fold

Nodes34
Edges33
Triples28
Avg. degree1.94
Density0.058824
Components1

Source & methodology

TTTA analyzes the structure around OB-fold to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Structure & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — OB-fold · EN edition · Analysis: TopicsToTalkAbout

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