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SHFM1

26S proteasome complex subunit DSS1 is a protein that in humans is encoded by the SHFM1 gene.

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2 related topics

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Aliases
SEM1, DSS1, ECD, SHFD1, SHSF1, Shfdg1, SHFM1, split hand/foot malformation (ectrodactyly) type 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IYJ, 1MIU, 1MJE, 3T5X
Band
6|6 A1
Bgee
mandibular prominence · maxillary prominence · endothelial cell of lymphatic vessel · medullary collecting duct · body of femur
BioGPS
More reference expression data
Chr.
Chromosome 6 (mouse)

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Map overview Semantic statistics

SHFM1

Nodes7
Edges6
Triples77
Avg. degree1.71
Density0.285714
Components1

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SHFM1

Top relations

Gene ontology · 33
SHFM1 → anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, cytosol, double-strand break repair via homologous recombination, Fc-epsilon receptor signaling pathway, integrator complex, interleukin-1-mediated signaling pathway, MAPK cascade, mRNA export from nucleus, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, NIK/NF-kappaB signaling, nucleoplasm, positive regulation of canonical Wnt signaling pathway, post-translational protein modification, proteasome assembly, proteasome complex, proteasome regulatory particle, lid subcomplex, proteasome-mediated ubiquitin-dependent protein catabolic process, protein binding
Bgee · 10
SHFM1 → abdominal wall, body of femur, dermis, endothelial cell of lymphatic vessel, hair follicle, mandibular prominence, maxillary prominence, medial ganglionic eminence, medullary collecting duct, primitive streak
RNA expression pattern · 10
SHFM1 → abdominal wall, body of femur, dermis, endothelial cell of lymphatic vessel, hair follicle, mandibular prominence, maxillary prominence, medial ganglionic eminence, medullary collecting duct, primitive streak
related to Function · 4
SHFM1 → BRCA2, In, It, The
Aliases · 1
SHFM1 → SEM1, DSS1, ECD, SHFD1, SHSF1, Shfdg1, SHFM1, split hand/foot malformation (ectrodactyly) type 1
Available structures · 1
SHFM1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IYJ, 1MIU, 1MJE, 3T5X
Band · 1
SHFM1 → 6|6 A1
BioGPS · 1
SHFM1 → More reference expression data
Chr. · 1
SHFM1 → Chromosome 6 (mouse)
Databases · 1
SHFM1 → NCBI: entry; OMA: entry

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Important terminology

gene bp chr chromosome protein sem1 mouse band split hand foot malformation proteasome complex dss1 function search location 578 663

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SHFM1AliasesSEM1, DSS1, ECD, SHFD1, SHSF1, Shfdg1, SHFM1, split hand/foot malformation (ectrodactyly) type 11.00infobox
SHFM1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IYJ, 1MIU, 1MJE, 3T5X1.00infobox
SHFM1Band6|6 A11.00infobox
SHFM1Bgeemandibular prominence1.00infobox
SHFM1Bgeemaxillary prominence1.00infobox
SHFM1Bgeeendothelial cell of lymphatic vessel1.00infobox
SHFM1Bgeemedullary collecting duct1.00infobox
SHFM1Bgeebody of femur1.00infobox
SHFM1Bgeemedial ganglionic eminence1.00infobox
SHFM1Bgeehair follicle1.00infobox
SHFM1Bgeeprimitive streak1.00infobox
SHFM1Bgeeabdominal wall1.00infobox
SHFM1Bgeedermis1.00infobox
SHFM1BioGPSMore reference expression data1.00infobox
SHFM1Chr.Chromosome 6 (mouse)1.00infobox
SHFM1DatabasesNCBI: entry; OMA: entry1.00infobox
SHFM1End6,578,663 bp1.00infobox
SHFM1EnsemblENSG000001279221.00infobox
SHFM1Entrez79791.00infobox
SHFM1External IDsOMIM: 601285; MGI: 109238; GeneCards: SEM11.00infobox
SHFM1Gene location (Mouse)Gene location (Mouse)Chr.Chromosome 6 (mouse)Band6|6 A1Start6,557,294 bpEnd6,578,663 bp1.00infobox
SHFM1Gene ontologyprotein binding1.00infobox
SHFM1Gene ontologyintegrator complex1.00infobox
SHFM1Gene ontologyproteasome complex1.00infobox
SHFM1Gene ontologyproteasome regulatory particle, lid subcomplex1.00infobox
SHFM1Gene ontologynucleoplasm1.00infobox
SHFM1Gene ontologycytosol1.00infobox
SHFM1Gene ontologymRNA export from nucleus1.00infobox
SHFM1Gene ontologyproteasome assembly1.00infobox
SHFM1Gene ontologyprotein deubiquitination1.00infobox

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