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Synucleinopathy

Synucleinopathies are neurodegenerative diseases characterised by the abnormal accumulation of aggregates of alpha-synuclein protein in neurons, nerve fibres or glial cells. The synucleinopathies include Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). Other rare disorders, such as various neuroaxonal…

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Causes
Unknown
Duration
Long term
Other names
α-synucleinopathies
Specialty
Neurology
Symptoms
Autonomic dysfunction, motor impairments, cognitive and sleep issues, parkinsonism, memory loss, hallucinations
Types
Parkinson's disease, dementia with Lewy bodies, multiple system atrophy

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Synucleinopathy

Nodes53
Edges52
Triples19
Avg. degree1.96
Density0.037736
Components1

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Synucleinopathy

Top relations

Causes · 1
Synucleinopathy → Unknown
Duration · 1
Synucleinopathy → Long term
Other names · 1
Synucleinopathy → α-synucleinopathies
Specialty · 1
Synucleinopathy → Neurology
Symptoms · 1
Synucleinopathy → Autonomic dysfunction, motor impairments, cognitive and sleep issues, parkinsonism, memory loss, hallucinations
Types · 1
Synucleinopathy → Parkinson's disease, dementia with Lewy bodies, multiple system atrophy

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Important terminology

alpha-synuclein synucleinopathies dysfunction symptoms dlb also lewy bodies pd may include msa sleep disease protein rare hallucinations parkinson's dementia multiple

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SynucleinopathyCausesUnknown1.00infobox
SynucleinopathyDurationLong term1.00infobox
SynucleinopathyOther namesα-synucleinopathies1.00infobox
SynucleinopathySpecialtyNeurology1.00infobox
SynucleinopathySymptomsAutonomic dysfunction, motor impairments, cognitive and sleep issues, parkinsonism, memory loss, hallucinations1.00infobox
SynucleinopathyTypesParkinson's disease, dementia with Lewy bodies, multiple system atrophy1.00infobox
delayed gastric emptying or lower gastrointestinal dysfunctioninstance ofSymptoms include upper gastrointestinal tract dysfunction0.80text
such as constipationinstance ofSymptoms include upper gastrointestinal tract dysfunction0.80text
prolonged stool transit time.Urinary retentioninstance ofSymptoms include upper gastrointestinal tract dysfunction0.80text
waking at night to urinateinstance ofSymptoms include upper gastrointestinal tract dysfunction0.80text
increased urinary frequencyinstance ofSymptoms include upper gastrointestinal tract dysfunction0.80text
urgencyinstance ofSymptoms include upper gastrointestinal tract dysfunction0.80text

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