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Gastrin

Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas.

[EN, English, English]

History, Physiology & Overview

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Explore the main themes, entities and connections around Gastrin. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GAST, GAS, gastrin
Band
17q21.2 · 11 D|11 63.46 cM
Bgee
pylorus · duodenum · pancreatic ductal cell · islet of Langerhans · placenta
BioGPS
n/a
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)
Databases
NCBI: entry; OMA: entry

Topics to explore

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Overview

Physiology

Role in disease

History

Advanced semantic analysis

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Map overview Semantic statistics

Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.

Gastrin

Nodes76
Edges75
Triples98
Avg. degree1.97
Density0.026316
Components1

How this topic connects Entity context

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Gastrin

Top relations

Bgee · 20
Gastrin → CA3 field, choroid plexus of fourth ventricle, cingulate gyrus, duodenum, embryo, endometrium, entorhinal cortex, epithelium of stomach, hypothalamus, islet of Langerhans, metanephros, morula, mucosa of nose, mucous cell of stomach, pancreatic ductal cell, perirhinal cortex, placenta, pyloric antrum, pylorus, upper respiratory tract
RNA expression pattern · 20
Gastrin → CA3 field, choroid plexus of fourth ventricle, cingulate gyrus, duodenum, embryo, endometrium, entorhinal cortex, epithelium of stomach, hypothalamus, islet of Langerhans, metanephros, morula, mucosa of nose, mucous cell of stomach, pancreatic ductal cell, perirhinal cortex, placenta, pyloric antrum, pylorus, upper respiratory tract
related to Role in disease · 9
Gastrin → Additionally, Ellison, Eventually, In, IV, Plasma, This, To, Zollinger
Gene ontology · 8
Gastrin → extracellular region, extracellular space, G protein-coupled receptor signaling pathway, hormone activity, protein binding, regulation of signaling receptor activity, response to food, signal transduction
related to history · 8
Gastrin → British, Hilda Tracy, In, Its, John Sydney Edkins, Liverpool, Roderic Alfred Gregory, University
related to Function · 6
Gastrin → Along, CCK2/gastrin, ECL, HCl, The, This
related to Release · 3
Gastrin → Aromatic, GRP, These
Band · 2
Gastrin → 11 D|11 63.46 cM, 17q21.2
Chr. · 2
Gastrin → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
Gastrin → 100,227,822 bp, 41,715,969 bp

Important terminology Word statistics

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Important terminology

stomach cells acid parietal release bp secretion human chr band chromosome duodenum peptide gastric 17 pyloric antrum gene somatostatin amino

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
GastrinAliasesGAST, GAS, gastrin1.00infobox
GastrinBand17q21.21.00infobox
GastrinBand11 D|11 63.46 cM1.00infobox
GastrinBgeepylorus1.00infobox
GastrinBgeeduodenum1.00infobox
GastrinBgeepancreatic ductal cell1.00infobox
GastrinBgeeislet of Langerhans1.00infobox
GastrinBgeeplacenta1.00infobox
GastrinBgeemetanephros1.00infobox
GastrinBgeehypothalamus1.00infobox
GastrinBgeeupper respiratory tract1.00infobox
GastrinBgeeendometrium1.00infobox
GastrinBgeemucosa of nose1.00infobox
GastrinBgeepyloric antrum1.00infobox
GastrinBgeeepithelium of stomach1.00infobox
GastrinBgeemorula1.00infobox
GastrinBgeemucous cell of stomach1.00infobox
GastrinBgeeCA3 field1.00infobox
GastrinBgeecingulate gyrus1.00infobox
GastrinBgeechoroid plexus of fourth ventricle1.00infobox
GastrinBgeeembryo1.00infobox
GastrinBgeeentorhinal cortex1.00infobox
GastrinBgeeperirhinal cortex1.00infobox
GastrinBioGPSn/a1.00infobox
GastrinChr.Chromosome 17 (human)1.00infobox
GastrinChr.Chromosome 11 (mouse)1.00infobox
GastrinDatabasesNCBI: entry; OMA: entry1.00infobox
GastrinEnd41,715,969 bp1.00infobox
GastrinEnd100,227,822 bp1.00infobox
GastrinEnsemblENSG000001845021.00infobox

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