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SH2B1

SH2B adapter protein 1 is a protein that in humans is encoded by the SH2B1 gene.

Interactions, Clinical significance & Overview

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Interactions

5 related topics

Clinical significance

2 related topics

Overview

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Key facts & relationships

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Aliases
SH2B1, PSM, SH2B, SH2B adaptor protein 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2HDV, 2HDX
Band
16p11.2 · 7 F3|7 69.06 cM
Bgee
right hemisphere of cerebellum · mucosa of transverse colon · right lobe of thyroid gland · right uterine tube · apex of heart
BioGPS
More reference expression data
Chr.
Chromosome 16 (human) · Chromosome 7 (mouse)

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Overview

Interactions

Clinical significance

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Map overview Semantic statistics

SH2B1

Nodes13
Edges12
Triples85
Avg. degree1.85
Density0.153846
Components1

How this topic connects Entity context

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SH2B1

Top relations

Bgee · 20
SH2B1 → ankle, anterior pituitary, apex of heart, granulocyte, left lobe of thyroid gland, left ovary, lip, molar, mucosa of transverse colon, muscle of thigh, neural layer of retina, primary visual cortex, quadriceps femoris muscle, right frontal lobe, right hemisphere of cerebellum, right lobe of thyroid gland, right ovary, right uterine tube, superior frontal gyrus, thymus
RNA expression pattern · 20
SH2B1 → ankle, anterior pituitary, apex of heart, granulocyte, left lobe of thyroid gland, left ovary, lip, molar, mucosa of transverse colon, muscle of thigh, neural layer of retina, primary visual cortex, quadriceps femoris muscle, right frontal lobe, right hemisphere of cerebellum, right lobe of thyroid gland, right ovary, right uterine tube, superior frontal gyrus, thymus
Gene ontology · 16
SH2B1 → blood coagulation, cytoplasm, cytosol, intracellular signal transduction, lamellipodium assembly, membrane, nucleus, plasma membrane, positive regulation of mitotic nuclear division, positive regulation of signal transduction, protein binding, regulation of DNA biosynthetic process, signal transduction, signaling adaptor activity, transmembrane receptor protein tyrosine kinase adaptor activity, transmembrane receptor protein tyrosine kinase signaling pathway
related to Clinical significance · 3
SH2B1 → BMI, Furthermore, Variations
related to Interactions · 3
SH2B1 → Grb2, Insulin, Janus
Band · 2
SH2B1 → 16p11.2, 7 F3|7 69.06 cM
Chr. · 2
SH2B1 → Chromosome 16 (human), Chromosome 7 (mouse)
End · 2
SH2B1 → 126,074,596 bp, 28,874,212 bp
Aliases · 1
SH2B1 → SH2B1, PSM, SH2B, SH2B adaptor protein 1
Available structures · 1
SH2B1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2HDV, 2HDX

Important terminology Word statistics

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Important terminology

bp gene chr human band chromosome 16 protein location obesity mouse sh2b adaptor search 874 212 end 28 f3 69

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SH2B1AliasesSH2B1, PSM, SH2B, SH2B adaptor protein 11.00infobox
SH2B1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2HDV, 2HDX1.00infobox
SH2B1Band16p11.21.00infobox
SH2B1Band7 F3|7 69.06 cM1.00infobox
SH2B1Bgeeright hemisphere of cerebellum1.00infobox
SH2B1Bgeemucosa of transverse colon1.00infobox
SH2B1Bgeeright lobe of thyroid gland1.00infobox
SH2B1Bgeeright uterine tube1.00infobox
SH2B1Bgeeapex of heart1.00infobox
SH2B1Bgeeleft lobe of thyroid gland1.00infobox
SH2B1Bgeeanterior pituitary1.00infobox
SH2B1Bgeeright ovary1.00infobox
SH2B1Bgeeleft ovary1.00infobox
SH2B1Bgeeright frontal lobe1.00infobox
SH2B1Bgeeneural layer of retina1.00infobox
SH2B1Bgeegranulocyte1.00infobox
SH2B1Bgeemuscle of thigh1.00infobox
SH2B1Bgeemolar1.00infobox
SH2B1Bgeelip1.00infobox
SH2B1Bgeesuperior frontal gyrus1.00infobox
SH2B1Bgeeprimary visual cortex1.00infobox
SH2B1Bgeethymus1.00infobox
SH2B1Bgeeankle1.00infobox
SH2B1Bgeequadriceps femoris muscle1.00infobox
SH2B1BioGPSMore reference expression data1.00infobox
SH2B1Chr.Chromosome 16 (human)1.00infobox
SH2B1Chr.Chromosome 7 (mouse)1.00infobox
SH2B1DatabasesNCBI: entry; OMA: entry1.00infobox
SH2B1End28,874,212 bp1.00infobox
SH2B1End126,074,596 bp1.00infobox

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