Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Factor X

Coagulation factor X (EC 3.4.21.6), or Stuart factor, is an enzyme of the coagulation cascade, encoded in humans by F10 gene. It is a serine endopeptidase (protease group S1, PA clan). Factor X is synthesized in the liver and requires vitamin K for its synthesis.

Applications & Art

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around Factor X. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3.4.21.6
Aliases
F10, FX, FXA, coagulation factor X
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C5M, 1EZQ, 1F0R, 1F0S, 1FAX, 1FJS, 1G2L, 1G2M, 1HCG, 1IOE, 1IQE, 1IQF, 1IQG, 1IQH, 1IQI, 1IQJ, 1IQK, 1IQL,…
Band
13q34 · 8 A1.1|8 5.73 cM
Bgee
right lobe of liver · stromal cell of endometrium · right auricle of heart · canal of the cervix · ectocervix
BioGPS
More reference expression data

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Structure

Genetics

Role in disease

Therapeutic use

Use in biochemistry

Factor Xa

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Factor X

Nodes78
Edges77
Triples175
Avg. degree1.97
Density0.025641
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Factor X

Top relations

related to Structure · 22
Factor X → Asp189, Factor Xa, It, L-shaped, May, Phe174, S1, S2, S3, S4, Ser195, The, The S1, The S2, The S3, The S4, To, Trp215, Typically, Tyr228
Bgee · 20
Factor X → blood, bone marrow, canal of the cervix, ectocervix, embryo, epithelium of small intestine, fetal liver hematopoietic progenitor cell, gallbladder, gastric mucosa, granulocyte, left lobe of liver, left ovary, left uterine tube, right auricle of heart, right coronary artery, right lobe of liver, right ovary, sexually immature organism, stromal cell of endometrium, yolk sac
Gene ontology · 20
Factor X → blood coagulation, blood coagulation, extrinsic pathway, calcium ion binding, endoplasmic reticulum lumen, endoplasmic reticulum to Golgi vesicle-mediated transport, extracellular region, extracellular space, Golgi lumen, hemostasis, hydrolase activity, intrinsic component of external side of plasma membrane, peptidase activity, phospholipid binding, plasma membrane, positive regulation of cell migration, positive regulation of protein kinase B signaling, protein binding, proteolysis, serine-type endopeptidase activity, serine-type peptidase activity
RNA expression pattern · 20
Factor X → blood, bone marrow, canal of the cervix, ectocervix, embryo, epithelium of small intestine, fetal liver hematopoietic progenitor cell, gallbladder, gastric mucosa, granulocyte, left lobe of liver, left ovary, left uterine tube, right auricle of heart, right coronary artery, right lobe of liver, right ovary, sexually immature organism, stromal cell of endometrium, yolk sac
related to Therapeutic use · 18
Factor X → Behring, Bio Products Laboratory, CHMP, Coagadex, COMP, CSL Behring, EU, Factor, Factors II, FDA, IX, Kcentra, March, October, Proteins, There, United States, VII
related to history · 11
Factor X → American, As, At, British, Miss Audrey Prower, Morawitz, Mr Rufus Stuart, Paul Morawitz, That, Those, Thrombokinase
related to External links · 9
Factor X → April, Canadian Hemophilia Society, EMBL, European Molecular Biology Laboratory, Factor, MEROPS, S01, Summary, Xa
related to Factor Xa · 9
Factor X → Factor, Factor II, Factor IIa, Factor Xa, Factor Xa/Va, TF, The, These, Traditional
related to Use in biochemistry · 7
Factor X → After, IDGR, IEGR, Ile-Glu/Asp-Gly-Arg, Its, The, Xa
related to Role in disease · 6
Factor X → Apart, As, Deficiency, For, In, Inborn

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

factor xa coagulation thrombin enzyme prothrombin complex protein human bp gene thrombokinase activated activity pathway chr prothrombinase band chromosome 13

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Factor X3.4.21.61.00infobox
Factor XAliasesF10, FX, FXA, coagulation factor X1.00infobox
Factor XAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C5M, 1EZQ, 1F0R, 1F0S, 1FAX, 1FJS, 1G2L, 1G2M, 1HCG, 1IOE, 1IQE, 1IQF, 1IQG, 1IQH, 1IQI, 1IQJ, 1IQK, 1IQL,…1.00infobox
Factor XBand13q341.00infobox
Factor XBand8 A1.1|8 5.73 cM1.00infobox
Factor XBgeeright lobe of liver1.00infobox
Factor XBgeestromal cell of endometrium1.00infobox
Factor XBgeeright auricle of heart1.00infobox
Factor XBgeecanal of the cervix1.00infobox
Factor XBgeeectocervix1.00infobox
Factor XBgeegastric mucosa1.00infobox
Factor XBgeeright ovary1.00infobox
Factor XBgeeleft ovary1.00infobox
Factor XBgeeright coronary artery1.00infobox
Factor XBgeeleft uterine tube1.00infobox
Factor XBgeeleft lobe of liver1.00infobox
Factor XBgeeyolk sac1.00infobox
Factor XBgeegallbladder1.00infobox
Factor XBgeeembryo1.00infobox
Factor XBgeefetal liver hematopoietic progenitor cell1.00infobox
Factor XBgeeepithelium of small intestine1.00infobox
Factor XBgeeblood1.00infobox
Factor XBgeesexually immature organism1.00infobox
Factor XBgeegranulocyte1.00infobox
Factor XBgeebone marrow1.00infobox
Factor XBioGPSMore reference expression data1.00infobox
Factor XChr.Chromosome 13 (human)1.00infobox
Factor XChr.Chromosome 8 (mouse)1.00infobox
Factor XDatabasesNCBI: entry; OMA: entry1.00infobox
Factor XEnd113,149,529 bp1.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.