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Alpha-synuclein (aSyn) is a protein that in humans is encoded by the SNCA gene. It is a neuronal protein involved in the regulation of synaptic vesicle trafficking and the release of neurotransmitters.
Tissue expression, Structure & Clinical significance
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protein aggregation disease synuclein human gene neurons also snca lipid structure shown cells brain synaptic amyloid membrane parkinson's synucleinopathies vesicles
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Alpha-synuclein | Aliases | SNCA, NACP, PARK1, PARK4, PD1, synuclein alpha | 1.00 | infobox |
| Alpha-synuclein | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1XQ8, 2JN5, 2KKW, 2M55, 2X6M, 3Q25, 3Q26, 3Q27, 3Q28, 3Q29, 4BXL, 4R0U, 4R0W, 4RIK, 4RIL, 4ZNN, 5CRW, 2N0A | 1.00 | infobox |
| Alpha-synuclein | Band | 4q22.1 | 1.00 | infobox |
| Alpha-synuclein | Band | 6 B3|6 29.15 cM | 1.00 | infobox |
| Alpha-synuclein | Bgee | trabecular bone | 1.00 | infobox |
| Alpha-synuclein | Bgee | orbitofrontal cortex | 1.00 | infobox |
| Alpha-synuclein | Bgee | pons | 1.00 | infobox |
| Alpha-synuclein | Bgee | Brodmann area 46 | 1.00 | infobox |
| Alpha-synuclein | Bgee | endothelial cell | 1.00 | infobox |
| Alpha-synuclein | Bgee | Brodmann area 23 | 1.00 | infobox |
| Alpha-synuclein | Bgee | tendon of biceps brachii | 1.00 | infobox |
| Alpha-synuclein | Bgee | postcentral gyrus | 1.00 | infobox |
| Alpha-synuclein | Bgee | middle temporal gyrus | 1.00 | infobox |
| Alpha-synuclein | Bgee | monocyte | 1.00 | infobox |
| Alpha-synuclein | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| Alpha-synuclein | Bgee | subiculum | 1.00 | infobox |
| Alpha-synuclein | Bgee | fetal liver hematopoietic progenitor cell | 1.00 | infobox |
| Alpha-synuclein | Bgee | nucleus accumbens | 1.00 | infobox |
| Alpha-synuclein | Bgee | dorsal striatum | 1.00 | infobox |
| Alpha-synuclein | Bgee | barrel cortex | 1.00 | infobox |
| Alpha-synuclein | Bgee | anterior amygdaloid area | 1.00 | infobox |
| Alpha-synuclein | Bgee | ventral tegmental area | 1.00 | infobox |
| Alpha-synuclein | Bgee | hippocampus proper | 1.00 | infobox |
| Alpha-synuclein | Bgee | habenula | 1.00 | infobox |
| Alpha-synuclein | BioGPS | More reference expression data | 1.00 | infobox |
| Alpha-synuclein | Chr. | Chromosome 4 (human) | 1.00 | infobox |
| Alpha-synuclein | Chr. | Chromosome 6 (mouse) | 1.00 | infobox |
| Alpha-synuclein | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Alpha-synuclein | End | 89,838,315 bp | 1.00 | infobox |
| Alpha-synuclein | End | 60,806,839 bp | 1.00 | infobox |
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