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Factor X: Applications & Art

Coagulation factor X (EC 3.4.21.6), or Stuart factor, is an enzyme of the coagulation cascade, encoded in humans by F10 gene. It is a serine endopeptidase (protease group S1, PA clan). Factor X is synthesized in the liver and requires vitamin K for its synthesis.

Language: English [EN]
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Factor X topic overview

The analysis highlights Applications and Art as prominent areas in the source structure around Factor X.

Related topics
69
Source areas
8
Connected nodes
77
Extracted relationships
175
Concept neighborhoods
35
Bridge connections
77

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Factor Xa · 27 topics
Overview · 23 topics
Role in disease · 7 topics
Structure · 4 topics
Therapeutic use · 3 topics
Genetics · 2 topics
Interactions · 2 topics
Use in biochemistry · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3.4.21.6
Aliases
F10, FX, FXA, coagulation factor X
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C5M, 1EZQ, 1F0R, 1F0S, 1FAX, 1FJS, 1G2L, 1G2M, 1HCG, 1IOE, 1IQE, 1IQF, 1IQG, 1IQH, 1IQI, 1IQJ, 1IQK, 1IQL,…
Band
13q34 · 8 A1.1|8 5.73 cM
Bgee
right lobe of liver · stromal cell of endometrium · right auricle of heart · canal of the cervix · ectocervix
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Genetics

Role in disease

Therapeutic use

Use in biochemistry

Factor Xa

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Factor X connects Entity context

The extracted context around Factor X shows recurring relationship patterns in the source. For example, Factor X → Asp189, Factor Xa, It, L-shaped, May, Phe174, S1, S2, S3, S4, Ser195, The, The S1, The S2, The S3, The S4, To, Trp215, Typically, Tyr228 Another extracted example is Factor X → blood, bone marrow, canal of the cervix, ectocervix, embryo, epithelium of small intestine, fetal liver hematopoietic progenitor cell, gallbladder, gastric mucosa, granulocyte, left lobe of liver, left ovary, left uterine tube, right auricle of heart, right coronary artery, right lobe of liver, right ovary, sexually immature organism, stromal cell of endometrium, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

Factor X

Top relations

related to Structure · 22
Factor X → Asp189, Factor Xa, It, L-shaped, May, Phe174, S1, S2, S3, S4, Ser195, The, The S1, The S2, The S3, The S4, To, Trp215, Typically, Tyr228
Bgee · 20
Factor X → blood, bone marrow, canal of the cervix, ectocervix, embryo, epithelium of small intestine, fetal liver hematopoietic progenitor cell, gallbladder, gastric mucosa, granulocyte, left lobe of liver, left ovary, left uterine tube, right auricle of heart, right coronary artery, right lobe of liver, right ovary, sexually immature organism, stromal cell of endometrium, yolk sac
Gene ontology · 20
Factor X → blood coagulation, blood coagulation, extrinsic pathway, calcium ion binding, endoplasmic reticulum lumen, endoplasmic reticulum to Golgi vesicle-mediated transport, extracellular region, extracellular space, Golgi lumen, hemostasis, hydrolase activity, intrinsic component of external side of plasma membrane, peptidase activity, phospholipid binding, plasma membrane, positive regulation of cell migration, positive regulation of protein kinase B signaling, protein binding, proteolysis, serine-type endopeptidase activity, serine-type peptidase activity
RNA expression pattern · 20
Factor X → blood, bone marrow, canal of the cervix, ectocervix, embryo, epithelium of small intestine, fetal liver hematopoietic progenitor cell, gallbladder, gastric mucosa, granulocyte, left lobe of liver, left ovary, left uterine tube, right auricle of heart, right coronary artery, right lobe of liver, right ovary, sexually immature organism, stromal cell of endometrium, yolk sac
related to Therapeutic use · 18
Factor X → Behring, Bio Products Laboratory, CHMP, Coagadex, COMP, CSL Behring, EU, Factor, Factors II, FDA, IX, Kcentra, March, October, Proteins, There, United States, VII
related to history · 11
Factor X → American, As, At, British, Miss Audrey Prower, Morawitz, Mr Rufus Stuart, Paul Morawitz, That, Those, Thrombokinase
related to External links · 9
Factor X → April, Canadian Hemophilia Society, EMBL, European Molecular Biology Laboratory, Factor, MEROPS, S01, Summary, Xa
related to Factor Xa · 9
Factor X → Factor, Factor II, Factor IIa, Factor Xa, Factor Xa/Va, TF, The, These, Traditional
related to Use in biochemistry · 7
Factor X → After, IDGR, IEGR, Ile-Glu/Asp-Gly-Arg, Its, The, Xa
related to Role in disease · 6
Factor X → Apart, As, Deficiency, For, In, Inborn

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

factor xa coagulation thrombin enzyme prothrombin complex protein human bp gene thrombokinase activated activity pathway chr prothrombinase band chromosome 13

Factor X relationships Subject–Predicate–Object triples

TTTA extracted 175 structured relationships around Factor X. Examples in this analysis include Factor X → 3.4.21.6 → ↗ and Factor X → Aliases → F10, FX, FXA, coagulation factor X. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Factor X3.4.21.61.00infobox
Factor XAliasesF10, FX, FXA, coagulation factor X1.00infobox
Factor XAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C5M, 1EZQ, 1F0R, 1F0S, 1FAX, 1FJS, 1G2L, 1G2M, 1HCG, 1IOE, 1IQE, 1IQF, 1IQG, 1IQH, 1IQI, 1IQJ, 1IQK, 1IQL,…1.00infobox
Factor XBand13q341.00infobox
Factor XBand8 A1.1|8 5.73 cM1.00infobox
Factor XBgeeright lobe of liver1.00infobox
Factor XBgeestromal cell of endometrium1.00infobox
Factor XBgeeright auricle of heart1.00infobox
Factor XBgeecanal of the cervix1.00infobox
Factor XBgeeectocervix1.00infobox
Factor XBgeegastric mucosa1.00infobox
Factor XBgeeright ovary1.00infobox
Factor XBgeeleft ovary1.00infobox
Factor XBgeeright coronary artery1.00infobox
Factor XBgeeleft uterine tube1.00infobox
Factor XBgeeleft lobe of liver1.00infobox
Factor XBgeeyolk sac1.00infobox
Factor XBgeegallbladder1.00infobox
Factor XBgeeembryo1.00infobox
Factor XBgeefetal liver hematopoietic progenitor cell1.00infobox
Factor XBgeeepithelium of small intestine1.00infobox
Factor XBgeeblood1.00infobox
Factor XBgeesexually immature organism1.00infobox
Factor XBgeegranulocyte1.00infobox
Factor XBgeebone marrow1.00infobox
Factor XBioGPSMore reference expression data1.00infobox
Factor XChr.Chromosome 13 (human)1.00infobox
Factor XChr.Chromosome 8 (mouse)1.00infobox
Factor XDatabasesNCBI: entry; OMA: entry1.00infobox
Factor XEnd113,149,529 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Factor X bring nearby vocabulary together. In this analysis, examples include Xa, Complex and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Factor X
    • Xa
    • Complex
    • Protein
    • Deficiency
    • Prothrombinase
    • Role
    • Activated
    • May
    • Thrombin
    • Increased
    • Gene
    • Pathway
  • factor x
    • Xa
    • Complex
    • Protein
    • Deficiency
    • Prothrombinase
    • Role
    • Activated
    • May
    • Thrombin
    • Increased
    • Gene
    • Pathway
  • coagulation cascade
    • Enzyme
    • Factors
    • F10
    • Gene
    • Pathway
    • Role
    • Tissue
    • Factor
    • Xa
    • Plasma
    • Bp
    • Chr
  • factor ix
    • Xa
    • Vii
    • Factors
    • Complex
    • Protein
    • Deficiency
    • Prothrombinase
    • Pathway
    • Surface
    • Tissue
    • Role
    • Activated
  • factor viii
    • Xa
    • Complex
    • Protein
    • Deficiency
    • Prothrombinase
    • Role
    • Activated
    • May
    • Thrombin
    • Increased
    • Gene
    • Pathway
  • factor vii
    • Xa
    • Factors
    • Complex
    • Protein
    • Surface
    • Tissue
    • Deficiency
    • Prothrombinase
    • Role
    • Activated
    • May
    • Thrombin
  • tissue factor
    • Xa
    • Factors
    • Complex
    • Protein
    • Two
    • Vii
    • Deficiency
    • Prothrombinase
    • Role
    • Activity
    • Activated
    • May
  • factor xi
    • Xa
    • Complex
    • Protein
    • Deficiency
    • Prothrombinase
    • Role
    • Activated
    • May
    • Thrombin
    • Increased
    • Gene
    • Pathway

Connections between topic areas Semantic bridges

For Factor X, one of the stronger structural bridges in this analysis connects Factor X with Factor Xa. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Factor XFactor Xa · splits 50 ⟂ 28
Factor XOverview · splits 54 ⟂ 24
Factor XRole in disease · splits 70 ⟂ 8
Factor XStructure · splits 73 ⟂ 5
Factor XTherapeutic use · splits 74 ⟂ 4
Factor XGenetics · splits 75 ⟂ 3
Factor XInteractions · splits 75 ⟂ 3

Map overview Semantic statistics

Factor X

Nodes78
Edges77
Triples175
Avg. degree1.97
Density0.025641
Components1

Source & methodology

TTTA analyzes the structure around Factor X to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications & Art, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Factor X · EN edition · Analysis: TopicsToTalkAbout

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