FRS2

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Explore the main themes, entities and connections around FRS2. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Interactions

Interact CBL FGFR1 GRB2 PRKCI

9 related topics

Overview

Protein Gene Signal transducing adaptor protein Receptor Tyrosine Kinases MAPK/ERK

7 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: FRS2, FRS2A, FRS2alpha, SNT, SNT-1, SNT1, FRS1A, fibroblast growth factor receptor substrate 2
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1XR0, 2MFQ
Band: 12q15
Bgee: Achilles tendon · endothelial cell · ventricular zone · testicle · epithelium of colon
BioGPS: More reference expression data
Chr.: Chromosome 12 (human)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Protein
Gene
Signal transducing adaptor protein
Receptor Tyrosine Kinases Receptor Tyrosine Kinase
MAPK/ERK MAPK/ERK pathway
PI3K/AKT/mTOR PI3K/AKT/mTOR pathway
PLCγ Phospholipase C

Interactions

Interact Protein-protein interaction
CBL CBL (gene)
FGFR1 Fibroblast growth factor receptor 1
GRB2
PRKCI
PTPN11
SOS1
TrkA
ALK Anaplastic lymphoma kinase

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes19

Edges18

Triples80

Avg. degree1.89

Density0.105263

Components1

How this topic connects Entity context

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FRS2

Top relations

Gene ontology · 39

FRS2 → 1-phosphatidylinositol-3-kinase activity, anterior/posterior axis specification, embryo, axon guidance, cell-cell junction, cytoplasm, cytosol, endomembrane system, endosome, fibroblast growth factor receptor binding, fibroblast growth factor receptor signaling pathway, forebrain development, G protein-coupled receptor signaling pathway, gastrulation with mouth forming second, integral component of plasma membrane, lens development in camera-type eye, lens fiber cell development, lens placode formation involved in camera-type eye formation, MAPK cascade, membrane, negative regulation of cardiac muscle cell differentiation

Bgee · 10

FRS2 → Achilles tendon, C1 segment, endothelial cell, epithelium of colon, ganglionic eminence, gonad, islet of Langerhans, stromal cell of endometrium, testicle, ventricular zone

RNA expression pattern · 10

FRS2 → Achilles tendon, C1 segment, endothelial cell, epithelium of colon, ganglionic eminence, gonad, islet of Langerhans, stromal cell of endometrium, testicle, ventricular zone

Aliases · 1

FRS2 → FRS2, FRS2A, FRS2alpha, SNT, SNT-1, SNT1, FRS1A, fibroblast growth factor receptor substrate 2

Available structures · 1

FRS2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1XR0, 2MFQ

Band · 1

FRS2 → 12q15

BioGPS · 1

FRS2 → More reference expression data

Chr. · 1

FRS2 → Chromosome 12 (human)

Databases · 1

FRS2 → NCBI: entry; OMA: entry

End · 1

FRS2 → 69,579,793 bp

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

receptor protein human bp gene fibroblast growth factor chr chromosome 12 band substrate adaptor tyrosine signaling mapk prostate search location

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
FRS2	Aliases	FRS2, FRS2A, FRS2alpha, SNT, SNT-1, SNT1, FRS1A, fibroblast growth factor receptor substrate 2	1.00	infobox
FRS2	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1XR0, 2MFQ	1.00	infobox
FRS2	Band	12q15	1.00	infobox
FRS2	Bgee	Achilles tendon	1.00	infobox
FRS2	Bgee	endothelial cell	1.00	infobox
FRS2	Bgee	ventricular zone	1.00	infobox
FRS2	Bgee	testicle	1.00	infobox
FRS2	Bgee	epithelium of colon	1.00	infobox
FRS2	Bgee	gonad	1.00	infobox
FRS2	Bgee	ganglionic eminence	1.00	infobox
FRS2	Bgee	islet of Langerhans	1.00	infobox
FRS2	Bgee	stromal cell of endometrium	1.00	infobox
FRS2	Bgee	C1 segment	1.00	infobox
FRS2	BioGPS	More reference expression data	1.00	infobox
FRS2	Chr.	Chromosome 12 (human)	1.00	infobox
FRS2	Databases	NCBI: entry; OMA: entry	1.00	infobox
FRS2	End	69,579,793 bp	1.00	infobox
FRS2	Ensembl	ENSG00000166225	1.00	infobox
FRS2	Entrez	10818	1.00	infobox
FRS2	External IDs	OMIM: 607743; MGI: 1100860; GeneCards: FRS2	1.00	infobox
FRS2	Gene location (Human)	Gene location (Human)Chr.Chromosome 12 (human)Band12q15Start69,470,349 bpEnd69,579,793 bp	1.00	infobox
FRS2	Gene ontology	transmembrane receptor protein tyrosine kinase adaptor activity	1.00	infobox
FRS2	Gene ontology	fibroblast growth factor receptor binding	1.00	infobox
FRS2	Gene ontology	neurotrophin TRKA receptor binding	1.00	infobox
FRS2	Gene ontology	protein binding	1.00	infobox
FRS2	Gene ontology	phosphatase activator activity	1.00	infobox
FRS2	Gene ontology	1-phosphatidylinositol-3-kinase activity	1.00	infobox
FRS2	Gene ontology	phosphatidylinositol-4,5-bisphosphate 3-kinase activity	1.00	infobox
FRS2	Gene ontology	cytoplasm	1.00	infobox
FRS2	Gene ontology	endosome	1.00	infobox

Related concept clusters Concept neighborhoods

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Connections between topic areas Semantic bridges

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