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Morpheein

Morpheeins are proteins that can form two or more different homo-oligomers (morpheein forms), but must come apart and change shape to convert between forms. The alternate shape may reassemble to a different oligomer. The shape of the subunit dictates which oligomer is formed. Each oligomer has a finite number of subunits (stoichiometry). Morpheeins can…

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Implications for teaching about protein structure-function relationships

Quaternary structureMichaelis-Menten kineticsHysteresisSpecific activity
4 related topics

Implications for allosteric regulation

Sequential modelGlutamate dehydrogenase
2 related topics

Implications for understanding the structural basis for disease

PorphyriaPorphobilinogen synthase
2 related topics

Overview

ProteinsOligomersStoichiometryPrionsAmyloid
9 related topics

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Overview

Implications for allosteric regulation

Implications for teaching about protein structure-function relationships

Implications for understanding the structural basis for disease

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Map overview Semantic statistics

Morpheein

Nodes22
Edges21
Triples26
Avg. degree1.91
Density0.090909
Components1

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Morpheein

Top relations

related to Implications for allosteric regulation · 12
Morpheein → Changeux, Filmer, Friedrich, However, Koshland, Kurganov, Monod, MWC, Nemethy, Nonetheless, The, Wyman
related to Implications for understanding the structural basis for disease · 7
Morpheein → ALAD, Alzheimer's, An, Creutzfeldt, In, Jakob, The
related to Implications for drug discovery · 4
Morpheein → An, Conformational, Protein, The
related to Implications for teaching about protein structure-function relationships · 3
Morpheein → It, Michaelis-Menten, The

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Important terminology

morpheeins protein equilibrium forms different oligomers proteins conformational oligomer model may shape allosteric regulation disease discovery basis one two drug

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Morpheeinrelated to Implications for allosteric regulationThe0.60section
Morpheeinrelated to Implications for allosteric regulationMonod0.60section
Morpheeinrelated to Implications for allosteric regulationWyman0.60section
Morpheeinrelated to Implications for allosteric regulationChangeux0.60section
Morpheeinrelated to Implications for allosteric regulationMWC0.60section
Morpheeinrelated to Implications for allosteric regulationHowever0.60section
Morpheeinrelated to Implications for allosteric regulationKoshland0.60section
Morpheeinrelated to Implications for allosteric regulationNemethy0.60section
Morpheeinrelated to Implications for allosteric regulationFilmer0.60section
Morpheeinrelated to Implications for allosteric regulationNonetheless0.60section
Morpheeinrelated to Implications for allosteric regulationKurganov0.60section
Morpheeinrelated to Implications for allosteric regulationFriedrich0.60section

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