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SH2B adapter protein 1 is a protein that in humans is encoded by the SH2B1 gene.
The analysis highlights Interactions, Clinical significance and Overview as prominent areas in the source structure around SH2B1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around SH2B1 shows recurring relationship patterns in the source. For example, SH2B1 → ankle, anterior pituitary, apex of heart, granulocyte, left lobe of thyroid gland, left ovary, lip, molar, mucosa of transverse colon, muscle of thigh, neural layer of retina, primary visual cortex, quadriceps femoris muscle, right frontal lobe, right hemisphere of cerebellum, right lobe of thyroid gland, right ovary, right uterine tube, superior frontal gyrus, thymus Another extracted example is SH2B1 → blood coagulation, cytoplasm, cytosol, intracellular signal transduction, lamellipodium assembly, membrane, nucleus, plasma membrane, positive regulation of mitotic nuclear division, positive regulation of signal transduction, protein binding, regulation of DNA biosynthetic process, signal transduction, signaling adaptor activity, transmembrane receptor protein tyrosine kinase adaptor activity, transmembrane receptor protein tyrosine kinase signaling pathway. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp gene chr human band chromosome 16 protein location obesity mouse sh2b adaptor search 874 212 end 28 f3 69
TTTA extracted 85 structured relationships around SH2B1. Examples in this analysis include SH2B1 → Aliases → SH2B1, PSM, SH2B, SH2B adaptor protein 1 and SH2B1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2HDV, 2HDX. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| SH2B1 | Aliases | SH2B1, PSM, SH2B, SH2B adaptor protein 1 | 1.00 | infobox |
| SH2B1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2HDV, 2HDX | 1.00 | infobox |
| SH2B1 | Band | 16p11.2 | 1.00 | infobox |
| SH2B1 | Band | 7 F3|7 69.06 cM | 1.00 | infobox |
| SH2B1 | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| SH2B1 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| SH2B1 | Bgee | right lobe of thyroid gland | 1.00 | infobox |
| SH2B1 | Bgee | right uterine tube | 1.00 | infobox |
| SH2B1 | Bgee | apex of heart | 1.00 | infobox |
| SH2B1 | Bgee | left lobe of thyroid gland | 1.00 | infobox |
| SH2B1 | Bgee | anterior pituitary | 1.00 | infobox |
| SH2B1 | Bgee | right ovary | 1.00 | infobox |
| SH2B1 | Bgee | left ovary | 1.00 | infobox |
| SH2B1 | Bgee | right frontal lobe | 1.00 | infobox |
| SH2B1 | Bgee | neural layer of retina | 1.00 | infobox |
| SH2B1 | Bgee | granulocyte | 1.00 | infobox |
| SH2B1 | Bgee | muscle of thigh | 1.00 | infobox |
| SH2B1 | Bgee | molar | 1.00 | infobox |
| SH2B1 | Bgee | lip | 1.00 | infobox |
| SH2B1 | Bgee | superior frontal gyrus | 1.00 | infobox |
| SH2B1 | Bgee | primary visual cortex | 1.00 | infobox |
| SH2B1 | Bgee | thymus | 1.00 | infobox |
| SH2B1 | Bgee | ankle | 1.00 | infobox |
| SH2B1 | Bgee | quadriceps femoris muscle | 1.00 | infobox |
| SH2B1 | BioGPS | More reference expression data | 1.00 | infobox |
| SH2B1 | Chr. | Chromosome 16 (human) | 1.00 | infobox |
| SH2B1 | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| SH2B1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| SH2B1 | End | 28,874,212 bp | 1.00 | infobox |
| SH2B1 | End | 126,074,596 bp | 1.00 | infobox |
The concept neighborhoods around SH2B1 bring nearby vocabulary together. In this analysis, examples include Search, Location and Obesity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For SH2B1, one of the stronger structural bridges in this analysis connects SH2B1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around SH2B1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Clinical significance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — SH2B1 · EN edition · Analysis: TopicsToTalkAbout