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Synucleinopathies are neurodegenerative diseases characterised by the abnormal accumulation of aggregates of alpha-synuclein protein in neurons, nerve fibres or glial cells. The synucleinopathies include Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). Other rare disorders, such as various neuroaxonal…
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alpha-synuclein synucleinopathies dysfunction symptoms dlb also lewy bodies pd may include msa sleep disease protein rare hallucinations parkinson's dementia multiple
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Synucleinopathy | Causes | Unknown | 1.00 | infobox |
| Synucleinopathy | Duration | Long term | 1.00 | infobox |
| Synucleinopathy | Other names | α-synucleinopathies | 1.00 | infobox |
| Synucleinopathy | Specialty | Neurology | 1.00 | infobox |
| Synucleinopathy | Symptoms | Autonomic dysfunction, motor impairments, cognitive and sleep issues, parkinsonism, memory loss, hallucinations | 1.00 | infobox |
| Synucleinopathy | Types | Parkinson's disease, dementia with Lewy bodies, multiple system atrophy | 1.00 | infobox |
| delayed gastric emptying or lower gastrointestinal dysfunction | instance of | Symptoms include upper gastrointestinal tract dysfunction | 0.80 | text |
| such as constipation | instance of | Symptoms include upper gastrointestinal tract dysfunction | 0.80 | text |
| prolonged stool transit time.Urinary retention | instance of | Symptoms include upper gastrointestinal tract dysfunction | 0.80 | text |
| waking at night to urinate | instance of | Symptoms include upper gastrointestinal tract dysfunction | 0.80 | text |
| increased urinary frequency | instance of | Symptoms include upper gastrointestinal tract dysfunction | 0.80 | text |
| urgency | instance of | Symptoms include upper gastrointestinal tract dysfunction | 0.80 | text |
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