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NFKB1: Measurement, Interactions & Overview

Nuclear factor NF-kappa-B p105 subunit is a protein that in humans is encoded by the NFKB1 gene.

Language: English [EN]
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NFKB1 topic overview

The analysis highlights Measurement, Interactions and Overview as prominent areas in the source structure around NFKB1.

Related topics
27
Source areas
2
Connected nodes
29
Extracted relationships
160
Concept neighborhoods
7
Bridge connections
29

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 21 topics
Overview · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50, CVID12, nuclear factor kappa B subunit 1, NF-kappa-B1, NF-kB, NF-kappabeta
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MDI, 1MDJ, 1MDK, 1NFI, 1SVC, 2DBF, 2O61, 3GUT
Band
4q24 · 3 G3|3 62.82 cM
Bgee
cartilage tissue · Achilles tendon · monocyte · appendix · epithelium of colon
BioGPS
More reference expression data
Chr.
Chromosome 4 (human) · Chromosome 3 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How NFKB1 connects Entity context

The extracted context around NFKB1 shows recurring relationship patterns in the source. For example, NFKB1 → actinin binding, apoptotic process, cellular response to angiotensin, cellular response to dsRNA, cellular response to interleukin-1, cellular response to interleukin-6, cellular response to lipopolysaccharide, cellular response to mechanical stimulus, cellular response to nicotine, cellular response to tumor necrosis factor, chromatin binding, cytoplasm, cytosol, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, extracellular region, Fc-epsilon receptor signaling pathway Another extracted example is NFKB1 → Achilles tendon, appendix, blood, bone marrow cell, cartilage tissue, epithelium of colon, gallbladder, gastrula, granulocyte, Ileal epithelium, lactiferous gland, lip, lymph node, middle frontal gyrus, monocyte, otic vesicle, rectum, right lung, spleen, thymus. Use these groups to spot repeated connection types before inspecting the individual relationships.

NFKB1

Top relations

Gene ontology · 69
NFKB1 → actinin binding, apoptotic process, cellular response to angiotensin, cellular response to dsRNA, cellular response to interleukin-1, cellular response to interleukin-6, cellular response to lipopolysaccharide, cellular response to mechanical stimulus, cellular response to nicotine, cellular response to tumor necrosis factor, chromatin binding, cytoplasm, cytosol, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, extracellular region, Fc-epsilon receptor signaling pathway
Bgee · 20
NFKB1 → Achilles tendon, appendix, blood, bone marrow cell, cartilage tissue, epithelium of colon, gallbladder, gastrula, granulocyte, Ileal epithelium, lactiferous gland, lip, lymph node, middle frontal gyrus, monocyte, otic vesicle, rectum, right lung, spleen, thymus
RNA expression pattern · 20
NFKB1 → Achilles tendon, appendix, blood, bone marrow cell, cartilage tissue, epithelium of colon, gallbladder, gastrula, granulocyte, Ileal epithelium, lactiferous gland, lip, lymph node, middle frontal gyrus, monocyte, otic vesicle, rectum, right lung, spleen, thymus
related to Interactions · 18
NFKB1 → BCL3, C22orf25, HDAC1, HMGA2IKK2, ITGB3BP, IκBα, LYL1, MAP3K7IP2, MAP3K8, MEN1, NFKB2, NFKBIE, NOTCH1, Nuclear, RELA, RELB, STAT3, STAT6
related to External links · 6
NFKB1 → FactorBookNFKB This, Medicine, Medicine Medical Subject Headings, MeSH, National Library, United States National Library
Band · 2
NFKB1 → 3 G3|3 62.82 cM, 4q24
Chr. · 2
NFKB1 → Chromosome 3 (mouse), Chromosome 4 (human)
End · 2
NFKB1 → 102,617,302 bp, 135,397,308 bp
Aliases · 1
NFKB1 → NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50, CVID12, nuclear factor kappa B subunit 1, NF-kappa-B1, NF-kB, NF-kappabeta
Available structures · 1
NFKB1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MDI, 1MDJ, 1MDK, 1NFI, 1SVC, 2DBF, 2O61, 3GUT

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein nf-κb gene bp human chr band factor chromosome subunit transcription cell nf-kappab nuclear location 105 kd 50 activated various

NFKB1 relationships Subject–Predicate–Object triples

TTTA extracted 160 structured relationships around NFKB1. Examples in this analysis include NFKB1 → Aliases → NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50, CVID12, nuclear factor kappa B subunit 1, NF-kappa-B1, NF-kB, NF-kappabeta and NFKB1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MDI, 1MDJ, 1MDK, 1NFI, 1SVC, 2DBF, 2O61, 3GUT. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
NFKB1AliasesNFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50, CVID12, nuclear factor kappa B subunit 1, NF-kappa-B1, NF-kB, NF-kappabeta1.00infobox
NFKB1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MDI, 1MDJ, 1MDK, 1NFI, 1SVC, 2DBF, 2O61, 3GUT1.00infobox
NFKB1Band4q241.00infobox
NFKB1Band3 G3|3 62.82 cM1.00infobox
NFKB1Bgeecartilage tissue1.00infobox
NFKB1BgeeAchilles tendon1.00infobox
NFKB1Bgeemonocyte1.00infobox
NFKB1Bgeeappendix1.00infobox
NFKB1Bgeeepithelium of colon1.00infobox
NFKB1Bgeegallbladder1.00infobox
NFKB1Bgeebone marrow cell1.00infobox
NFKB1Bgeerectum1.00infobox
NFKB1Bgeemiddle frontal gyrus1.00infobox
NFKB1Bgeeblood1.00infobox
NFKB1Bgeegranulocyte1.00infobox
NFKB1Bgeespleen1.00infobox
NFKB1Bgeethymus1.00infobox
NFKB1Bgeelactiferous gland1.00infobox
NFKB1Bgeelymph node1.00infobox
NFKB1Bgeelip1.00infobox
NFKB1Bgeeotic vesicle1.00infobox
NFKB1BgeeIleal epithelium1.00infobox
NFKB1Bgeeright lung1.00infobox
NFKB1Bgeegastrula1.00infobox
NFKB1BioGPSMore reference expression data1.00infobox
NFKB1Chr.Chromosome 4 (human)1.00infobox
NFKB1Chr.Chromosome 3 (mouse)1.00infobox
NFKB1DatabasesNCBI: entry; OMA: entry1.00infobox
NFKB1End102,617,302 bp1.00infobox
NFKB1End135,397,308 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around NFKB1 bring nearby vocabulary together. In this analysis, examples include Nuclear, Gene and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • NFKB1
    • Nuclear
    • Gene
    • Human
    • P105
    • Protein
    • Search
    • Location
    • Nf-kappab
    • Subunit
    • Chromosome
    • Bp
    • Chr
  • nfkb1
    • Nuclear
    • Gene
    • Human
    • P105
    • Protein
    • Search
    • Location
    • Nf-kappab
    • Subunit
    • Chromosome
    • Bp
    • Chr
  • protein
    • Binding
    • Complex
    • Dna
    • Kd
    • Nf-kappab
    • Subunit
    • Transcription
    • Human
    • Biological
    • End
    • Expression
    • G3
  • gene
    • Location
    • Nuclear
    • Chromosome
    • Nfkb1
    • Bp
    • Chr
    • Human
    • Protein
    • End
    • G3
    • Mouse
    • Nf-kappa-b
  • transcription factor
    • Nuclear
    • Nfkb1
    • Gene
    • Nf-kappa-b
    • P105
    • Search
    • Location
    • Nf-kappab
    • Subunit
    • Transcription
    • Chromosome
    • Bp
  • nuclear receptor coactivator 1
    • Nfkb1
    • P105
    • Search
    • Gene
    • Location
    • Nf-kappab
    • Subunit
    • Chromosome
    • Bp
    • Chr
    • External
    • Human
  • nf-κb
    • Activated
    • Various
    • Cell
    • Transcription
    • Biological
    • Expression
    • Immune
    • Inflammatory
    • Nucleus
    • Specific
    • Subunit
    • Protein

Connections between topic areas Semantic bridges

For NFKB1, one of the stronger structural bridges in this analysis connects NFKB1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
NFKB1Interactions · splits 8 ⟂ 22
NFKB1Overview · splits 23 ⟂ 7

Map overview Semantic statistics

NFKB1

Nodes30
Edges29
Triples160
Avg. degree1.93
Density0.066667
Components1

Source & methodology

TTTA analyzes the structure around NFKB1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — NFKB1 · EN edition · Analysis: TopicsToTalkAbout

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