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Methamphetamine

Methamphetamine is a central nervous system (CNS) stimulant that is primarily used as a recreational or performance-enhancing drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder (ADHD). It has also been researched as a potential treatment for traumatic brain injury. Methamphetamine was discovered in 1893 and…

History, Community, Culture & Applications

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Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
Addiction liability
Very high
AHFS/Drugs.com
Monograph
ATC code
N06BA03 (WHO)
Bioavailability
Oral: 67% Intranasal: 79% Inhalation: 67–90% Intravenous: 100%
Boiling point
212 °C (414 °F) at 760 mmHg

Topics to explore

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Overview

Uses

Contraindications

Adverse effects

Overdose

Interactions

Pharmacology

Chemistry

History, society, and culture

Trafficking

Legal status

Research

Advanced semantic analysis

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Map overview Semantic statistics

Methamphetamine

Nodes418
Edges417
Triples278
Avg. degree2
Density0.004785
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Methamphetamine

Top relations

related to history · 25
Methamphetamine → Akira Ogata, Amphetamine, Berlin-based Temmler, By, From, German, Germany, Göring's, Herman-Göring-Pills, Hermann-Göring-Pillen, Historian, However, It, Japanese, Kamieński, Lazăr Edeleanu, Nagai Nagayoshi, Pervitin, Romanian, Shortly
related to Trafficking · 25
Methamphetamine → Asia-Pacific, Australia, Canadian, Cantonese Chinese, China, Concerning, East, Golden Triangle, Guangzhou, It, Japan, Myanmar, New Zealand, Pacific, Sam Gor, Shan State, Southeast Asia, Southern China, Taiwan, Thailand
related to Pharmacodynamics · 18
Methamphetamine → Activation, Ca2, CAMK, DAT, EAAT2, GPCR, In, NET, Other, PKA, PKC, SERT, SLC22A3, SLC22A5, TAAR1, This, VMAT2, When
see also · 16
Methamphetamine → AustraliaMethamphetamine, Bangladesh, Breaking Bad, Drug, Harm, Illegal, Meth, Montana-based, Native AmericansMethamphetamine, Non-steroidal, PhilippinesMethamphetamine, Public, Southeast Asian, TV, United StatesMontana Meth Project, Use
related to Addiction · 11
Methamphetamine → CREB, Current, D1-type, G9a, It, NFκB, Once, Since, Sufficiently, The, These
related to Medical · 11
Methamphetamine → Adderall, ADHD, Although, Desoxyn, FDA, FDA-approved, In, OTC, This, To, United States
Legal status · 10
Methamphetamine → AU: S8 (Controlled drug), BR: Class F2 (Prohibited psychotropics), CA: Schedule I, DE: Anlage II (Authorized trade only, not prescriptible), EU: Rx-only, NZ: Class A, SE: Förteckning I, UK: Class A, UN: Psychotropic Schedule II, US: Schedule II
has treatment · 9
Methamphetamine → Acute, Antipsychotics, Beta, Blood, CNS, Forced, Hypertension, The, There
related to Neurotoxicity · 9
Methamphetamine → Excitotoxicity, In, It, Magnetic, Moreover, N-acetylaspartate, Parkinson's, UPS, Withdrawal
related to Pharmacokinetics · 9
Methamphetamine → Among, Because, CoA, CYP2D6, Following, Following IV, N-acyltransferase, The, When

Important terminology Word statistics

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Important terminology

use drug may effects also addiction brain amphetamine withdrawal dextromethamphetamine united psychosis users states stimulant high treatment known levomethamphetamine symptoms

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Methamphetamine3D model (JSmol)Interactive image1.00infobox
MethamphetamineAddiction liabilityVery high1.00infobox
MethamphetamineAHFS/Drugs.comMonograph1.00infobox
MethamphetamineATC codeN06BA03 (WHO)1.00infobox
MethamphetamineBioavailabilityOral: 67% Intranasal: 79% Inhalation: 67–90% Intravenous: 100%1.00infobox
MethamphetamineBoiling point212 °C (414 °F) at 760 mmHg1.00infobox
MethamphetamineCAS Number537-46-2 Y1.00infobox
MethamphetamineCAS Number(dl)-Methamphetamine hydrochloride: 300-42-5 Y1.00infobox
MethamphetamineChEBICHEBI:6809 Y1.00infobox
MethamphetamineChEMBLChEMBL1201201 Y1.00infobox
MethamphetamineChemSpider1169 Y1.00infobox
MethamphetamineChiralityRacemic mixture1.00infobox
MethamphetamineCompTox Dashboard (EPA)DTXSID80371281.00infobox
MethamphetamineDependence liabilityPhysical: None1.00infobox
MethamphetamineDependence liabilityPsychological: Very high1.00infobox
MethamphetamineDrug classStimulant; Serotonin–norepinephrine–dopamine releasing agent1.00infobox
MethamphetamineDrugBankDB01577 Y1.00infobox
MethamphetamineDuration of action8–12 hours1.00infobox
MethamphetamineECHA InfoCard100.007.8821.00infobox
MethamphetamineElimination half-life9–12 hours (range 5–30 hours); irrespective of route1.00infobox
MethamphetamineExcretionPrimarily kidney1.00infobox
MethamphetamineFormulaC10H15N1.00infobox
MethamphetamineIUPHAR/BPS48031.00infobox
MethamphetamineKEGGD08187 Y1.00infobox
MethamphetamineLegal statusAU: S8 (Controlled drug)1.00infobox
MethamphetamineLegal statusBR: Class F2 (Prohibited psychotropics)1.00infobox
MethamphetamineLegal statusCA: Schedule I1.00infobox
MethamphetamineLegal statusDE: Anlage II (Authorized trade only, not prescriptible)1.00infobox
MethamphetamineLegal statusNZ: Class A1.00infobox
MethamphetamineLegal statusUK: Class A1.00infobox

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