Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Erlotinib: Community, Culture, Applications & Art

Erlotinib, sold under the brand name Tarceva among others, is a medication used to treat non-small cell lung cancer (NSCLC) and pancreatic cancer. Specifically it is used for NSCLC with mutations in the epidermal growth factor receptor (EGFR) — either an exon 19 deletion (del19) or exon 21 (L858R) substitution mutation — which has spread to other parts…

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

Erlotinib topic overview

The analysis highlights Community, Culture, Applications and Art as prominent areas in the source structure around Erlotinib.

Related topics
54
Source areas
6
Connected nodes
60
Extracted relationships
85
Concept neighborhoods
21
Bridge connections
60

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 14 topics
Side effects · 14 topics
Medical uses · 13 topics
Mechanism · 6 topics
Society and culture · 4 topics
Interactions · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
L01EB02 (WHO)
Bioavailability
59%
CAS Number
183321-74-6 Y
ChEBI
CHEBI:114785 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Side effects

Interactions

Mechanism

Society and culture

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Erlotinib connects Entity context

The extracted context around Erlotinib shows recurring relationship patterns in the source. For example, Erlotinib → Cipla, Delaware, Genentech, In India, In May, Indian, It, Mylan Pharmaceuticals, OSI Pharmaceutical LLC, OSI Pharmaceuticals, Roche, The, United States, US District Court Another extracted example is Erlotinib → BAC, Drug Administration, EGFR, FDA, Food, Genzyme, In, Overall, Patients, PFS, The. Use these groups to spot repeated connection types before inspecting the individual relationships.

Erlotinib

Top relations

related to Society and culture · 14
Erlotinib → Cipla, Delaware, Genentech, In India, In May, Indian, It, Mylan Pharmaceuticals, OSI Pharmaceutical LLC, OSI Pharmaceuticals, Roche, The, United States, US District Court
related to Lung cancer · 11
Erlotinib → BAC, Drug Administration, EGFR, FDA, Food, Genzyme, In, Overall, Patients, PFS, The
has treatment · 10
Erlotinib → Approximately, As, ATP, CML, EGFR, ERBB3, In, Over, PI3K, T790M
related to Interactions · 9
Erlotinib → Also, Compounds, CYP3A4, OATP-1B1, OATP-1B3, OATP1B1, OATP1B3, OATPs, St John's
related to Mechanism · 8
Erlotinib → ATP, EGFR, For, Iressa, It, The, These, When
Legal status · 3
Erlotinib → AU: S4 (Prescription only), UK: POM (Prescription only), US: ℞-only
related to Pancreatic cancer · 2
Erlotinib → FDA, In November
3D model (JSmol) · 1
Erlotinib → Interactive image
AHFS/Drugs.com · 1
Erlotinib → Monograph
ATC code · 1
Erlotinib → L01EB02 (WHO)

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

egfr cancer lung receptor epidermal growth factor effects patients may use side drug tyrosine kinase rash liver resistance treatment pancreatic

Erlotinib relationships Subject–Predicate–Object triples

TTTA extracted 85 structured relationships around Erlotinib. Examples in this analysis include Erlotinib → 3D model (JSmol) → Interactive image and Erlotinib → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Erlotinib3D model (JSmol)Interactive image1.00infobox
ErlotinibAHFS/Drugs.comMonograph1.00infobox
ErlotinibATC codeL01EB02 (WHO)1.00infobox
ErlotinibBioavailability59%1.00infobox
ErlotinibCAS Number183321-74-6 Y1.00infobox
ErlotinibChEBICHEBI:114785 Y1.00infobox
ErlotinibChEMBLChEMBL553 Y1.00infobox
ErlotinibChemSpider154044 Y1.00infobox
ErlotinibCompTox Dashboard (EPA)DTXSID80464541.00infobox
ErlotinibDrugBankDB00530 Y1.00infobox
ErlotinibECHA InfoCard100.216.0201.00infobox
ErlotinibElimination half-life36.2 hrs (median)1.00infobox
ErlotinibExcretion>98% as metabolites, of which >90% via feces, 9% via urine1.00infobox
ErlotinibFormulaC22H23N3O41.00infobox
ErlotinibIUPHAR/BPS49201.00infobox
ErlotinibKEGGD07907 Y1.00infobox
ErlotinibLegal statusAU: S4 (Prescription only)1.00infobox
ErlotinibLegal statusUK: POM (Prescription only)1.00infobox
ErlotinibLegal statusUS: ℞-only1.00infobox
ErlotinibLicense dataUS DailyMed: Erlotinib1.00infobox
ErlotinibMedlinePlusa6050081.00infobox
ErlotinibMetabolismLiver (mainly CYP3A4, less CYP1A2)1.00infobox
ErlotinibMolar mass393.443 g·mol−11.00infobox
ErlotinibOther namesErlotinib hydrochloride1.00infobox
ErlotinibPregnancy categoryAU: C1.00infobox
ErlotinibProtein binding95%1.00infobox
ErlotinibPubChem CID1768701.00infobox
ErlotinibRoutes of administrationBy mouth1.00infobox
ErlotinibTrade namesTarceva1.00infobox
ErlotinibUNIIJ4T82NDH7E1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Erlotinib bring nearby vocabulary together. In this analysis, examples include Cancer, Lung and Treatment. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Erlotinib
    • Cancer
    • Lung
    • Treatment
    • Approved
    • Cell
    • Non-small
    • Pancreatic
    • Egfr
    • Epidermal
    • Medical
    • Name
    • Tarceva
  • erlotinib
    • Cancer
    • Lung
    • Treatment
    • Approved
    • Cell
    • Non-small
    • Pancreatic
    • Egfr
    • Epidermal
    • Medical
    • Name
    • Tarceva
  • non-small cell lung cancer
    • Non-small
    • Name
    • Tarceva
    • Chemotherapy
    • Lung
    • Pancreatic
    • Treatment
    • Cancer
    • Cell
    • Effects
    • Erlotinib
    • Patients
  • pancreatic cancer
    • Tarceva
    • Lung
    • Treatment
    • Cell
    • Non-small
    • Pancreatic
    • Erlotinib
    • Common
    • Medical
    • Name
    • Pregnancy
    • Used
  • interstitial lung disease
    • Non-small
    • Effects
    • Patients
    • Name
    • Tarceva
    • Chemotherapy
    • Liver
    • Pancreatic
    • Side
    • May
    • Survival
    • Treatment
  • side effects
    • Side
    • Diarrhea
    • Include
    • Liver
    • Rash
    • Lung
    • Survival
    • Tarceva
    • Medical
    • Name
    • Pregnancy
    • Binding
  • epidermal growth factor receptor
    • Factor
    • Growth
    • Receptor
    • Egfr
    • Inhibitor
    • Kinase
    • Tyrosine
    • Erlotinib
    • Nsclc
    • Used
    • Mutation
    • Mutations
  • egfr inhibitor
    • Epidermal
    • Factor
    • Growth
    • Receptor
    • Mutation
    • Mutations
    • Kinase
    • Tyrosine
    • Erlotinib
    • Inhibitor
    • Atp
    • Patients

Connections between topic areas Semantic bridges

For Erlotinib, one of the stronger structural bridges in this analysis connects Erlotinib with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Erlotinib — Overview · splits 46 ⟂ 15
Erlotinib — Side effects · splits 46 ⟂ 15
Erlotinib — Medical uses · splits 47 ⟂ 14
Erlotinib — Mechanism · splits 54 ⟂ 7
Erlotinib — Society and culture · splits 56 ⟂ 5
Erlotinib — Interactions · splits 57 ⟂ 4

Map overview Semantic statistics

Erlotinib

Nodes61
Edges60
Triples85
Avg. degree1.97
Density0.032787
Components1

Source & methodology

TTTA analyzes the structure around Erlotinib to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Community, Culture, Applications & Art, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Erlotinib · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.