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Dopamine agonist

A dopamine agonist is a compound that activates dopamine D2 receptors and belong to one of two different subclasses: ergoline and non-ergoline. Examples of ergoline agonists are cabergoline and bromocriptine and examples of non-ergoline agonists are pramipexole, ropinirole and rotigotine. Ergoline agonists have been linked to cartilage formation in heart…

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ATC code
N04BC
Biological target
Dopamine receptors
MeSH
D010300
Use
Parkinson's disease, hyperprolactinemia, restless legs syndrome

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Overview

Medical uses

Adverse effects

Ergoline agonists

Mechanism of action

Structure–activity relationship

Ligands

History

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Map overview Semantic statistics

Dopamine agonist

Nodes179
Edges178
Triples88
Avg. degree1.99
Density0.011173
Components1

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Dopamine agonist

Top relations

related to history · 16
Dopamine agonist → Although, Apomorphine, Around, D2-receptor, DOPA, Dopamine, In, It, L-DOPA, Levodopa, Parkinson's, Parkinsons, Since, The, They, When
related to Interactions · 14
Dopamine agonist → AUC, CYP, CYP1A2, CYP3A4, Dopamine, For, In, L-DOPA, Parkinson's, Ropinirole, Since, That, There, When
has effect · 7
Dopamine agonist → Between, D1, D2, HT, In, Other, The
related to Parkinson's disease · 6
Dopamine agonist → Dopamine, In, In Parkinson's, Parkinson's, This, With
related to Ergoline derivatives · 5
Dopamine agonist → Central, CH2CH2CH3, N-n-Propyl, Some, The
related to Hyperprolactinemia · 5
Dopamine agonist → Dopamine, It, The, Therefore, These
related to Related class of drugs: Indirect agonists · 4
Dopamine agonist → Indirect, The, There, These
is a · 2
Dopamine agonist → compound that activates dopamine D2 receptors and belong to one of two different subclasses, increased risk of developing impulse control disorders
related to Restless leg syndrome · 2
Dopamine agonist → Numerous, RLS
ATC code · 1
Dopamine agonist → N04BC

Important terminology Word statistics

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Important terminology

dopamine agonists receptors agonist bromocriptine parkinson's effects ergoline also side drugs disease used drug d2 treatment use l-dopa pramipexole ropinirole

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Dopamine agonistATC codeN04BC1.00infobox
Dopamine agonistBiological targetDopamine receptors1.00infobox
Dopamine agonistMeSHD0103001.00infobox
Dopamine agonistUseParkinson's disease, hyperprolactinemia, restless legs syndrome1.00infobox
Dopamine agonistis acompound that activates dopamine D2 receptors and belong to one of two different subclasses0.90text
Dopamine agonistis aincreased risk of developing impulse control disorders0.90text
hypotensioninstance ofwith side effects0.80text
myocardial infarctioninstance ofwith side effects0.80text
congestive heart failureinstance ofwith side effects0.80text
cardiac fibrosisinstance ofwith side effects0.80text
pericardial effusioninstance ofwith side effects0.80text
tachycardiainstance ofwith side effects0.80text

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    Min side: 3
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