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26S proteasome complex subunit DSS1 is a protein that in humans is encoded by the SHFM1 gene.
The analysis highlights Measurement, Interactions and Overview as prominent areas in the source structure around SHFM1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around SHFM1 shows recurring relationship patterns in the source. For example, SHFM1 → anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, cytosol, double-strand break repair via homologous recombination, Fc-epsilon receptor signaling pathway, integrator complex, interleukin-1-mediated signaling pathway, MAPK cascade, mRNA export from nucleus, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, NIK/NF-kappaB signaling, nucleoplasm, positive regulation of canonical Wnt signaling pathway, post-translational protein modification, proteasome assembly, proteasome complex, proteasome regulatory particle, lid subcomplex, proteasome-mediated ubiquitin-dependent protein catabolic process, protein binding Another extracted example is SHFM1 → abdominal wall, body of femur, dermis, endothelial cell of lymphatic vessel, hair follicle, mandibular prominence, maxillary prominence, medial ganglionic eminence, medullary collecting duct, primitive streak. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
gene bp chr chromosome protein sem1 mouse band split hand foot malformation proteasome complex dss1 function search location 578 663
TTTA extracted 77 structured relationships around SHFM1. Examples in this analysis include SHFM1 → Aliases → SEM1, DSS1, ECD, SHFD1, SHSF1, Shfdg1, SHFM1, split hand/foot malformation (ectrodactyly) type 1 and SHFM1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IYJ, 1MIU, 1MJE, 3T5X. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| SHFM1 | Aliases | SEM1, DSS1, ECD, SHFD1, SHSF1, Shfdg1, SHFM1, split hand/foot malformation (ectrodactyly) type 1 | 1.00 | infobox |
| SHFM1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IYJ, 1MIU, 1MJE, 3T5X | 1.00 | infobox |
| SHFM1 | Band | 6|6 A1 | 1.00 | infobox |
| SHFM1 | Bgee | mandibular prominence | 1.00 | infobox |
| SHFM1 | Bgee | maxillary prominence | 1.00 | infobox |
| SHFM1 | Bgee | endothelial cell of lymphatic vessel | 1.00 | infobox |
| SHFM1 | Bgee | medullary collecting duct | 1.00 | infobox |
| SHFM1 | Bgee | body of femur | 1.00 | infobox |
| SHFM1 | Bgee | medial ganglionic eminence | 1.00 | infobox |
| SHFM1 | Bgee | hair follicle | 1.00 | infobox |
| SHFM1 | Bgee | primitive streak | 1.00 | infobox |
| SHFM1 | Bgee | abdominal wall | 1.00 | infobox |
| SHFM1 | Bgee | dermis | 1.00 | infobox |
| SHFM1 | BioGPS | More reference expression data | 1.00 | infobox |
| SHFM1 | Chr. | Chromosome 6 (mouse) | 1.00 | infobox |
| SHFM1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| SHFM1 | End | 6,578,663 bp | 1.00 | infobox |
| SHFM1 | Ensembl | ENSG00000127922 | 1.00 | infobox |
| SHFM1 | Entrez | 7979 | 1.00 | infobox |
| SHFM1 | External IDs | OMIM: 601285; MGI: 109238; GeneCards: SEM1 | 1.00 | infobox |
| SHFM1 | Gene location (Mouse) | Gene location (Mouse)Chr.Chromosome 6 (mouse)Band6|6 A1Start6,557,294 bpEnd6,578,663 bp | 1.00 | infobox |
| SHFM1 | Gene ontology | protein binding | 1.00 | infobox |
| SHFM1 | Gene ontology | integrator complex | 1.00 | infobox |
| SHFM1 | Gene ontology | proteasome complex | 1.00 | infobox |
| SHFM1 | Gene ontology | proteasome regulatory particle, lid subcomplex | 1.00 | infobox |
| SHFM1 | Gene ontology | nucleoplasm | 1.00 | infobox |
| SHFM1 | Gene ontology | cytosol | 1.00 | infobox |
| SHFM1 | Gene ontology | mRNA export from nucleus | 1.00 | infobox |
| SHFM1 | Gene ontology | proteasome assembly | 1.00 | infobox |
| SHFM1 | Gene ontology | protein deubiquitination | 1.00 | infobox |
The concept neighborhoods around SHFM1 bring nearby vocabulary together. In this analysis, examples include Chromosome, Function and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For SHFM1, one of the stronger structural bridges in this analysis connects SHFM1 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around SHFM1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — SHFM1 · EN edition · Analysis: TopicsToTalkAbout