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Nitrile: History & Applications

In organic chemistry, a nitrile is any organic compound that has a −C≡N functional group. The name of the compound is composed of a base, which includes the carbon of the −C≡N, suffixed with "nitrile", so for example CH3CH2C≡N is called "propionitrile" (or propanenitrile). The prefix cyano- is used interchangeably with the term nitrile in industrial…

Language: English [EN]
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Nitrile topic overview

The analysis highlights History and Applications as prominent areas in the source structure around Nitrile.

Related topics
604
Source areas
9
Connected nodes
613
Extracted relationships
362
Concept neighborhoods
115
Bridge connections
613

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Synthesis · 191 topics
Use · 134 topics
Occurrence · 106 topics
Overview · 81 topics
Reactions · 39 topics
History · 24 topics
Nitrile derivatives · 24 topics
Nomenclature · 3 topics
Structure and basic properties · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure and basic properties

History

Nomenclature

Synthesis

Reactions

Nitrile derivatives

Occurrence

Use

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Nitrile connects Entity context

The extracted context around Nitrile shows recurring relationship patterns in the source. For example, Nitrile → Alcohols, Alternative, Amino, Antoine Paul Nicolas Franchimont, Aromatic, Aryl, Belgian, Braun, Carbocyanation, Carboxylic, CCl3, Decyanations, Et2AlCN, For, Franchimont Reaction, From, HCN, Henry Drysdale Dakin, HMPA, Houben-Fischer Another extracted example is Nitrile → Abraxas, Arthropoda, Chilopoda, Coleoptera, Diplopoda, Gooseberry, Hemiptera, Himantarium, Hydrogen, In, Jadera, Lepidoptera, Marsh Hornwort, Numerous, Oribatida, Oribatula, Other, Parnassius, Phenylacetonitrile, Polydesmida. Use these groups to spot repeated connection types before inspecting the individual relationships.

Nitrile

Top relations

has method · 38
Nitrile → Alcohols, Alternative, Amino, Antoine Paul Nicolas Franchimont, Aromatic, Aryl, Belgian, Braun, Carbocyanation, Carboxylic, CCl3, Decyanations, Et2AlCN, For, Franchimont Reaction, From, HCN, Henry Drysdale Dakin, HMPA, Houben-Fischer
related to Occurrence in animals · 26
Nitrile → Abraxas, Arthropoda, Chilopoda, Coleoptera, Diplopoda, Gooseberry, Hemiptera, Himantarium, Hydrogen, In, Jadera, Lepidoptera, Marsh Hornwort, Numerous, Oribatida, Oribatula, Other, Parnassius, Phenylacetonitrile, Polydesmida
related to Occurrence in plants · 20
Nitrile → Acacia, Acacipetalin, Cyanolipids, European, Heracleum, Hydrogen, Ilex, In, In Ricinus, Lathyrus, N-glutamyl-3-aminopropionitrile, Numerous, Ricinus, Sapindaceae, Soap, Sutherlandin, The, Their, Trevia, Unsaturated
related to Nitriles in medicine · 15
Nitrile → As, Between, Drug Administration, For, In, Incorporation, It, Nitriles, PDE-3, Structurally, The, These, This, US Food, Verapamil
related to Preparation of aromatic nitriles · 13
Nitrile → Another, Aryl, Conversion, For, Grignard, II, Letts, Palladium-catalyzed, Pd, PPh3, Quinones, Rosenmund-von Braun, Sandmeyer
related to history · 12
Nitrile → Around, Fehling, Friedrich Wöhler, Gay-Lussac, He, Hermann Fehling, In, Justus, Liebig, Scheele, The, Théophile-Jules Pelouze
related to Occurrence in fungi · 12
Nitrile → Clitocybe, Diatretin II, Emericella, Fleshy Fungus, In, Many, Marasmius, Polyporus, Ritterlinge, The, These, Tricholoma
related to Plastics production · 12
Nitrile → Acrylic, Acrylonitrile, Another, Copolymers, Global, In, PAN, Pure, Several, Such, These, They
related to Dehydration of amides and others · 10
Nitrile → Braun, C-N, Common, In, Methods, Nitriles, Numerous, P2O5, SOCl2, Specifically
related to Occurrence in bacteria · 10
Nitrile → Aeromonas, Aetokthonos, Bacillus, Biosynthesis, From Micromonospora, Hydrogen, It, Pseudomonas, Streptomyces, The

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cyanide nitriles also acid hydrogen group used compounds reaction synthesis addition example carbon acrylonitrile acetonitrile important organic cyanides several atom

Nitrile relationships Subject–Predicate–Object triples

TTTA extracted 362 structured relationships around Nitrile. Examples in this analysis include Nitrile → is a → highest-ranking functional group and acetone cyanohydrin or isovaleronitrile may be used → instance of → as synthetic equivalents. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Nitrileis ahighest-ranking functional group0.90text
acetone cyanohydrin or isovaleronitrile may be usedinstance ofas synthetic equivalents0.80text
phosphorus trichloride or triphenyl phosphiteinstance ofAmides can also be dehydrated using trivalent phosphorus reagents0.80text
aliphatic aldoxime dehydratase are also effective.Aldoximes may also be dehydrated with cyanuric chlorideinstance ofBiocatalysts0.80text
the Burgess reagentinstance ofBiocatalysts0.80text
or a combination of trifluoromethanesulfonic acid anhydrideinstance ofBiocatalysts0.80text
triphenylphosphineinstance ofBiocatalysts0.80text
the latter being oxidized to triphenylphosphine oxideinstance ofBiocatalysts0.80text
TEMPO or 4-acetamido-TEMPO as catalytic oxidantsinstance ofseveral selective methods have been developed in the last decades for electrochemical processes.Several procedures employ nitroxyl radicals0.80text
lanthanuminstance ofSuitable catalysts for this transformation include lanthanide alkoxides0.80text
trimethylaluminum or triphenylboraneinstance offor example by employing a different phosphane or adding a frustrated Lewis pair0.80text
allows addition of non-aromatic nitrilesinstance offor example by employing a different phosphane or adding a frustrated Lewis pair0.80text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Nitrile bring nearby vocabulary together. In this analysis, examples include Group, Synthesis and Carbon. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Nitrile
    • Group
    • Synthesis
    • Carbon
    • Compounds
    • Used
    • Nitriles
    • Organic
    • Atom
    • Example
    • Cyanide
    • Acid
    • Compound
  • nitrile
    • Group
    • Synthesis
    • Carbon
    • Compounds
    • Used
    • Nitriles
    • Organic
    • Atom
    • Example
    • Cyanide
    • Acid
    • Compound
  • organic compound
    • Hydrocyanation
    • Nitrogen
    • Group
    • Organic
    • Acid
    • Atom
    • Carbon
    • Nitrile
    • Addition
    • Reaction
    • Hydrogen
    • Amides
  • functional group
    • Nitrile
    • Bond
    • Atom
    • Carbon
    • Compounds
    • Containing
    • Via
    • Nitriles
    • Addition
    • Hydrogen
    • Nitrogen
    • Used
  • nitrile rubber
    • Group
    • Synthesis
    • Carbon
    • Compounds
    • Used
    • Nitriles
    • Organic
    • Atom
    • Example
    • Cyanide
    • Acid
    • Compound
  • inorganic compounds
    • Organic
    • Containing
    • Atom
    • Nitrile
    • Hydrogen
    • Group
    • Nitriles
    • Form
    • Also
    • Bond
    • Cyanide
    • Hydrocyanation
  • gallic acid
    • Carboxylic
    • Cyanide
    • Compound
    • Using
    • Carbon
    • Nitrile
    • Synthesis
    • Also
    • Reaction
    • Amides
    • Nitriles
    • Hydrogen
  • formic acid
    • Carboxylic
    • Cyanide
    • Compound
    • Using
    • Carbon
    • Nitrile
    • Synthesis
    • Also
    • Reaction
    • Amides
    • Nitriles
    • Hydrogen

Connections between topic areas Semantic bridges

For Nitrile, one of the stronger structural bridges in this analysis connects Nitrile with Synthesis. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Nitrile — Synthesis · splits 422 ⟂ 192
Nitrile — Use · splits 479 ⟂ 135
Nitrile — Occurrence · splits 507 ⟂ 107
Nitrile — Overview · splits 532 ⟂ 82
Nitrile — Reactions · splits 574 ⟂ 40
Nitrile — History · splits 589 ⟂ 25
Nitrile — Nitrile derivatives · splits 589 ⟂ 25
Nitrile — Nomenclature · splits 610 ⟂ 4
Nitrile — Structure and basic properties · splits 611 ⟂ 3

Map overview Semantic statistics

Nitrile

Nodes614
Edges613
Triples362
Avg. degree2
Density0.003257
Components1

Source & methodology

TTTA analyzes the structure around Nitrile to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Nitrile · EN edition · Analysis: TopicsToTalkAbout

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