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Monoamine oxidase B: Differences between MAO-A and MAO-B, Roles in disease and aging & Overview

Monoamine oxidase B (MAO-B) is an enzyme that in humans is encoded by the MAOB gene.

Language: English [EN]
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Monoamine oxidase B topic overview

The analysis highlights Differences between MAO-A and MAO-B, Roles in disease and aging and Overview as prominent areas in the source structure around Monoamine oxidase B.

Related topics
76
Source areas
4
Connected nodes
80
Extracted relationships
92
Related term clusters
21
Bridge connections
80

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 26 topics
Differences between MAO-A and MAO-B · 21 topics
Roles in disease and aging · 20 topics
Structure and function · 9 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

1.4.3.21
↗
1.4.3.4
↗
Aliases
MAOB, Monoamine oxidase B
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GOS, 1OJ9, 1OJA, 1OJC, 1OJD, 1S2Q, 1S2Y, 1S3B, 1S3E, 2BK3, 2BK4, 2BK5, 2BYB, 2C64, 2C65, 2C66, 2C67, 2C70,…
Band
Xp11.3 · X A1.2|X 11.88 cM
Bgee
saphenous vein · external globus pallidus · decidua · tail of epididymis · middle frontal gyrus

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Monoamine oxidase B
3Benzylamine · Phenethylamine · Knockout mouse
3Outer mitochondrial membrane · Enzyme · Gene
3MAO-B inhibitor · Parkinson's disease · Alzheimer's disease
6Monoamine oxidase · Oxidative deamination · Xenobiotic

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure and function

Differences between MAO-A and MAO-B

Roles in disease and aging

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Monoamine oxidase B connects Entity context

The extracted context around Monoamine oxidase B shows recurring relationship patterns in the source. For example, Monoamine oxidase B → dopamine catabolic process, electron transfer activity, electron transport chain, extracellular exosome, flavin adenine dinucleotide binding, hydrogen peroxide biosynthetic process, integral component of membrane, membrane, mitochondrial envelope, mitochondrial inner membrane, mitochondrial outer membrane, mitochondrion, negative regulation of serotonin secretion, neurotransmitter catabolic process, oxidoreductase activity, positive regulation of dopamine metabolic process, primary amine oxidase activity, protein homodimerization activity, response to aluminum ion, response to corticosterone Another extracted example is Monoamine oxidase B → decidua, Epithelium of choroid plexus, epithelium of small intestine, external globus pallidus, hypothalamus, interventricular septum, islet of Langerhans, left lobe of liver, left ovary, liver, medial dorsal nucleus, middle frontal gyrus, myocardium of ventricle, nasal epithelium, olfactory epithelium, right lobe of liver, saphenous vein, superior vestibular nucleus, tail of epididymis, upper respiratory tract. Use these groups to spot repeated connection types before inspecting the individual relationships.

Monoamine oxidase B

Top relations

Gene ontology · 26
Monoamine oxidase B → dopamine catabolic process, electron transfer activity, electron transport chain, extracellular exosome, flavin adenine dinucleotide binding, hydrogen peroxide biosynthetic process, integral component of membrane, membrane, mitochondrial envelope, mitochondrial inner membrane, mitochondrial outer membrane, mitochondrion, negative regulation of serotonin secretion, neurotransmitter catabolic process, oxidoreductase activity, positive regulation of dopamine metabolic process, primary amine oxidase activity, protein homodimerization activity, response to aluminum ion, response to corticosterone
Bgee · 20
Monoamine oxidase B → decidua, Epithelium of choroid plexus, epithelium of small intestine, external globus pallidus, hypothalamus, interventricular septum, islet of Langerhans, left lobe of liver, left ovary, liver, medial dorsal nucleus, middle frontal gyrus, myocardium of ventricle, nasal epithelium, olfactory epithelium, right lobe of liver, saphenous vein, superior vestibular nucleus, tail of epididymis, upper respiratory tract
RNA expression pattern · 20
Monoamine oxidase B → decidua, Epithelium of choroid plexus, epithelium of small intestine, external globus pallidus, hypothalamus, interventricular septum, islet of Langerhans, left lobe of liver, left ovary, liver, medial dorsal nucleus, middle frontal gyrus, myocardium of ventricle, nasal epithelium, olfactory epithelium, right lobe of liver, saphenous vein, superior vestibular nucleus, tail of epididymis, upper respiratory tract
Band · 2
Monoamine oxidase B → X A1.2|X 11.88 cM, Xp11.3
Chr. · 2
Monoamine oxidase B → X chromosome (human), X chromosome (mouse)
End · 2
Monoamine oxidase B → 16,683,605 bp, 43,882,450 bp
1.4.3.21 · 1
Monoamine oxidase B → ↗
1.4.3.4 · 1
Monoamine oxidase B → ↗
Aliases · 1
Monoamine oxidase B → MAOB, Monoamine oxidase B
Available structures · 1
Monoamine oxidase B → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GOS, 1OJ9, 1OJA, 1OJC, 1OJD, 1S2Q, 1S2Y, 1S3B, 1S3E, 2BK3, 2BK4, 2BK5, 2BYB, 2C64, 2C65, 2C66, 2C67, 2C70,…

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

mao-b mao-a gene inhibitors oxidase bp monoamine human dopamine also chr band protein enzyme activity chromosome catabolism disease maob substrate

Monoamine oxidase B relationships Subject–Predicate–Object triples

TTTA extracted 92 structured relationships around Monoamine oxidase B. Examples in this analysis include Monoamine oxidase B → 1.4.3.21 → ↗ and Monoamine oxidase B → Aliases → MAOB, Monoamine oxidase B. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Monoamine oxidase B1.4.3.21↗1.00infobox
Monoamine oxidase B1.4.3.4↗1.00infobox
Monoamine oxidase BAliasesMAOB, Monoamine oxidase B1.00infobox
Monoamine oxidase BAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GOS, 1OJ9, 1OJA, 1OJC, 1OJD, 1S2Q, 1S2Y, 1S3B, 1S3E, 2BK3, 2BK4, 2BK5, 2BYB, 2C64, 2C65, 2C66, 2C67, 2C70,…1.00infobox
Monoamine oxidase BBandXp11.31.00infobox
Monoamine oxidase BBandX A1.2|X 11.88 cM1.00infobox
Monoamine oxidase BBgeesaphenous vein1.00infobox
Monoamine oxidase BBgeeexternal globus pallidus1.00infobox
Monoamine oxidase BBgeedecidua1.00infobox
Monoamine oxidase BBgeetail of epididymis1.00infobox
Monoamine oxidase BBgeemiddle frontal gyrus1.00infobox
Monoamine oxidase BBgeehypothalamus1.00infobox
Monoamine oxidase BBgeeleft ovary1.00infobox
Monoamine oxidase BBgeesuperior vestibular nucleus1.00infobox
Monoamine oxidase BBgeeliver1.00infobox
Monoamine oxidase BBgeeright lobe of liver1.00infobox
Monoamine oxidase BBgeeepithelium of small intestine1.00infobox
Monoamine oxidase BBgeeleft lobe of liver1.00infobox
Monoamine oxidase BBgeeEpithelium of choroid plexus1.00infobox
Monoamine oxidase BBgeeupper respiratory tract1.00infobox
Monoamine oxidase BBgeenasal epithelium1.00infobox
Monoamine oxidase BBgeeolfactory epithelium1.00infobox
Monoamine oxidase BBgeemedial dorsal nucleus1.00infobox
Monoamine oxidase BBgeeislet of Langerhans1.00infobox
Monoamine oxidase BBgeeinterventricular septum1.00infobox
Monoamine oxidase BBgeemyocardium of ventricle1.00infobox
Monoamine oxidase BBioGPSMore reference expression data1.00infobox
Monoamine oxidase BChr.X chromosome (human)1.00infobox
Monoamine oxidase BChr.X chromosome (mouse)1.00infobox
Monoamine oxidase BDatabasesNCBI: entry; OMA: entry1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Monoamine oxidase B bring nearby vocabulary together. In this analysis, examples include Oxidase, Encoded and Humans. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Monoamine oxidase B
    • Oxidase
    • Encoded
    • Humans
    • Enzyme
    • Gene
    • Maob
    • Selective
    • Also
    • Catabolism
    • Flavin
    • Location
    • Mao-a
  • monoamine oxidase b
    • Oxidase
    • Encoded
    • Humans
    • Enzyme
    • Gene
    • Maob
    • Selective
    • Location
    • Chromosome
    • Protein
    • Activity
    • Also
  • gene
    • Oxidase
    • Location
    • Maob
    • Chromosome
    • Bp
    • Chr
    • Human
    • Monoamine
    • Humans
    • End
    • Flavin
    • Mouse
  • monoamine oxidase
    • Oxidase
    • Encoded
    • Humans
    • Enzyme
    • Gene
    • Maob
    • Selective
    • Location
    • Chromosome
    • Protein
    • Activity
    • Also
  • monoamine oxidase a
    • Oxidase
    • Encoded
    • Humans
    • Enzyme
    • Gene
    • Maob
    • Selective
    • Location
    • Chromosome
    • Protein
    • Activity
    • Also
  • mao-b inhibitors
    • Mao-a
    • Inhibitors
    • Mao-b
    • Selective
    • Activity
    • Brain
    • Disease
    • Parkinson's
    • Gene
    • Human
    • Levels
    • Dopamine
  • catecholaminergic activity enhancer
    • Location
    • Maob
    • Chromosome
    • Bp
    • Chr
    • Human
    • Also
    • Oxidase
    • Mao-b
    • Gene
    • Humans
    • Membrane
  • differences between mao-a and mao-b
    • Inhibitors
    • Also
    • Mao-a
    • Mao-b
    • Dopamine
    • Activity
    • Brain
    • Disease
    • Parkinson's
    • Gene
    • Levels
    • Selective

Connections between topic areas Semantic bridges

For Monoamine oxidase B, one of the stronger structural bridges in this analysis connects Monoamine oxidase B with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Monoamine oxidase B — Overview · splits 54 ⟂ 27
Monoamine oxidase B — Differences between MAO-A and MAO-B · splits 59 ⟂ 22
Monoamine oxidase B — Roles in disease and aging · splits 60 ⟂ 21
Monoamine oxidase B — Structure and function · splits 71 ⟂ 10

Map overview Semantic statistics

Monoamine oxidase B

Nodes81
Edges80
Triples92
Avg. degree1.98
Density0.024691
Components1

Source & methodology

TTTA analyzes the structure around Monoamine oxidase B to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Differences between MAO-A and MAO-B, Roles in disease and aging & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Monoamine oxidase B · EN edition · Analysis: TopicsToTalkAbout

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