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Lergotrile: Measurement & Overview

Lergotrile (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name; developmental code name LY-79907) is an ergoline derivative which acts as a dopamine receptor agonist. It was developed for the treatment of Parkinson's disease, but failed in clinical trials due to liver toxicity.

Language: English [EN]
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Lergotrile topic overview

The analysis highlights Measurement and Overview as prominent areas in the source structure around Lergotrile.

Related topics
13
Source areas
1
Connected nodes
14
Extracted relationships
12
Concept neighborhoods
13
Bridge connections
14

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 13 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
CAS Number
36945-03-6 Y
ChEMBL
ChEMBL80937
ChemSpider
5293644
CompTox Dashboard (EPA)
DTXSID701043282
Formula
C17H18ClN3

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Lergotrile connects Entity context

The extracted context around Lergotrile shows recurring relationship patterns in the source. For example, Lergotrile → Interactive image Another extracted example is Lergotrile → 36945-03-6 Y. Use these groups to spot repeated connection types before inspecting the individual relationships.

Lergotrile

Top relations

3D model (JSmol) · 1
Lergotrile → Interactive image
CAS Number · 1
Lergotrile → 36945-03-6 Y
ChEMBL · 1
Lergotrile → ChEMBL80937
ChemSpider · 1
Lergotrile → 5293644
CompTox Dashboard (EPA) · 1
Lergotrile → DTXSID701043282
Formula · 1
Lergotrile → C17H18ClN3
KEGG · 1
Lergotrile → D04693
Molar mass · 1
Lergotrile → 299.80 g·mol−1
Other names · 1
Lergotrile → LY-79907; 2-Chloro-6-methylergoline-8β-acetonitrile
PubChem CID · 1
Lergotrile → 6918447

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

dopamine receptor agonist name ly-79907 ergoline derivative hydroxylated metabolite 13-hydroxylergotrile potent inntooltip international nonproprietary usantooltip united states adopted developmental code

Lergotrile relationships Subject–Predicate–Object triples

TTTA extracted 12 structured relationships around Lergotrile. Examples in this analysis include Lergotrile → 3D model (JSmol) → Interactive image and Lergotrile → CAS Number → 36945-03-6 Y. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Lergotrile3D model (JSmol)Interactive image1.00infobox
LergotrileCAS Number36945-03-6 Y1.00infobox
LergotrileChEMBLChEMBL809371.00infobox
LergotrileChemSpider52936441.00infobox
LergotrileCompTox Dashboard (EPA)DTXSID7010432821.00infobox
LergotrileFormulaC17H18ClN31.00infobox
LergotrileKEGGD046931.00infobox
LergotrileMolar mass299.80 g·mol−11.00infobox
LergotrileOther namesLY-79907; 2-Chloro-6-methylergoline-8β-acetonitrile1.00infobox
LergotrilePubChem CID69184471.00infobox
LergotrileUNIIO68JXU1W091.00infobox
Lergotrilesee alsoSubstituted0.60section

Related concept clusters Concept neighborhoods

The concept neighborhoods around Lergotrile bring nearby vocabulary together. In this analysis, examples include Agonist, Dopamine and Ergoline. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Lergotrile
    • Agonist
    • Dopamine
    • Ergoline
    • Ly-79907
    • Name
    • Receptor
    • 100-fold
    • 13-hydroxylergotrile
    • Acts
    • Adopted
    • Code
    • Derivative
  • lergotrile
    • Agonist
    • Dopamine
    • Ergoline
    • Ly-79907
    • Name
    • Receptor
    • 100-fold
    • 13-hydroxylergotrile
    • Acts
    • Adopted
    • Code
    • Derivative
  • dopamine receptor agonist
    • Agonist
    • Dopamine
    • Receptor
    • Lergotrile
    • 100-fold
    • 13-hydroxylergotrile
    • Code
    • Derivative
    • Developmental
    • Drug's
    • Hydroxylated
    • Inntooltip
  • ergoline
    • Ly-79907
    • Name
    • Lergotrile
    • Acts
    • Also
    • Derivative
    • Inntooltip
    • International
    • Nonproprietary
    • References
    • See
    • States
  • derivative
    • Acts
    • Developmental
    • Inntooltip
    • International
    • Nonproprietary
    • States
    • United
    • Usantooltip
    • Agonist
    • Dopamine
    • Ergoline
    • Ly-79907
  • clinical trials
    • Clinical
    • Developed
    • Disease
    • Due
    • Failed
    • Liver
    • Parkinson's
    • Toxicity
    • Treatment
    • Trials
  • 13-hydroxylergotrile
    • 100-fold
    • Drug's
    • Hydroxylated
    • Metabolite
    • Potent
    • Vitro
    • Agonist
    • Dopamine
    • Receptor
    • Lergotrile
  • in vitro
    • 100-fold
    • 13-hydroxylergotrile
    • Drug's
    • Hydroxylated
    • Metabolite
    • Potent
    • Agonist
    • Dopamine
    • Receptor
    • Lergotrile

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the Lergotrile map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

Lergotrile

Nodes15
Edges14
Triples12
Avg. degree1.87
Density0.133333
Components1

Source & methodology

TTTA analyzes the structure around Lergotrile to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Lergotrile · EN edition · Analysis: TopicsToTalkAbout

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