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Piribedil

Piribedil is an antiparkinsonian agent and piperazine derivative which acts as a D2 and D3 receptor agonist. It also has α2-adrenergic antagonist properties.

Applications, Medical uses & Side effects

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Explore the main themes, entities and connections around Piribedil. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
International Drug Names
ATC code
N04BC08 (WHO)
Bioavailability
10% (peak at 1 hour) [citation needed]
CAS Number
3605-01-4 Y
ChEMBL
ChEMBL1371770 N

Topics to explore

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Overview

Medical uses

Side effects

Overdose

Interactions

Pharmacology

Advanced semantic analysis

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Map overview Semantic statistics

Piribedil

Nodes54
Edges53
Triples28
Avg. degree1.96
Density0.037037
Components1

How this topic connects Entity context

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Piribedil

Top relations

related to Overdose · 3
Piribedil → At, CTZ, Tablets
Legal status · 2
Piribedil → EU: Rx-only, In general: ℞ (Prescription only)
3D model (JSmol) · 1
Piribedil → Interactive image
AHFS/Drugs.com · 1
Piribedil → International Drug Names
ATC code · 1
Piribedil → N04BC08 (WHO)
Bioavailability · 1
Piribedil → 10% (peak at 1 hour) [citation needed]
CAS Number · 1
Piribedil → 3605-01-4 Y
ChEMBL · 1
Piribedil → ChEMBL1371770 N
ChemSpider · 1
Piribedil → 4684 N
CompTox Dashboard (EPA) · 1
Piribedil → DTXSID9045188

Important terminology Word statistics

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Important terminology

receptor citation needed effect antagonist d2 agonist d3 also medical side pathological elderly attention memory dizziness drug normal piperazine derivative

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Piribedil3D model (JSmol)Interactive image1.00infobox
PiribedilAHFS/Drugs.comInternational Drug Names1.00infobox
PiribedilATC codeN04BC08 (WHO)1.00infobox
PiribedilBioavailability10% (peak at 1 hour) [citation needed]1.00infobox
PiribedilCAS Number3605-01-4 Y1.00infobox
PiribedilChEMBLChEMBL1371770 N1.00infobox
PiribedilChemSpider4684 N1.00infobox
PiribedilCompTox Dashboard (EPA)DTXSID90451881.00infobox
PiribedilECHA InfoCard100.020.6951.00infobox
PiribedilElimination half-life1.7–6.9 hours [citation needed]1.00infobox
PiribedilExcretionKidney (68%) and bile duct (25%) [citation needed]1.00infobox
PiribedilFormulaC16H18N4O21.00infobox
PiribedilIUPHAR/BPS491.00infobox
PiribedilKEGGD07305 Y1.00infobox
PiribedilLegal statusEU: Rx-only1.00infobox
PiribedilLegal statusIn general: ℞ (Prescription only)1.00infobox
PiribedilMetabolismextensive liver [citation needed]1.00infobox
PiribedilMolar mass298.346 g·mol−11.00infobox
PiribedilProtein binding70–80% [citation needed]1.00infobox
PiribedilPubChem CID48501.00infobox
PiribedilRoutes of administrationBy mouth1.00infobox
PiribedilTrade namesPronoran, Trivastal Retard, Trastal, Trivastan, Clarium, others1.00infobox
PiribedilUNIIDO22K1PRDJ1.00infobox
Piribedilis aantiparkinsonian agent and piperazine derivative which acts as a D2 and D3 receptor agonist0.90text

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