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Mycophenolic acid

Mycophenolic acid is an immunosuppressant medication used to prevent rejection following organ transplantation and to treat autoimmune conditions such as Crohn's disease, lupus and myasthenia gravis. Specifically it is used following kidney, heart, and liver transplantation. It can be given by mouth or by injection into a vein. It comes as mycophenolate…

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3D model (JSmol)
mycophenolic acid: Interactive image · mofetil ester: Interactive image
AHFS/Drugs.com
Monograph
ATC code
mycophenolic acid: L04AA06 (WHO)
Bioavailability
72% (sodium), 94% (mofetil)
CAS Number
mycophenolic acid: 24280-93-1 Y 128794-94-5 (mofetil ester),37415-62-6 (sodium salt)
ChEBI
mycophenolic acid: CHEBI:168396 Y

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Pharmacology

Chemistry

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Mycophenolic acid

Nodes115
Edges114
Triples97
Avg. degree1.98
Density0.017391
Components1

How this topic connects Entity context

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Mycophenolic acid

Top relations

related to history · 35
Mycophenolic acid → After, Allison, Allisons, Alsberg, Although, American, Anthony Allison, Bartolomeo Gosio, Black, But, Cellcept, Drug Administration, Elsie, Eugui, European Union, February, Food, Gosio, He, However
related to Mechanism of action · 8
Mycophenolic acid → DNA, GMP, IMP, IMPDH, In, Mycophenolic, Purines, Thus
Legal status · 6
Mycophenolic acid → AU: S4 (Prescription only), CA: ℞-only, EU: Rx-only, In general: ℞ (Prescription only), UK: POM (Prescription only), US: ℞-only
related to Pharmacology · 4
Mycophenolic acid → It, Mycophenolate, Other, Penicillium
3D model (JSmol) · 2
Mycophenolic acid → mofetil ester: Interactive image, mycophenolic acid: Interactive image
is a · 2
Mycophenolic acid → immunosuppressant medication used to prevent rejection following organ transplantation and to treat autoimmune conditions such as Crohn's disease, potent
related to Comparison to other agents · 2
Mycophenolic acid → Compared, Mycophenolic
AHFS/Drugs.com · 1
Mycophenolic acid → Monograph
ATC code · 1
Mycophenolic acid → mycophenolic acid: L04AA06 (WHO)
Bioavailability · 1
Mycophenolic acid → 72% (sodium), 94% (mofetil)

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Important terminology

mycophenolate used mofetil mycophenolic acid effects also sodium use organ drug transplantation liver rejection people adverse autoimmune kidney pregnancy compound

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Mycophenolic acid3D model (JSmol)mycophenolic acid: Interactive image1.00infobox
Mycophenolic acid3D model (JSmol)mofetil ester: Interactive image1.00infobox
Mycophenolic acidAHFS/Drugs.comMonograph1.00infobox
Mycophenolic acidATC codemycophenolic acid: L04AA06 (WHO)1.00infobox
Mycophenolic acidBioavailability72% (sodium), 94% (mofetil)1.00infobox
Mycophenolic acidCAS Numbermycophenolic acid: 24280-93-1 Y 128794-94-5 (mofetil ester),37415-62-6 (sodium salt)1.00infobox
Mycophenolic acidChEBImycophenolic acid: CHEBI:168396 Y1.00infobox
Mycophenolic acidChEMBLmycophenolic acid: ChEMBL866 Y1.00infobox
Mycophenolic acidChemSpidermycophenolic acid: 393865 Y1.00infobox
Mycophenolic acidCompTox Dashboard (EPA)mycophenolic acid: DTXSID40410701.00infobox
Mycophenolic acidDrugBankmycophenolic acid: DB01024 Y1.00infobox
Mycophenolic acidECHA InfoCard100.041.9121.00infobox
Mycophenolic acidElimination half-life17.9±6.5 hours1.00infobox
Mycophenolic acidExcretionUrine (93%), faeces (6%)1.00infobox
Mycophenolic acidFormulaC17H20O61.00infobox
Mycophenolic acidIUPHAR/BPSmycophenolic acid: 68321.00infobox
Mycophenolic acidKEGGmycophenolic acid: D05096 Y1.00infobox
Mycophenolic acidLegal statusAU: S4 (Prescription only)1.00infobox
Mycophenolic acidLegal statusCA: ℞-only1.00infobox
Mycophenolic acidLegal statusUK: POM (Prescription only)1.00infobox
Mycophenolic acidLegal statusUS: ℞-only1.00infobox
Mycophenolic acidLegal statusEU: Rx-only1.00infobox
Mycophenolic acidLegal statusIn general: ℞ (Prescription only)1.00infobox
Mycophenolic acidLicense dataUS DailyMed: Mycophenolate mofetil1.00infobox
Mycophenolic acidMedlinePlusa6010811.00infobox
Mycophenolic acidMelting point141 °C (286 °F)1.00infobox
Mycophenolic acidMetabolismLiver1.00infobox
Mycophenolic acidMolar mass320.341 g·mol−11.00infobox
Mycophenolic acidOther namesMPA, Mycophenolate sodium, Mycophenolate mofetil (AAN AU), Mycophenolate mofetil (USAN US)1.00infobox
Mycophenolic acidPregnancy categoryAU: D1.00infobox

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