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SOX17: Structure, Function & Overview

SRY-box 17 is a protein that in humans is encoded by the SOX17 gene.

Language: English [EN]
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SOX17 topic overview

The analysis highlights Structure, Function and Overview as prominent areas in the source structure around SOX17.

Related topics
6
Source areas
3
Connected nodes
9
Extracted relationships
154
Concept neighborhoods
7
Bridge connections
9

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 2 topics
Overview · 2 topics
Structure · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SOX17, VUR3, SRY-box 17, SRY-box transcription factor 17
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YUL, 4A3N
Band
8q11.23 · 1 A1|1 1.65 cM
Bgee
endothelial cell · pericardium · endometrium · right uterine tube · vena cava
BioGPS
n/a
Chr.
Chromosome 8 (human) · Chromosome 1 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How SOX17 connects Entity context

The extracted context around SOX17 shows recurring relationship patterns in the source. For example, SOX17 → angiogenesis, beta-catenin binding, canonical Wnt signaling pathway, cardiac cell fate determination, cardiogenic plate morphogenesis, cell differentiation, cell migration involved in gastrulation, cellular response to leukemia inhibitory factor, common bile duct development, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic foregut morphogenesis, embryonic heart tube development, embryonic heart tube morphogenesis, embryonic organ development, endocardial cell differentiation, endocardium formation, endoderm development Another extracted example is SOX17 → carotid body, endometrium, endothelial cell, external carotid artery, gastrula, gonad, internal carotid artery, left lung lobe, left uterine tube, muscle of thigh, pericardium, primitive streak, right lung, right lung lobe, right uterine tube, subcutaneous adipose tissue, substantia nigra, tibial nerve, uterus, vena cava. Use these groups to spot repeated connection types before inspecting the individual relationships.

SOX17

Top relations

Gene ontology · 69
SOX17 → angiogenesis, beta-catenin binding, canonical Wnt signaling pathway, cardiac cell fate determination, cardiogenic plate morphogenesis, cell differentiation, cell migration involved in gastrulation, cellular response to leukemia inhibitory factor, common bile duct development, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic foregut morphogenesis, embryonic heart tube development, embryonic heart tube morphogenesis, embryonic organ development, endocardial cell differentiation, endocardium formation, endoderm development
Bgee · 20
SOX17 → carotid body, endometrium, endothelial cell, external carotid artery, gastrula, gonad, internal carotid artery, left lung lobe, left uterine tube, muscle of thigh, pericardium, primitive streak, right lung, right lung lobe, right uterine tube, subcutaneous adipose tissue, substantia nigra, tibial nerve, uterus, vena cava
RNA expression pattern · 20
SOX17 → carotid body, endometrium, endothelial cell, external carotid artery, gastrula, gonad, internal carotid artery, left lung lobe, left uterine tube, muscle of thigh, pericardium, primitive streak, right lung, right lung lobe, right uterine tube, subcutaneous adipose tissue, substantia nigra, tibial nerve, uterus, vena cava
related to Function · 13
SOX17 → Activin, Besides, CTCF-boundary, Especially, G1, In Xenopus, SMAD2/3, Tcf, TGF, The, WNT, Wnt/β-catenin, Wnt3a
related to Structure · 9
SOX17 → Approximately, CTCF, DMR, DNA, PCGs, The DMR, The SOX17, TIG, TIGs
Band · 2
SOX17 → 1 A1|1 1.65 cM, 8q11.23
Chr. · 2
SOX17 → Chromosome 1 (mouse), Chromosome 8 (human)
End · 2
SOX17 → 4,567,577 bp, 54,460,892 bp
Aliases · 1
SOX17 → SOX17, VUR3, SRY-box 17, SRY-box transcription factor 17
Available structures · 1
SOX17 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YUL, 4A3N

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp chr human band chromosome protein transcription endodermal location mouse expression cell wnt sry-box 17 function definitive encoded factor

SOX17 relationships Subject–Predicate–Object triples

TTTA extracted 154 structured relationships around SOX17. Examples in this analysis include SOX17 → Aliases → SOX17, VUR3, SRY-box 17, SRY-box transcription factor 17 and SOX17 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YUL, 4A3N. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SOX17AliasesSOX17, VUR3, SRY-box 17, SRY-box transcription factor 171.00infobox
SOX17Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YUL, 4A3N1.00infobox
SOX17Band8q11.231.00infobox
SOX17Band1 A1|1 1.65 cM1.00infobox
SOX17Bgeeendothelial cell1.00infobox
SOX17Bgeepericardium1.00infobox
SOX17Bgeeendometrium1.00infobox
SOX17Bgeeright uterine tube1.00infobox
SOX17Bgeevena cava1.00infobox
SOX17Bgeegonad1.00infobox
SOX17Bgeeleft uterine tube1.00infobox
SOX17Bgeetibial nerve1.00infobox
SOX17Bgeesubcutaneous adipose tissue1.00infobox
SOX17Bgeemuscle of thigh1.00infobox
SOX17Bgeeleft lung lobe1.00infobox
SOX17Bgeegastrula1.00infobox
SOX17Bgeeexternal carotid artery1.00infobox
SOX17Bgeeprimitive streak1.00infobox
SOX17Bgeeinternal carotid artery1.00infobox
SOX17Bgeeright lung1.00infobox
SOX17Bgeeright lung lobe1.00infobox
SOX17Bgeeuterus1.00infobox
SOX17Bgeecarotid body1.00infobox
SOX17Bgeesubstantia nigra1.00infobox
SOX17BioGPSn/a1.00infobox
SOX17Chr.Chromosome 8 (human)1.00infobox
SOX17Chr.Chromosome 1 (mouse)1.00infobox
SOX17DatabasesNCBI: entry; OMA: entry1.00infobox
SOX17End54,460,892 bp1.00infobox
SOX17End4,567,577 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around SOX17 bring nearby vocabulary together. In this analysis, examples include Gene, Definitive and Expression. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • SOX17
    • Gene
    • Definitive
    • Expression
    • Transcription
    • Endodermal
    • Development
    • Distal
    • Dna
    • Embryonic
    • Endoderm
    • Enhancer
    • External
  • sox17
    • Gene
    • Definitive
    • Expression
    • Transcription
    • Endodermal
    • Development
    • Distal
    • Dna
    • Embryonic
    • Endoderm
    • Enhancer
    • External
  • protein
    • Encoded
    • Wnt
    • Gene
    • A1
    • Development
    • Distal
    • Dna
    • Embryonic
    • End
    • Endoderm
    • Enhancer
    • External
  • gene
    • Location
    • Chromosome
    • Human
    • Sox17
    • Bp
    • Chr
    • A1
    • Dna
    • End
    • External
    • Factor
    • Function
  • canonical wnt signaling
    • Transcription
    • Protein
    • A1
    • Development
    • Distal
    • Dna
    • Embryonic
    • Encoded
    • End
    • Endoderm
    • Enhancer
    • External
  • function
    • External
    • Factor
    • Search
    • Location
    • Transcription
    • Chromosome
    • Human
    • Bp
    • Chr
    • A1
    • Development
    • Distal
  • endoderm
    • Expression
    • Embryonic
    • Enhancer
    • External
    • Factor
    • Function
    • Mouse
    • Regulation
    • Search
    • Tissue
    • Definitive
    • Location

Connections between topic areas Semantic bridges

For SOX17, one of the stronger structural bridges in this analysis connects SOX17 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SOX17Overview · splits 7 ⟂ 3
SOX17Structure · splits 7 ⟂ 3
SOX17Function · splits 7 ⟂ 3

Map overview Semantic statistics

SOX17

Nodes10
Edges9
Triples154
Avg. degree1.8
Density0.2
Components1

Source & methodology

TTTA analyzes the structure around SOX17 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Structure, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SOX17 · EN edition · Analysis: TopicsToTalkAbout

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