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Cabergoline: History, Applications & Research

Cabergoline, sold under the brand name Dostinex among others, is a dopaminergic medication used in the treatment of high prolactin levels, prolactinomas, Parkinson's disease, and for other indications. It is taken by mouth.

Language: English [EN]
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Cabergoline topic overview

The analysis highlights History, Applications and Research as prominent areas in the source structure around Cabergoline.

Related topics
143
Source areas
8
Connected nodes
151
Extracted relationships
123
Concept neighborhoods
28
Bridge connections
151

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Pharmacology · 36 topics
Side effects · 36 topics
Medical uses · 33 topics
Contraindications · 14 topics
Overview · 11 topics
Interactions · 6 topics
History · 5 topics
Research · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
G02CB03 (WHO) N04BC06 (WHO)
Bioavailability
50–80%
CAS Number
81409-90-7 Y
ChEBI
CHEBI:3286 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Contraindications

Side effects

Interactions

Pharmacology

History

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Cabergoline connects Entity context

The extracted context around Cabergoline shows recurring relationship patterns in the source. For example, Cabergoline → Although, D1, D2, D3, D4, Ergot, HT1A, HT2A, HT2B, HT2C, HT7, In-vitro Another extracted example is Cabergoline → Additionally, Also, GDNF, It, IVF, OHSS, One, Oral, SSRI, Vaginal. Use these groups to spot repeated connection types before inspecting the individual relationships.

Cabergoline

Top relations

related to Pharmacodynamics · 12
Cabergoline → Although, D1, D2, D3, D4, Ergot, HT1A, HT2A, HT2B, HT2C, HT7, In-vitro
related to Off-label · 10
Cabergoline → Additionally, Also, GDNF, It, IVF, OHSS, One, Oral, SSRI, Vaginal
related to Valvular heart disease · 10
Cabergoline → As, FDA, In, January, March, Medicine, New England Journal, Parkinson's Disease, Since, The
related to Medical uses · 9
Cabergoline → Adjunctive, Combination, Growth, In, Lactation, Medical, Monotherapy, Parkinson's, Treatment
related to Pharmacokinetics · 9
Cabergoline → All, Average, Following, GI, Human, In, Ingestion, Parkinson's, The
related to history · 8
Cabergoline → Farmitalia-Carlo Erba, Italian, Milan, Neuroscience, Pfizer, Pharmacia, Society, The
related to Pregnancy and lactation · 8
Cabergoline → Dostinex, However, In, It, Lactation, Pregnancy, Relatively, Since
related to Contraindications · 6
Cabergoline → Cautions, Contraindications, CYP450, Hypersensitivity, Raynaud's, Severely
related to Brand names · 5
Cabergoline → Brand, Cabaser, Dostinex, Galastop, Kelactin
has effect · 4
Cabergoline → Much, Parkinson's, Side, The

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

effects side disease treatment patients pregnancy hyperprolactinemia used ergot also parkinson's use may lactation dostinex derivatives dopamine agonist frequent drug

Cabergoline relationships Subject–Predicate–Object triples

TTTA extracted 123 structured relationships around Cabergoline. Examples in this analysis include Cabergoline → 3D model (JSmol) → Interactive image and Cabergoline → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Cabergoline3D model (JSmol)Interactive image1.00infobox
CabergolineAHFS/Drugs.comMonograph1.00infobox
CabergolineATC codeG02CB03 (WHO) N04BC06 (WHO)1.00infobox
CabergolineBioavailability50–80%1.00infobox
CabergolineCAS Number81409-90-7 Y1.00infobox
CabergolineChEBICHEBI:3286 Y1.00infobox
CabergolineChEMBLChEMBL1201087 N1.00infobox
CabergolineChemSpider49452 Y1.00infobox
CabergolineCompTox Dashboard (EPA)DTXSID60227191.00infobox
CabergolineDrugBankDB00248 Y1.00infobox
CabergolineECHA InfoCard100.155.3801.00infobox
CabergolineElimination half-life63–69 hours (estimated)1.00infobox
CabergolineExcretionUrine (22%), feces (60%)1.00infobox
CabergolineFormulaC26H37N5O21.00infobox
CabergolineIUPHAR/BPS371.00infobox
CabergolineKEGGD00987 Y1.00infobox
CabergolineLegal statusAU: S4 (Prescription only)1.00infobox
CabergolineLegal statusUS: ℞-only1.00infobox
CabergolineLicense dataUS DailyMed: Cabergoline1.00infobox
CabergolineMetabolismLiver, predominately via hydrolysis of the acylurea bond or the urea moiety1.00infobox
CabergolineMolar mass451.615 g·mol−11.00infobox
CabergolineOther namesN-[3-(Dimethylamino)propyl]-N-(ethylcarbamoyl)-6-(prop-2-en-1-yl)ergoline-8β-carboxamide1.00infobox
CabergolineProtein bindingModerately bound (40–42%); concentration-independent1.00infobox
CabergolinePubChem CID547461.00infobox
CabergolineRoutes of administrationOral1.00infobox
CabergolineTrade namesDostinex, others1.00infobox
CabergolineUNIILL60K9J05T1.00infobox
Cabergolineis aergot derivative and a potent dopamine D2 receptor agonist.Cabergoline was patented in 1980 and approved for medical use in 19930.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Cabergoline bring nearby vocabulary together. In this analysis, examples include Disease, Treatment and Effects. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Cabergoline
    • Disease
    • Treatment
    • Effects
    • Dostinex
    • Levels
    • Receptor
    • Hyperprolactinemia
    • Parkinson's
    • Side
    • Pregnancy
    • Used
    • Patients
  • cabergoline
    • Disease
    • Treatment
    • Effects
    • Dostinex
    • Levels
    • Receptor
    • Hyperprolactinemia
    • Parkinson's
    • Side
    • Pregnancy
    • Used
    • Patients
  • parkinson's disease
    • Parkinson's
    • Hyperprolactinemia
    • Treatment
    • Prolactinomas
    • Pituitary
    • Hours
    • Others
    • Used
    • Side
    • Effects
    • Dostinex
    • Levels
  • side effects
    • Side
    • Treatment
    • Patients
    • Used
    • Dose
    • Percent
    • Hyperprolactinemia
    • Parkinson's
    • Pregnancy
    • One
    • Prolactinomas
    • Drugs
  • cardiovascular disease
    • Parkinson's
    • Hyperprolactinemia
    • Treatment
    • Pituitary
    • Others
    • Prolactinomas
    • Hours
    • Dostinex
    • Levels
    • One
    • Side
    • Effects
  • raynaud's disease
    • Parkinson's
    • Hyperprolactinemia
    • Treatment
    • Pituitary
    • Others
    • Prolactinomas
    • Hours
    • Dostinex
    • Levels
    • One
    • Side
    • Effects
  • valvular heart disease
    • Parkinson's
    • Hyperprolactinemia
    • Treatment
    • Pituitary
    • Others
    • Prolactinomas
    • Hours
    • Dostinex
    • Levels
    • One
    • Side
    • Effects
  • bioavailability
    • Oral
    • Medical
    • Brand
    • Others
    • Prolactinomas
    • Drugs
    • Hours
    • Lactation
    • Liver
    • Pituitary
    • Rats
    • Dostinex

Connections between topic areas Semantic bridges

For Cabergoline, one of the stronger structural bridges in this analysis connects Cabergoline with Side effects. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CabergolineSide effects · splits 115 ⟂ 37
CabergolinePharmacology · splits 115 ⟂ 37
CabergolineMedical uses · splits 118 ⟂ 34
CabergolineContraindications · splits 137 ⟂ 15
CabergolineOverview · splits 140 ⟂ 12
CabergolineInteractions · splits 145 ⟂ 7
CabergolineHistory · splits 146 ⟂ 6
CabergolineResearch · splits 149 ⟂ 3

Map overview Semantic statistics

Cabergoline

Nodes152
Edges151
Triples123
Avg. degree1.99
Density0.013158
Components1

Source & methodology

TTTA analyzes the structure around Cabergoline to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Cabergoline · EN edition · Analysis: TopicsToTalkAbout

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