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Letrozole

Letrozole, sold under the brand name Femara among others, is an aromatase inhibitor medication that is used in the treatment of breast cancer for post-menopausal women.

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Explore the main themes, entities and connections around Letrozole. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
L02BG04 (WHO)
Bioavailability
99.9%
CAS Number
112809-51-5 Y
ChEBI
CHEBI:6413 Y

Topics to explore

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Overview

Medical uses

Contraindications

Side effects

Interactions

Pharmacology

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Letrozole

Nodes55
Edges54
Triples54
Avg. degree1.96
Density0.036364
Components1

How this topic connects Entity context

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Letrozole

Top relations

related to Ovulation induction · 6
Letrozole → Clomid, Compared, India, Indian, It, The
Legal status · 4
Letrozole → CA: Schedule VII, EU: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Breast cancer · 3
Letrozole → Drug Administration, FDA, United States Food
related to Interactions · 3
Letrozole → CYP2A6, CYP2A7, CYP2C19
related to Pharmacodynamics · 3
Letrozole → It, P450, The
related to Contraindications · 2
Letrozole → Breast, Precautions
related to Research · 2
Letrozole → It, The
related to Use in sports · 2
Letrozole → WADA, World Antidoping Agency
3D model (JSmol) · 1
Letrozole → Interactive image
AHFS/Drugs.com · 1
Letrozole → Monograph

Important terminology Word statistics

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Important terminology

aromatase breast women also used cancer use inhibitor tamoxifen post-menopausal shown treatment medication side effects medical drug antiestrogen estrogen effective

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Letrozole3D model (JSmol)Interactive image1.00infobox
LetrozoleAHFS/Drugs.comMonograph1.00infobox
LetrozoleATC codeL02BG04 (WHO)1.00infobox
LetrozoleBioavailability99.9%1.00infobox
LetrozoleCAS Number112809-51-5 Y1.00infobox
LetrozoleChEBICHEBI:6413 Y1.00infobox
LetrozoleChEMBLChEMBL1444 Y1.00infobox
LetrozoleChemSpider3765 Y1.00infobox
LetrozoleCompTox Dashboard (EPA)DTXSID40232021.00infobox
LetrozoleDrug classAromatase inhibitor; Antiestrogen1.00infobox
LetrozoleDrugBankDB01006 Y1.00infobox
LetrozoleECHA InfoCard100.200.3571.00infobox
LetrozoleElimination half-life2 days1.00infobox
LetrozoleExcretionKidney1.00infobox
LetrozoleFormulaC17H11N51.00infobox
LetrozoleIUPHAR/BPS52091.00infobox
LetrozoleKEGGD00964 Y1.00infobox
LetrozoleLegal statusCA: Schedule VII1.00infobox
LetrozoleLegal statusUK: POM (Prescription only)1.00infobox
LetrozoleLegal statusUS: ℞-only1.00infobox
LetrozoleLegal statusEU: Rx-only1.00infobox
LetrozoleLicense dataUS DailyMed: Letrozole1.00infobox
LetrozoleMedlinePlusa6980041.00infobox
LetrozoleMetabolismpharmacologically-inactive metabolites Bis(4-cyanophenyl)methanol and 4,4'-dicyanobenzophenone.1.00infobox
LetrozoleMolar mass285.310 g·mol−11.00infobox
LetrozoleProtein binding60%, mainly to albumin1.00infobox
LetrozolePubChem CID39021.00infobox
LetrozoleRoutes of administrationBy mouth1.00infobox
LetrozoleTrade namesFemara, others1.00infobox
LetrozoleUNII7LKK855W8I1.00infobox

Related concept clusters Concept neighborhoods

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    Connections between topic areas Semantic bridges

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