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Creatine (/ˈkriːətiːn/ or /ˈkriːətɪn/) is an organic compound that facilitates recycling of adenosine triphosphate (ATP) in vertebrates, primarily in their muscle and brain tissue. It is a popular dietary supplement.
History & Research
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muscle supplementation studies phosphocreatine found atp skeletal form brain effects also review performance function systematic safety use creatinine loading research
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| volume of distribution | instance of | Studies have not established pharmacokinetic parameters for clinical usage of creatine | 0.80 | text |
| clearance | instance of | Studies have not established pharmacokinetic parameters for clinical usage of creatine | 0.80 | text |
| bioavailability | instance of | Studies have not established pharmacokinetic parameters for clinical usage of creatine | 0.80 | text |
| mean residence time | instance of | Studies have not established pharmacokinetic parameters for clinical usage of creatine | 0.80 | text |
| absorption rate | instance of | Studies have not established pharmacokinetic parameters for clinical usage of creatine | 0.80 | text |
| and half life | instance of | Studies have not established pharmacokinetic parameters for clinical usage of creatine | 0.80 | text |
| intake amounts | instance of | A 2023 meta-analysis including 8 randomized controlled trials found that creatine supplementation improved memory performance with dosing parameters | 0.80 | text |
| duration having no additional effects | instance of | A 2023 meta-analysis including 8 randomized controlled trials found that creatine supplementation improved memory performance with dosing parameters | 0.80 | text |
| Creatine | related to Absorption | Endogenous | 0.60 | section |
| Creatine | related to Biosynthesis | It | 0.60 | section |
| Creatine | related to Biosynthesis | S-adenosyl | 0.60 | section |
| Creatine | related to Biosynthesis | In | 0.60 | section |
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