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Coagulation factor V (Factor V), also less commonly known as proaccelerin or labile factor, is a protein involved in coagulation, encoded, in humans, by F5 gene. In contrast to most other coagulation factors, it is not enzymatically active but functions as a cofactor. Factor V deficiency leads to predisposition for hemorrhage, while some mutations (most…
The analysis highlights History, Structure and Physiology as prominent areas in the source structure around Factor V.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Factor V shows recurring relationship patterns in the source. For example, Factor V → blood circulation, blood coagulation, COPII vesicle coating, COPII-coated ER to Golgi transport vesicle, copper ion binding, endoplasmic reticulum, endoplasmic reticulum lumen, endoplasmic reticulum to Golgi vesicle-mediated transport, endoplasmic reticulum-Golgi intermediate compartment membrane, extracellular region, extracellular space, extracellular vesicle, Golgi apparatus, Golgi membrane, hemostasis, membrane, metal ion binding, plasma membrane, platelet alpha granule, platelet alpha granule lumen Another extracted example is Factor V → However, II, III, IV, Mary, Morawitz, Most, Norway, Norwegian, Owren, Paul Morawitz, Paul Owren, Second World War, She, The, The Lancet, They, Until, Using Mary's. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
factor protein coagulation gene bp thrombin chr human band chromosome prothrombin activated f5 form owren leiden cofactor mutations thrombosis plasma
TTTA extracted 133 structured relationships around Factor V. Examples in this analysis include Factor V → Aliases → F5, FVL, PCCF, RPRGL1, THPH2, coagulation factor V and Factor V → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3S9C, 1CZS, 1CZV, 3P6Z, 3P70. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Factor V | Aliases | F5, FVL, PCCF, RPRGL1, THPH2, coagulation factor V | 1.00 | infobox |
| Factor V | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3S9C, 1CZS, 1CZV, 3P6Z, 3P70 | 1.00 | infobox |
| Factor V | Band | 1q24.2 | 1.00 | infobox |
| Factor V | Band | 1 H2.2|1 71.46 cM | 1.00 | infobox |
| Factor V | Bgee | right lobe of liver | 1.00 | infobox |
| Factor V | Bgee | Epithelium of choroid plexus | 1.00 | infobox |
| Factor V | Bgee | pancreatic ductal cell | 1.00 | infobox |
| Factor V | Bgee | placenta | 1.00 | infobox |
| Factor V | Bgee | optic nerve | 1.00 | infobox |
| Factor V | Bgee | monocyte | 1.00 | infobox |
| Factor V | Bgee | olfactory zone of nasal mucosa | 1.00 | infobox |
| Factor V | Bgee | blood | 1.00 | infobox |
| Factor V | Bgee | gallbladder | 1.00 | infobox |
| Factor V | Bgee | granulocyte | 1.00 | infobox |
| Factor V | Bgee | choroid plexus of fourth ventricle | 1.00 | infobox |
| Factor V | Bgee | left lobe of liver | 1.00 | infobox |
| Factor V | Bgee | ciliary body | 1.00 | infobox |
| Factor V | Bgee | lacrimal gland | 1.00 | infobox |
| Factor V | Bgee | iris | 1.00 | infobox |
| Factor V | Bgee | tibiofemoral joint | 1.00 | infobox |
| Factor V | Bgee | parotid gland | 1.00 | infobox |
| Factor V | BioGPS | More reference expression data | 1.00 | infobox |
| Factor V | Chr. | Chromosome 1 (human) | 1.00 | infobox |
| Factor V | Chr. | Chromosome 1 (mouse) | 1.00 | infobox |
| Factor V | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Factor V | End | 169,586,588 bp | 1.00 | infobox |
| Factor V | End | 164,047,846 bp | 1.00 | infobox |
| Factor V | Ensembl | ENSG00000198734 | 1.00 | infobox |
| Factor V | Entrez | 2153 | 1.00 | infobox |
| Factor V | External IDs | OMIM: 612309; MGI: 88382; GeneCards: F5 | 1.00 | infobox |
The concept neighborhoods around Factor V bring nearby vocabulary together. In this analysis, examples include Protein, Activated and Leiden. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Factor V, one of the stronger structural bridges in this analysis connects Factor V with History. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Factor V to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Structure & Physiology, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Factor V · EN edition · Analysis: TopicsToTalkAbout