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MAP3K7IP2: Interactions & Overview

Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 is an enzyme that in humans is encoded by the MAP3K7IP2 gene.

Language: English [EN]
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MAP3K7IP2 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around MAP3K7IP2.

Related topics
22
Source areas
2
Connected nodes
24
Extracted relationships
92
Concept neighborhoods
10
Bridge connections
24

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 15 topics
Interactions · 7 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
TAB2, CHTD2, MAP3K7IP2, TAB-2, TGF-beta activated kinase 1/MAP3K7 binding protein 2, TGF-beta activated kinase 1 (MAP3K7) binding protein 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2DAE, 2WWZ, 2WX0, 2WX1
Band
6q25.1 · 10|10 A1
Bgee
parotid gland · ventricular zone · epithelium of colon · gastrocnemius muscle · cartilage tissue
BioGPS
More reference expression data
Chr.
Chromosome 6 (human) · Chromosome 10 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How MAP3K7IP2 connects Entity context

The extracted context around MAP3K7IP2 shows recurring relationship patterns in the source. For example, MAP3K7IP2 → cytoplasm, cytosol, development of the heart, endosome membrane, Fc-epsilon receptor signaling pathway, I-kappaB kinase/NF-kappaB signaling, interleukin-1-mediated signaling pathway, JNK cascade, K63-linked polyubiquitin modification-dependent protein binding, membrane, metal ion binding, MyD88-dependent toll-like receptor signaling pathway, negative regulation of autophagy, nucleoplasm, nucleotide-binding oligomerization domain containing signaling pathway, plasma membrane, positive regulation of I-kappaB kinase/NF-kappaB signaling, positive regulation of NF-kappaB transcription factor activity, positive regulation of protein kinase activity, protein binding Another extracted example is MAP3K7IP2 → abdominal wall, aortic valve, biceps brachii, cartilage tissue, epithelium of colon, extensor digitorum longus muscle, gastrocnemius muscle, genital tubercle, hair follicle, islet of Langerhans, left lung lobe, mesenteric lymph nodes, migratory enteric neural crest cell, monocyte, muscle layer of sigmoid colon, parotid gland, plantaris muscle, sciatic nerve, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

MAP3K7IP2

Top relations

Gene ontology · 23
MAP3K7IP2 → cytoplasm, cytosol, development of the heart, endosome membrane, Fc-epsilon receptor signaling pathway, I-kappaB kinase/NF-kappaB signaling, interleukin-1-mediated signaling pathway, JNK cascade, K63-linked polyubiquitin modification-dependent protein binding, membrane, metal ion binding, MyD88-dependent toll-like receptor signaling pathway, negative regulation of autophagy, nucleoplasm, nucleotide-binding oligomerization domain containing signaling pathway, plasma membrane, positive regulation of I-kappaB kinase/NF-kappaB signaling, positive regulation of NF-kappaB transcription factor activity, positive regulation of protein kinase activity, protein binding
Bgee · 19
MAP3K7IP2 → abdominal wall, aortic valve, biceps brachii, cartilage tissue, epithelium of colon, extensor digitorum longus muscle, gastrocnemius muscle, genital tubercle, hair follicle, islet of Langerhans, left lung lobe, mesenteric lymph nodes, migratory enteric neural crest cell, monocyte, muscle layer of sigmoid colon, parotid gland, plantaris muscle, sciatic nerve, ventricular zone
RNA expression pattern · 19
MAP3K7IP2 → abdominal wall, aortic valve, biceps brachii, cartilage tissue, epithelium of colon, extensor digitorum longus muscle, gastrocnemius muscle, genital tubercle, hair follicle, islet of Langerhans, left lung lobe, mesenteric lymph nodes, migratory enteric neural crest cell, monocyte, muscle layer of sigmoid colon, parotid gland, plantaris muscle, sciatic nerve, ventricular zone
related to Interactions · 8
MAP3K7IP2 → HDAC3, MAP3K7, MAP3K7IP3, NFKB1, Nuclear, NUMBL, TAB1, TRAF2
Band · 2
MAP3K7IP2 → 10|10 A1, 6q25.1
Chr. · 2
MAP3K7IP2 → Chromosome 10 (mouse), Chromosome 6 (human)
End · 2
MAP3K7IP2 → 149,411,613 bp, 7,956,230 bp
Aliases · 1
MAP3K7IP2 → TAB2, CHTD2, MAP3K7IP2, TAB-2, TGF-beta activated kinase 1/MAP3K7 binding protein 2, TGF-beta activated kinase 1 (MAP3K7) binding protein 2
Available structures · 1
MAP3K7IP2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2DAE, 2WWZ, 2WX0, 2WX1
BioGPS · 1
MAP3K7IP2 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein human map3k7 gene kinase bp chr band chromosome tab1 mouse receptor location pdb uniprot encoded activator induced activation jnk

MAP3K7IP2 relationships Subject–Predicate–Object triples

TTTA extracted 92 structured relationships around MAP3K7IP2. Examples in this analysis include MAP3K7IP2 → Aliases → TAB2, CHTD2, MAP3K7IP2, TAB-2, TGF-beta activated kinase 1/MAP3K7 binding protein 2, TGF-beta activated kinase 1 (MAP3K7) binding protein 2 and MAP3K7IP2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2DAE, 2WWZ, 2WX0, 2WX1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
MAP3K7IP2AliasesTAB2, CHTD2, MAP3K7IP2, TAB-2, TGF-beta activated kinase 1/MAP3K7 binding protein 2, TGF-beta activated kinase 1 (MAP3K7) binding protein 21.00infobox
MAP3K7IP2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2DAE, 2WWZ, 2WX0, 2WX11.00infobox
MAP3K7IP2Band6q25.11.00infobox
MAP3K7IP2Band10|10 A11.00infobox
MAP3K7IP2Bgeeparotid gland1.00infobox
MAP3K7IP2Bgeeventricular zone1.00infobox
MAP3K7IP2Bgeeepithelium of colon1.00infobox
MAP3K7IP2Bgeegastrocnemius muscle1.00infobox
MAP3K7IP2Bgeecartilage tissue1.00infobox
MAP3K7IP2Bgeehair follicle1.00infobox
MAP3K7IP2Bgeeislet of Langerhans1.00infobox
MAP3K7IP2Bgeemonocyte1.00infobox
MAP3K7IP2Bgeemuscle layer of sigmoid colon1.00infobox
MAP3K7IP2Bgeebiceps brachii1.00infobox
MAP3K7IP2Bgeeplantaris muscle1.00infobox
MAP3K7IP2Bgeeextensor digitorum longus muscle1.00infobox
MAP3K7IP2Bgeegenital tubercle1.00infobox
MAP3K7IP2Bgeeleft lung lobe1.00infobox
MAP3K7IP2Bgeesciatic nerve1.00infobox
MAP3K7IP2Bgeeaortic valve1.00infobox
MAP3K7IP2Bgeeabdominal wall1.00infobox
MAP3K7IP2Bgeemesenteric lymph nodes1.00infobox
MAP3K7IP2Bgeemigratory enteric neural crest cell1.00infobox
MAP3K7IP2BioGPSMore reference expression data1.00infobox
MAP3K7IP2Chr.Chromosome 6 (human)1.00infobox
MAP3K7IP2Chr.Chromosome 10 (mouse)1.00infobox
MAP3K7IP2DatabasesNCBI: entry; OMA: entry1.00infobox
MAP3K7IP2End149,411,613 bp1.00infobox
MAP3K7IP2End7,956,230 bp1.00infobox
MAP3K7IP2EnsemblENSG000000552081.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around MAP3K7IP2 bring nearby vocabulary together. In this analysis, examples include Binding, Gene and Heart. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • MAP3K7IP2
    • Binding
    • Gene
    • Heart
    • Search
    • Tab2
    • Human
    • Location
    • Chromosome
    • Protein
    • Bp
    • Chr
    • Map3k7
  • map3k7ip2
    • Binding
    • Gene
    • Heart
    • Search
    • Tab2
    • Human
    • Location
    • Chromosome
    • Protein
    • Bp
    • Chr
    • Map3k7
  • gene
    • Location
    • Chromosome
    • Map3k7ip2
    • Protein
    • Bp
    • Chr
    • Map3k7
    • Binding
    • End
    • Factor
    • Jnk
    • Nuclear
  • map3k7
    • Protein
    • Tab1
    • Activation
    • Binding
    • Development
    • Factor
    • Function
    • Induced
    • Jnk
    • Nuclear
    • Receptor
    • Search
  • nuclear factor kappab
    • Factor
    • Jnk
    • Nuclear
    • Gene
    • Map3k7
    • Binding
    • Development
    • End
    • Function
    • Heart
    • Induced
    • Q99k90
  • jnk
    • Nuclear
    • Map3k7
    • Binding
    • Development
    • End
    • Function
    • Heart
    • Q99k90
    • Q9nyj8
    • Receptor
    • Search
    • Tab2
  • protein
    • Available
    • Pdb
    • Tab1
    • Uniprot
    • Human
    • Binding
    • Development
    • Function
    • Q99k90
    • Q9nyj8
    • Receptor
    • Search
  • nuclear receptor co-repressor 1
    • Factor
    • Jnk
    • Tab1
    • Binding
    • Development
    • End
    • Function
    • Heart
    • Q99k90
    • Q9nyj8
    • Receptor
    • Search

Connections between topic areas Semantic bridges

For MAP3K7IP2, one of the stronger structural bridges in this analysis connects MAP3K7IP2 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
MAP3K7IP2Overview · splits 9 ⟂ 16
MAP3K7IP2Interactions · splits 17 ⟂ 8

Map overview Semantic statistics

MAP3K7IP2

Nodes25
Edges24
Triples92
Avg. degree1.92
Density0.08
Components1

Source & methodology

TTTA analyzes the structure around MAP3K7IP2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — MAP3K7IP2 · EN edition · Analysis: TopicsToTalkAbout

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