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Fibroblast growth factor receptor substrate 2 is a protein that in humans is encoded by the FRS2 gene.
The analysis highlights Interactions and Overview as prominent areas in the source structure around FRS2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around FRS2 shows recurring relationship patterns in the source. For example, FRS2 → 1-phosphatidylinositol-3-kinase activity, anterior/posterior axis specification, embryo, axon guidance, cell-cell junction, cytoplasm, cytosol, endomembrane system, endosome, fibroblast growth factor receptor binding, fibroblast growth factor receptor signaling pathway, forebrain development, G protein-coupled receptor signaling pathway, gastrulation with mouth forming second, integral component of plasma membrane, lens development in camera-type eye, lens fiber cell development, lens placode formation involved in camera-type eye formation, MAPK cascade, membrane, negative regulation of cardiac muscle cell differentiation Another extracted example is FRS2 → Achilles tendon, C1 segment, endothelial cell, epithelium of colon, ganglionic eminence, gonad, islet of Langerhans, stromal cell of endometrium, testicle, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
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TTTA extracted 80 structured relationships around FRS2. Examples in this analysis include FRS2 → Aliases → FRS2, FRS2A, FRS2alpha, SNT, SNT-1, SNT1, FRS1A, fibroblast growth factor receptor substrate 2 and FRS2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1XR0, 2MFQ. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| FRS2 | Aliases | FRS2, FRS2A, FRS2alpha, SNT, SNT-1, SNT1, FRS1A, fibroblast growth factor receptor substrate 2 | 1.00 | infobox |
| FRS2 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1XR0, 2MFQ | 1.00 | infobox |
| FRS2 | Band | 12q15 | 1.00 | infobox |
| FRS2 | Bgee | Achilles tendon | 1.00 | infobox |
| FRS2 | Bgee | endothelial cell | 1.00 | infobox |
| FRS2 | Bgee | ventricular zone | 1.00 | infobox |
| FRS2 | Bgee | testicle | 1.00 | infobox |
| FRS2 | Bgee | epithelium of colon | 1.00 | infobox |
| FRS2 | Bgee | gonad | 1.00 | infobox |
| FRS2 | Bgee | ganglionic eminence | 1.00 | infobox |
| FRS2 | Bgee | islet of Langerhans | 1.00 | infobox |
| FRS2 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| FRS2 | Bgee | C1 segment | 1.00 | infobox |
| FRS2 | BioGPS | More reference expression data | 1.00 | infobox |
| FRS2 | Chr. | Chromosome 12 (human) | 1.00 | infobox |
| FRS2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| FRS2 | End | 69,579,793 bp | 1.00 | infobox |
| FRS2 | Ensembl | ENSG00000166225 | 1.00 | infobox |
| FRS2 | Entrez | 10818 | 1.00 | infobox |
| FRS2 | External IDs | OMIM: 607743; MGI: 1100860; GeneCards: FRS2 | 1.00 | infobox |
| FRS2 | Gene location (Human) | Gene location (Human)Chr.Chromosome 12 (human)Band12q15Start69,470,349 bpEnd69,579,793 bp | 1.00 | infobox |
| FRS2 | Gene ontology | transmembrane receptor protein tyrosine kinase adaptor activity | 1.00 | infobox |
| FRS2 | Gene ontology | fibroblast growth factor receptor binding | 1.00 | infobox |
| FRS2 | Gene ontology | neurotrophin TRKA receptor binding | 1.00 | infobox |
| FRS2 | Gene ontology | protein binding | 1.00 | infobox |
| FRS2 | Gene ontology | phosphatase activator activity | 1.00 | infobox |
| FRS2 | Gene ontology | 1-phosphatidylinositol-3-kinase activity | 1.00 | infobox |
| FRS2 | Gene ontology | phosphatidylinositol-4,5-bisphosphate 3-kinase activity | 1.00 | infobox |
| FRS2 | Gene ontology | cytoplasm | 1.00 | infobox |
| FRS2 | Gene ontology | endosome | 1.00 | infobox |
The concept neighborhoods around FRS2 bring nearby vocabulary together. In this analysis, examples include Receptor, Gene and Growth. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For FRS2, one of the stronger structural bridges in this analysis connects FRS2 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around FRS2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — FRS2 · EN edition · Analysis: TopicsToTalkAbout