Glyceraldehyde 3-phosphate dehydrogenase

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Glyceraldehyde 3-phosphate dehydrogenase topic overview

The analysis highlights Applications, Function and Interactions as prominent areas in the source structure around Glyceraldehyde 3-phosphate dehydrogenase.

Related topics: 137
Source areas: 8
Connected nodes: 145
Extracted relationships: 86
Related term clusters: 33
Bridge connections: 145

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 36 topics

Interactions · 36 topics

Overview · 21 topics

Clinical significance · 18 topics

Reaction · 10 topics

Structure · 9 topics

Use as loading control · 5 topics

Cellular distribution · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

1.2.1.12: ↗
Aliases: GAPDH, GAPD, G3PD, HEL-S-162eP, glyceraldehyde-3-phosphate dehydrogenase
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1U8F, 1ZNQ, 3GPD, 4WNC, 4WNI
Band: 12p13.31
Bgee: frontal pole · pons · paraflocculus of cerebellum · Brodmann area 10 · triceps brachii muscle
BioGPS: n/a

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Glyceraldehyde 3-phosphate dehydrogenase

3Glyceraldehyde 3-phosphate · Aldehyde · Carboxylic acid

11Enzyme Commission number · Enzyme · Kilodaltons

4Exergonic · Endergonic · Phosphate

10Cytoplasm · Tetramer · KDa

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Structure

Reaction

Use as loading control

Cellular distribution

Clinical significance

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Glyceraldehyde 3-phosphate dehydrogenase connects Entity context

The extracted context around Glyceraldehyde 3-phosphate dehydrogenase shows recurring relationship patterns in the source. For example, Glyceraldehyde 3-phosphate dehydrogenase → antimicrobial humoral immune response mediated by antimicrobial peptide, apoptotic process, aspartic-type endopeptidase inhibitor activity, canonical glycolysis, cellular response to interferon-gamma, cytoplasm, cytoskeleton, cytosol, disordered domain specific binding, extracellular exosome, extracellular matrix, GAIT complex, gluconeogenesis, glucose metabolic process, glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity, glycolytic process, identical protein binding, intracellular membrane-bounded organelle, lipid droplet, membrane Another extracted example is Glyceraldehyde 3-phosphate dehydrogenase → body of tongue, Brodmann area 10, Brodmann area 46, deltoid muscle, frontal pole, lateral nuclear group of thalamus, paraflocculus of cerebellum, pons, Skeletal muscle tissue of biceps brachii, triceps brachii muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 43

Glyceraldehyde 3-phosphate dehydrogenase → antimicrobial humoral immune response mediated by antimicrobial peptide, apoptotic process, aspartic-type endopeptidase inhibitor activity, canonical glycolysis, cellular response to interferon-gamma, cytoplasm, cytoskeleton, cytosol, disordered domain specific binding, extracellular exosome, extracellular matrix, GAIT complex, gluconeogenesis, glucose metabolic process, glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity, glycolytic process, identical protein binding, intracellular membrane-bounded organelle, lipid droplet, membrane

Bgee · 10

Glyceraldehyde 3-phosphate dehydrogenase → body of tongue, Brodmann area 10, Brodmann area 46, deltoid muscle, frontal pole, lateral nuclear group of thalamus, paraflocculus of cerebellum, pons, Skeletal muscle tissue of biceps brachii, triceps brachii muscle

RNA expression pattern · 10

related to Metabolic · 2

Glyceraldehyde 3-phosphate dehydrogenase → D-glycerate, GAPDH

1.2.1.12 · 1

Glyceraldehyde 3-phosphate dehydrogenase → ↗

Aliases · 1

Glyceraldehyde 3-phosphate dehydrogenase → GAPDH, GAPD, G3PD, HEL-S-162eP, glyceraldehyde-3-phosphate dehydrogenase

Available structures · 1

Glyceraldehyde 3-phosphate dehydrogenase → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1U8F, 1ZNQ, 3GPD, 4WNC, 4WNI

Band · 1

Glyceraldehyde 3-phosphate dehydrogenase → 12p13.31

BioGPS · 1

Glyceraldehyde 3-phosphate dehydrogenase → n/a

Chr. · 1

Glyceraldehyde 3-phosphate dehydrogenase → Chromosome 12 (human)

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gapdh glycolysis function human protein transcription apoptosis dehydrogenase reaction pathway cellular metabolic phosphorylation cells step energy gene functions 12 binding

Glyceraldehyde 3-phosphate dehydrogenase relationships Subject–Predicate–Object triples

TTTA extracted 86 structured relationships around Glyceraldehyde 3-phosphate dehydrogenase. Examples in this analysis include Glyceraldehyde 3-phosphate dehydrogenase → 1.2.1.12 → ↗ and Glyceraldehyde 3-phosphate dehydrogenase → Aliases → GAPDH, GAPD, G3PD, HEL-S-162eP, glyceraldehyde-3-phosphate dehydrogenase. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
Glyceraldehyde 3-phosphate dehydrogenase	1.2.1.12	↗	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Aliases	GAPDH, GAPD, G3PD, HEL-S-162eP, glyceraldehyde-3-phosphate dehydrogenase	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1U8F, 1ZNQ, 3GPD, 4WNC, 4WNI	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Band	12p13.31	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Bgee	frontal pole	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Bgee	pons	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Bgee	paraflocculus of cerebellum	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Bgee	Brodmann area 10	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Bgee	triceps brachii muscle	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Bgee	deltoid muscle	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Bgee	Skeletal muscle tissue of biceps brachii	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Bgee	Brodmann area 46	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Bgee	lateral nuclear group of thalamus	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Bgee	body of tongue	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	BioGPS	n/a	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Chr.	Chromosome 12 (human)	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Databases	NCBI: entry; OMA: entry	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	End	6,538,374 bp	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Ensembl	ENSG00000111640	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Entrez	2597	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Enzyme activity	Enzyme activityEC #BRENDAExPASyKEGGMetaCyc1.2.1.12↗↗↗↗	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	External IDs	OMIM: 138400; MGI: 5434255; GeneCards: GAPDH	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Gene location (Human)	Gene location (Human)Chr.Chromosome 12 (human)Band12p13.31Start6,534,512 bpEnd6,538,374 bp	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Gene ontology	transferase activity	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Gene ontology	microtubule binding	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Gene ontology	NAD binding	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Gene ontology	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Gene ontology	protein binding	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Gene ontology	peptidyl-cysteine S-nitrosylase activity	1.00	infobox
Glyceraldehyde 3-phosphate dehydrogenase	Gene ontology	NADP binding	1.00	infobox

Related concept clusters Related term clusters

The concept neighborhoods around Glyceraldehyde 3-phosphate dehydrogenase bring nearby vocabulary together. In this analysis, examples include Complex, Glucose and Binding. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

Glyceraldehyde 3-phosphate dehydrogenase
- Complex
- Glucose
- Binding
- Human
- Bp
- Protein
- Nucleus
- Interactions
- Membrane
- Transport
- Apoptosis
- Cellular
glyceraldehyde 3-phosphate dehydrogenase
- Complex
- Glucose
- Binding
- Human
- Bp
- Protein
- Nucleus
- Interactions
- Membrane
- Transport
- Apoptosis
- Cellular
glycolysis
- Cytosol
- Glucose
- Cellular
- Metabolic
- Step
- Reaction
- Bp
- Complex
- Nucleus
- Acid
- Expressed
- Glycolytic
glucose
- Glycolytic
- Complex
- Nucleus
- Cytosol
- Membrane
- Binding
- Nuclear
- Thus
- Glycolysis
- Step
- Cells
- Protein
apoptosis
- Transport
- Interactions
- Function
- Protein
- Membrane
- Binding
- Metabolic
- Nuclear
- Stress
- Transcription
- Dehydrogenase
- Functions
axoplasmic transport
- Apoptosis
- Interactions
- Function
- Protein
- Membrane
- Binding
- Metabolic
- Nuclear
- Transcription
- Dehydrogenase
- Functions
- Proteins
carboxylic acid
- Reaction
- Binding
- Phosphorylation
- Bp
- Adhesion
- Interactions
- Kegg
- Transport
- Apoptosis
- Cellular
- Metabolic
- Transcription
moonlighting functions
- Interactions
- Binding
- Transport
- Cells
- Protein
- Bp
- Gapdh
- Complex
- Nucleus
- Acid
- Glucose
- Glycolytic

Connections between topic areas Semantic bridges

For Glyceraldehyde 3-phosphate dehydrogenase, one of the stronger structural bridges in this analysis connects Glyceraldehyde 3-phosphate dehydrogenase with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Glyceraldehyde 3-phosphate dehydrogenase — Function · splits 109 ⟂ 37

Glyceraldehyde 3-phosphate dehydrogenase — Interactions · splits 109 ⟂ 37

Glyceraldehyde 3-phosphate dehydrogenase — Overview · splits 124 ⟂ 22

Glyceraldehyde 3-phosphate dehydrogenase — Clinical significance · splits 127 ⟂ 19

Glyceraldehyde 3-phosphate dehydrogenase — Reaction · splits 135 ⟂ 11

Glyceraldehyde 3-phosphate dehydrogenase — Structure · splits 136 ⟂ 10

Glyceraldehyde 3-phosphate dehydrogenase — Use as loading control · splits 140 ⟂ 6

Glyceraldehyde 3-phosphate dehydrogenase — Cellular distribution · splits 143 ⟂ 3

Map overview Semantic statistics

Glyceraldehyde 3-phosphate dehydrogenase

Nodes146

Edges145

Triples86

Avg. degree1.99

Density0.013699

Components1

Source & methodology

TTTA analyzes the structure around Glyceraldehyde 3-phosphate dehydrogenase to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Function & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Glyceraldehyde 3-phosphate dehydrogenase · EN edition · Analysis: TopicsToTalkAbout

Glyceraldehyde 3-phosphate dehydrogenase: Applications, Function & Interactions

Glyceraldehyde 3-phosphate dehydrogenase topic overview

What this topic covers Research coverage

Key facts & relationships

Start with your topic. Discover where to go next.

Questions to explore

Explore all related topics Closing gaps

Overview

Structure

Reaction

Function

Use as loading control

Cellular distribution

Clinical significance

Interactions

For the semantics nerds

Advanced semantic analysis

How Glyceraldehyde 3-phosphate dehydrogenase connects Entity context

Glyceraldehyde 3-phosphate dehydrogenase

Top relations

Important terminology

Important terminology

Glyceraldehyde 3-phosphate dehydrogenase relationships Subject–Predicate–Object triples

Related concept clusters Related term clusters

Connections between topic areas Semantic bridges

Map overview Semantic statistics

Glyceraldehyde 3-phosphate dehydrogenase

Source & methodology