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NLR family CARD domain-containing protein 4 is a protein that in humans is encoded by the NLRC4 gene.
The analysis highlights Function, Structure and Clinical significance as prominent areas in the source structure around NLRC4.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around NLRC4 shows recurring relationship patterns in the source. For example, NLRC4 → activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of innate immune response, apoptotic process, ATP binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, cytoplasm, cytosol, defense response to bacterium, detection of bacterium, identical protein binding, immune system process, inflammatory response, inhibition of cysteine-type endopeptidase activity involved in apoptotic process, innate immune response, intracellular anatomical structure, IPAF inflammasome complex, magnesium ion binding, mitotic spindle assembly, nucleotide binding, nucleus Another extracted example is NLRC4 → appendix, blood, bone marrow, bone marrow cell, colon, duodenum, gonad, granulocyte, ileum, jejunum, monocyte, primary oocyte, proximal tubule, secondary oocyte, spleen, stomach, testicle, trabecular bone, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
human bp inflammasome family chr band protein gene card chromosome nlrp3 nlr location structure mouse domain function ced4 proteins associated
TTTA extracted 134 structured relationships around NLRC4. Examples in this analysis include NLRC4 → Aliases → NLRC4, CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, IPAF, AIFEC, FCAS4, NLR family, CARD domain containing 4, NLR family CARD domain containing 4 and NLRC4 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4KXF. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| NLRC4 | Aliases | NLRC4, CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, IPAF, AIFEC, FCAS4, NLR family, CARD domain containing 4, NLR family CARD domain containing 4 | 1.00 | infobox |
| NLRC4 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4KXF | 1.00 | infobox |
| NLRC4 | Band | 2p22.3 | 1.00 | infobox |
| NLRC4 | Band | 17|17 E2 | 1.00 | infobox |
| NLRC4 | Bgee | monocyte | 1.00 | infobox |
| NLRC4 | Bgee | blood | 1.00 | infobox |
| NLRC4 | Bgee | granulocyte | 1.00 | infobox |
| NLRC4 | Bgee | gonad | 1.00 | infobox |
| NLRC4 | Bgee | trabecular bone | 1.00 | infobox |
| NLRC4 | Bgee | testicle | 1.00 | infobox |
| NLRC4 | Bgee | bone marrow | 1.00 | infobox |
| NLRC4 | Bgee | bone marrow cell | 1.00 | infobox |
| NLRC4 | Bgee | spleen | 1.00 | infobox |
| NLRC4 | Bgee | appendix | 1.00 | infobox |
| NLRC4 | Bgee | jejunum | 1.00 | infobox |
| NLRC4 | Bgee | ileum | 1.00 | infobox |
| NLRC4 | Bgee | zygote | 1.00 | infobox |
| NLRC4 | Bgee | duodenum | 1.00 | infobox |
| NLRC4 | Bgee | colon | 1.00 | infobox |
| NLRC4 | Bgee | secondary oocyte | 1.00 | infobox |
| NLRC4 | Bgee | primary oocyte | 1.00 | infobox |
| NLRC4 | Bgee | proximal tubule | 1.00 | infobox |
| NLRC4 | Bgee | stomach | 1.00 | infobox |
| NLRC4 | BioGPS | n/a | 1.00 | infobox |
| NLRC4 | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| NLRC4 | Chr. | Chromosome 17 (mouse) | 1.00 | infobox |
| NLRC4 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| NLRC4 | End | 32,265,732 bp | 1.00 | infobox |
| NLRC4 | End | 74,766,137 bp | 1.00 | infobox |
| NLRC4 | Ensembl | ENSG00000091106 | 1.00 | infobox |
The concept neighborhoods around NLRC4 bring nearby vocabulary together. In this analysis, examples include Inflammasome, May and Structure. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For NLRC4, one of the stronger structural bridges in this analysis connects NLRC4 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around NLRC4 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Structure & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — NLRC4 · EN edition · Analysis: TopicsToTalkAbout