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DFNA5: Function & Overview

Non-syndromic hearing impairment protein 5 is a protein that in humans is encoded by the DFNA5 gene.

Language: English [EN]
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DFNA5 topic overview

The analysis highlights Function and Overview as prominent areas in the source structure around DFNA5.

Related topics
6
Source areas
2
Connected nodes
8
Extracted relationships
83
Related term clusters
6
Bridge connections
8

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 4 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GSDME, ICERE-1, DFNA5, DFNA5, deafness associated tumor suppressor, gasdermin E
Band
7p15.3 · 6|6 B2.3
Bgee
germinal epithelium · jejunal mucosa · stromal cell of endometrium · endothelial cell · optic nerve
BioGPS
More reference expression data
Chr.
Chromosome 7 (human) · Chromosome 6 (mouse)
Databases
NCBI: entry; OMA: entry

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Explore all related topics Closing gaps

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Overview

Function

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How DFNA5 connects Entity context

The extracted context around DFNA5 shows recurring relationship patterns in the source. For example, DFNA5 → decidua, endothelial cell, germinal epithelium, granulocyte, habenula, jejunal mucosa, lateral geniculate nucleus, mammillary body, medial ganglionic eminence, middle temporal gyrus, oocyte, optic nerve, pineal gland, placenta, secondary oocyte, sternocleidomastoid muscle, stromal cell of endometrium, temporal muscle, triceps brachii muscle, vastus lateralis muscle Another extracted example is DFNA5 → cardiolipin binding, cell death, cellular response to tumor necrosis factor, cellular response to virus, cytoplasm, cytosol, hearing, inner ear receptor cell differentiation, membrane, necrotic cell death, negative regulation of cell population proliferation, phosphatidylinositol-4,5-bisphosphate binding, plasma membrane, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of MAPK cascade, programmed cell death, pyroptosis. Use these groups to spot repeated connection types before inspecting the individual relationships.

DFNA5

Top relations

Bgee · 20
DFNA5 → decidua, endothelial cell, germinal epithelium, granulocyte, habenula, jejunal mucosa, lateral geniculate nucleus, mammillary body, medial ganglionic eminence, middle temporal gyrus, oocyte, optic nerve, pineal gland, placenta, secondary oocyte, sternocleidomastoid muscle, stromal cell of endometrium, temporal muscle, triceps brachii muscle, vastus lateralis muscle
RNA expression pattern · 20
DFNA5 → decidua, endothelial cell, germinal epithelium, granulocyte, habenula, jejunal mucosa, lateral geniculate nucleus, mammillary body, medial ganglionic eminence, middle temporal gyrus, oocyte, optic nerve, pineal gland, placenta, secondary oocyte, sternocleidomastoid muscle, stromal cell of endometrium, temporal muscle, triceps brachii muscle, vastus lateralis muscle
Gene ontology · 17
DFNA5 → cardiolipin binding, cell death, cellular response to tumor necrosis factor, cellular response to virus, cytoplasm, cytosol, hearing, inner ear receptor cell differentiation, membrane, necrotic cell death, negative regulation of cell population proliferation, phosphatidylinositol-4,5-bisphosphate binding, plasma membrane, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of MAPK cascade, programmed cell death, pyroptosis
related to Function · 5
DFNA5 → Hearing, Indeed, Moreover, Nonsyndromic, P53
Band · 2
DFNA5 → 6|6 B2.3, 7p15.3
Chr. · 2
DFNA5 → Chromosome 6 (mouse), Chromosome 7 (human)
End · 2
DFNA5 → 24,757,940 bp, 50,240,842 bp
Aliases · 1
DFNA5 → GSDME, ICERE-1, DFNA5, DFNA5, deafness associated tumor suppressor, gasdermin E
BioGPS · 1
DFNA5 → More reference expression data
Databases · 1
DFNA5 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp chr human band hearing chromosome tumor protein location function impairment gsdme mouse external encoded 757 940 end 24

DFNA5 relationships Subject–Predicate–Object triples

TTTA extracted 83 structured relationships around DFNA5. Examples in this analysis include DFNA5 → Aliases → GSDME, ICERE-1, DFNA5, DFNA5, deafness associated tumor suppressor, gasdermin E and DFNA5 → Band → 7p15.3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
DFNA5AliasesGSDME, ICERE-1, DFNA5, DFNA5, deafness associated tumor suppressor, gasdermin E1.00infobox
DFNA5Band7p15.31.00infobox
DFNA5Band6|6 B2.31.00infobox
DFNA5Bgeegerminal epithelium1.00infobox
DFNA5Bgeejejunal mucosa1.00infobox
DFNA5Bgeestromal cell of endometrium1.00infobox
DFNA5Bgeeendothelial cell1.00infobox
DFNA5Bgeeoptic nerve1.00infobox
DFNA5Bgeeplacenta1.00infobox
DFNA5Bgeeoocyte1.00infobox
DFNA5Bgeesecondary oocyte1.00infobox
DFNA5Bgeemiddle temporal gyrus1.00infobox
DFNA5Bgeedecidua1.00infobox
DFNA5Bgeepineal gland1.00infobox
DFNA5Bgeemammillary body1.00infobox
DFNA5Bgeetemporal muscle1.00infobox
DFNA5Bgeemedial ganglionic eminence1.00infobox
DFNA5Bgeetriceps brachii muscle1.00infobox
DFNA5Bgeesternocleidomastoid muscle1.00infobox
DFNA5Bgeegranulocyte1.00infobox
DFNA5Bgeevastus lateralis muscle1.00infobox
DFNA5Bgeelateral geniculate nucleus1.00infobox
DFNA5Bgeehabenula1.00infobox
DFNA5BioGPSMore reference expression data1.00infobox
DFNA5Chr.Chromosome 7 (human)1.00infobox
DFNA5Chr.Chromosome 6 (mouse)1.00infobox
DFNA5DatabasesNCBI: entry; OMA: entry1.00infobox
DFNA5End24,757,940 bp1.00infobox
DFNA5End50,240,842 bp1.00infobox
DFNA5EnsemblENSG000001059281.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around DFNA5 bring nearby vocabulary together. In this analysis, examples include Tumor, Gene and Suppressor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • DFNA5
    • Tumor
    • Gene
    • Suppressor
    • External
    • Humans
    • Links
    • Non-syndromic
    • Reading
    • References
    • Associated
    • Cellular
    • Deafness
  • dfna5
    • Tumor
    • Gene
    • Suppressor
    • External
    • Humans
    • Links
    • Non-syndromic
    • Reading
    • References
    • Associated
    • Cellular
    • Deafness
  • gene
    • Tumor
    • Function
    • Impairment
    • Location
    • Protein
    • Chromosome
    • Hearing
    • Human
    • Bp
    • Chr
    • Associated
    • B2
  • nonsyndromic hearing impairment
    • Impairment
    • Entry
    • Ncbi
    • Protein
    • Gene
    • Humans
    • Non-syndromic
    • Associated
    • B2
    • Cellular
    • Encoded
    • End
  • function
    • Expressed
    • Gsdme
    • Location
    • Protein
    • Chromosome
    • Human
    • Tumor
    • Gene
    • Bp
    • Chr
    • External
    • Links
  • protein
    • Ncbi
    • Tumor

Connections between topic areas Semantic bridges

For DFNA5, one of the stronger structural bridges in this analysis connects DFNA5 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
DFNA5 — Function · splits 4 ⟂ 5
DFNA5 — Overview · splits 6 ⟂ 3

Map overview Semantic statistics

DFNA5

Nodes9
Edges8
Triples83
Avg. degree1.78
Density0.222222
Components1

Source & methodology

TTTA analyzes the structure around DFNA5 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — DFNA5 · EN edition · Analysis: TopicsToTalkAbout

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