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Bleomycin: History, Applications & Research

Bleomycin is a medication primarily used to treat cancer. This includes Hodgkin's lymphoma, non-Hodgkin's lymphoma, testicular cancer, ovarian cancer, and cervical cancer among others. Typically used with other cancer medications, it can be given intravenously, by injection into a muscle or under the skin. It may also be administered inside the chest to…

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Bleomycin topic overview

The analysis highlights History, Applications and Research as prominent areas in the source structure around Bleomycin.

Related topics
44
Source areas
6
Connected nodes
50
Extracted relationships
71
Concept neighborhoods
21
Bridge connections
50

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 20 topics
Side effects · 12 topics
History · 4 topics
Mechanism of action · 4 topics
Medical uses · 3 topics
Research · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
L01DC01 (WHO)
Bioavailability
100% and 70% following intramuscular and subcutaneous administrations, respectively, and 45% following both intraperitoneal and intrapleural administrations
CAS Number
11056-06-7 Y · sulfate: 9041-93-4 Y
ChEBI
CHEBI:22907 N

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Side effects

Mechanism of action

History

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Bleomycin connects Entity context

The extracted context around Bleomycin shows recurring relationship patterns in the source. For example, Bleomycin → Blenoxane, Bristol Laboratories, Bristol-Myers Squibb, FDA, Hamao Umezawa, In, It, Japan, Japanese, July, Nippon Kayaku, Streptomyces, The, Umezawa, US Another extracted example is Bleomycin → Any, Due, IL-18, IL-1beta, It, Raynaud's, The. Use these groups to spot repeated connection types before inspecting the individual relationships.

Bleomycin

Top relations

related to history · 15
Bleomycin → Blenoxane, Bristol Laboratories, Bristol-Myers Squibb, FDA, Hamao Umezawa, In, It, Japan, Japanese, July, Nippon Kayaku, Streptomyces, The, Umezawa, US
has effect · 7
Bleomycin → Any, Due, IL-18, IL-1beta, It, Raynaud's, The
related to Mechanism of action · 5
Bleomycin → An, Criegee-type, DNA, Some, The
Legal status · 4
Bleomycin → AU: S4 (Prescription only), EU: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Cancer · 3
Bleomycin → Hodgkin's, It, This
CAS Number · 2
Bleomycin → 11056-06-7 Y, sulfate: 9041-93-4 Y
KEGG · 2
Bleomycin → D07535 N, sulfate: C15773 N
UNII · 2
Bleomycin → 40S1VHN69B, sulfate: 7DP3NTV15T Y
related to Biosynthesis · 2
Bleomycin → Biosynthesis, DNA
see also · 2
Bleomycin → Bleomycin A5, Flagellate

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cancer may dna used also primarily treat skin chest side effects pulmonary fibrosis oxygen pleural effusion due lung medication cause

Bleomycin relationships Subject–Predicate–Object triples

TTTA extracted 71 structured relationships around Bleomycin. Examples in this analysis include Bleomycin → 3D model (JSmol) → Interactive image and Bleomycin → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Bleomycin3D model (JSmol)Interactive image1.00infobox
BleomycinAHFS/Drugs.comMonograph1.00infobox
BleomycinATC codeL01DC01 (WHO)1.00infobox
BleomycinBioavailability100% and 70% following intramuscular and subcutaneous administrations, respectively, and 45% following both intraperitoneal and intrapleural administrations1.00infobox
BleomycinCAS Number11056-06-7 Y1.00infobox
BleomycinCAS Numbersulfate: 9041-93-4 Y1.00infobox
BleomycinChEBICHEBI:22907 N1.00infobox
BleomycinChEMBLChEMBL403664 N1.00infobox
BleomycinChemSpider4574226 N1.00infobox
BleomycinCompTox Dashboard (EPA)DTXSID10308621.00infobox
BleomycinDrug classGlycopeptide antibiotic1.00infobox
BleomycinDrugBankDB00290 N1.00infobox
BleomycinElimination half-lifetwo hours1.00infobox
BleomycinExcretionKidney (60–70%)1.00infobox
BleomycinFormulaC55H84N17O21S31.00infobox
BleomycinKEGGD07535 N1.00infobox
BleomycinKEGGsulfate: C15773 N1.00infobox
BleomycinLegal statusAU: S4 (Prescription only)1.00infobox
BleomycinLegal statusUK: POM (Prescription only)1.00infobox
BleomycinLegal statusUS: ℞-only1.00infobox
BleomycinLegal statusEU: Rx-only1.00infobox
BleomycinLicense dataUS DailyMed: Bleomycin1.00infobox
BleomycinMedlinePlusa6821251.00infobox
BleomycinMolar mass1415.56 g·mol−11.00infobox
BleomycinPregnancy categoryAU: D1.00infobox
BleomycinPubChem CID54607691.00infobox
BleomycinRoutes of administrationintravenous, intramuscular, subcutaneous, intrapleural1.00infobox
BleomycinTrade namesBlenoxane1.00infobox
BleomycinUNII40S1VHN69B1.00infobox
BleomycinUNIIsulfate: 7DP3NTV15T Y1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Bleomycin bring nearby vocabulary together. In this analysis, examples include Dna, Fibrosis and Oxygen. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Bleomycin
    • Dna
    • Fibrosis
    • Oxygen
    • Pulmonary
    • Used
    • Cleavage
    • Mechanism
    • Strand
    • Primarily
    • Also
    • Pregnancy
    • Drug
  • bleomycin
    • Dna
    • Fibrosis
    • Oxygen
    • Pulmonary
    • Used
    • Cleavage
    • Mechanism
    • Strand
    • Primarily
    • Also
    • Pregnancy
    • Drug
  • cancer
    • Also
    • Used
    • Hodgkin's
    • Includes
    • Inside
    • Non-hodgkin's
    • Ovarian
    • Testicular
    • Chest
    • Due
    • Effusion
    • Pleural
  • testicular cancer
    • Hodgkin's
    • Includes
    • Non-hodgkin's
    • Ovarian
    • Also
    • Used
    • Cancer
    • Inside
    • Testicular
    • Chest
    • Due
    • Effusion
  • ovarian cancer
    • Testicular
    • Also
    • Used
    • Hodgkin's
    • Includes
    • Inside
    • Non-hodgkin's
    • Ovarian
    • Chest
    • Due
    • Effusion
    • Pleural
  • cervical cancer
    • Also
    • Used
    • Hodgkin's
    • Includes
    • Inside
    • Non-hodgkin's
    • Ovarian
    • Testicular
    • Chest
    • Due
    • Effusion
    • Pleural
  • cancer medications
    • Also
    • Used
    • Hodgkin's
    • Includes
    • Inside
    • Non-hodgkin's
    • Ovarian
    • Testicular
    • Chest
    • Due
    • Effusion
    • Pleural
  • side effects
    • Side
    • Fever
    • Check
    • Pregnancy
    • Drug
    • Mechanism
    • Treat
    • Us
    • Used

Connections between topic areas Semantic bridges

For Bleomycin, one of the stronger structural bridges in this analysis connects Bleomycin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Bleomycin — Overview · splits 30 ⟂ 21
Bleomycin — Side effects · splits 38 ⟂ 13
Bleomycin — Mechanism of action · splits 46 ⟂ 5
Bleomycin — History · splits 46 ⟂ 5
Bleomycin — Medical uses · splits 47 ⟂ 4

Map overview Semantic statistics

Bleomycin

Nodes51
Edges50
Triples71
Avg. degree1.96
Density0.039216
Components1

Source & methodology

TTTA analyzes the structure around Bleomycin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Bleomycin · EN edition · Analysis: TopicsToTalkAbout

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