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Clostridioides difficile

Clostridioides difficile (syn. Clostridium difficile) is a bacterium known for causing serious diarrheal infections, and may also cause colon cancer. It is known also as C. difficile, or C. diff (/siː dɪf/), and is a Gram-positive species of spore-forming bacteria. Clostridioides spp. are anaerobic, motile bacteria, ubiquitous in nature and especially…

Human pathogen, Possible role in colon cancer & Overview

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Overview

Taxonomy

Human pathogen

Antibiotic resistance

Transmission

Signs and symptoms

Pathophysiology

Immune response

Possible role in colon cancer

Diagnosis

Treatment

Strains

Genome

Bacteriophage

Advanced semantic analysis

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Map overview Semantic statistics

Clostridioides difficile

Nodes121
Edges120
Triples80
Avg. degree1.98
Density0.016529
Components1

How this topic connects Entity context

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Clostridioides difficile

Top relations

related to Transmission · 15
Clostridioides difficile → Any, Because, CamA, Clostridioides, Consequently, Crohn's, DNA, GI, Once, Spores, Sporulation, Susceptibility, The, They, World Health Organization
related to Pathophysiology · 11
Clostridioides difficile → Additionally, Clostridioides, CspC, CWp84, GMP, Secondary, Spore, Spores, The, These, US
has prevention · 9
Clostridioides difficile → Additionally, Alcohol-based, Also, Another, Appropriate, CDI, CDIs, Clostridioides, Furthermore
related to Antibiotic resistance · 9
Clostridioides difficile → Antibiotic, Atlanta, CDI, Clostridioides, Disease Control, In, North America, US Centers, While
related to Persistence in the gut · 8
Clostridioides difficile → Beyond, Cell-surface, Clostridioides, CWPs, S-layer, The S-layer, These, Unlike
related to Research · 6
Clostridioides difficile → Clostridioides, Deletion, However, S-layer, The, Triton X-100
related to Taxonomy · 5
Clostridioides difficile → As, Clostridioides, Clostridium, The, This
related to Host range · 4
Clostridioides difficile → Americans, CDC, Clostridioides, The
related to Epigenome · 3
Clostridioides difficile → CAAAAA, Clostridioides, Methylation
is a · 1
Clostridioides difficile → important human pathogen

Important terminology Word statistics

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Important terminology

difficile clostridioides spores infection may patients cells antibiotic also toxins colon human vancomycin toxin cdi antibiotics treatment strain infections clostridium

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Clostridioides difficileis aimportant human pathogen0.90text
prolineinstance ofCodY is a global nutrient-sensing repressor that suppresses toxin gene expression when preferred amino acids0.80text
glycineinstance ofCodY is a global nutrient-sensing repressor that suppresses toxin gene expression when preferred amino acids0.80text
leucineinstance ofCodY is a global nutrient-sensing repressor that suppresses toxin gene expression when preferred amino acids0.80text
and valine are abundantinstance ofCodY is a global nutrient-sensing repressor that suppresses toxin gene expression when preferred amino acids0.80text
metronidazoleinstance ofresistance to other antibiotics0.80text
the first choice of antimicrobial drug when treating CDIinstance ofresistance to other antibiotics0.80text
was observed in up to 12instance ofresistance to other antibiotics0.80text
chronic inflammationinstance ofPossible role in colon cancerStudies indicate that C. difficile infection may contribute to colorectal cancer development through mechanisms0.80text
epithelial barrier disruptioninstance ofPossible role in colon cancerStudies indicate that C. difficile infection may contribute to colorectal cancer development through mechanisms0.80text
Clostridioides difficilehas preventionAppropriate0.60section
Clostridioides difficilehas preventionAdditionally0.60section

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    Min side: 3
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