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TEC (gene)

Tyrosine-protein kinase Tec is a tyrosine kinase that in humans is encoded by the TEC gene. Tec kinase is expressed in hematopoietic, liver, and kidney cells and plays an important role in T-helper cell processes. Tec kinase is the name-giving member of the Tec kinase family, a family of non-receptor protein-tyrosine kinases.

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2.7.10.2
↗
Aliases
TEC, PSCTK4, tec protein tyrosine kinase
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LUL
Band
4p12-p11 · 5 C3.2|5 38.44 cM
Bgee
gonad · bone marrow cell · testicle · skin of leg · skin of abdomen
BioGPS
More reference expression data

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TEC (gene)

Nodes95
Edges94
Triples108
Avg. degree1.98
Density0.021053
Components1

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TEC (gene)

Top relations

Gene ontology · 37
TEC (gene) → adaptive immune response, ATP binding, B cell receptor signaling pathway, cell differentiation, cytokine-mediated signaling pathway, cytoplasm, cytoskeleton, cytosol, extrinsic component of cytoplasmic side of plasma membrane, Fc-epsilon receptor signaling pathway, immune system process, innate immune response, integrin-mediated signaling pathway, intracellular signal transduction, kinase activity, lipid binding, membrane, metal ion binding, non-membrane spanning protein tyrosine kinase activity, nucleotide binding
Bgee · 20
TEC (gene) → blood, bone marrow, bone marrow cell, gonad, granulocyte, iris, left lobe of liver, mesenteric lymph nodes, monocyte, proximal tubule, rectum, right adrenal cortex, right kidney, right lung, right uterine tube, sciatic nerve, skin of abdomen, skin of leg, spleen, testicle
RNA expression pattern · 20
TEC (gene) → blood, bone marrow, bone marrow cell, gonad, granulocyte, iris, left lobe of liver, mesenteric lymph nodes, monocyte, proximal tubule, rectum, right adrenal cortex, right kidney, right lung, right uterine tube, sciatic nerve, skin of abdomen, skin of leg, spleen, testicle
related to Interactions · 6
TEC (gene) → ARHGEF12, CD117, DOK1, GNA12, Janus, TEC
Band · 2
TEC (gene) → 4p12-p11, 5 C3.2|5 38.44 cM
Chr. · 2
TEC (gene) → Chromosome 4 (human), Chromosome 5 (mouse)
End · 2
TEC (gene) → 48,269,838 bp, 73,025,826 bp
2.7.10.2 · 1
TEC (gene) → ↗
Aliases · 1
TEC (gene) → TEC, PSCTK4, tec protein tyrosine kinase
Available structures · 1
TEC (gene) → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LUL

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Important terminology

kinase tec cells btk family tyrosine function domain bp gene kinases human role sh3 signaling expressed chr chromosome band activation

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
TEC (gene)2.7.10.2↗1.00infobox
TEC (gene)AliasesTEC, PSCTK4, tec protein tyrosine kinase1.00infobox
TEC (gene)Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LUL1.00infobox
TEC (gene)Band4p12-p111.00infobox
TEC (gene)Band5 C3.2|5 38.44 cM1.00infobox
TEC (gene)Bgeegonad1.00infobox
TEC (gene)Bgeebone marrow cell1.00infobox
TEC (gene)Bgeetesticle1.00infobox
TEC (gene)Bgeeskin of leg1.00infobox
TEC (gene)Bgeeskin of abdomen1.00infobox
TEC (gene)Bgeemonocyte1.00infobox
TEC (gene)Bgeeright uterine tube1.00infobox
TEC (gene)Bgeerectum1.00infobox
TEC (gene)Bgeeright lung1.00infobox
TEC (gene)Bgeeright adrenal cortex1.00infobox
TEC (gene)Bgeesciatic nerve1.00infobox
TEC (gene)Bgeegranulocyte1.00infobox
TEC (gene)Bgeespleen1.00infobox
TEC (gene)Bgeeleft lobe of liver1.00infobox
TEC (gene)Bgeemesenteric lymph nodes1.00infobox
TEC (gene)Bgeeblood1.00infobox
TEC (gene)Bgeeproximal tubule1.00infobox
TEC (gene)Bgeebone marrow1.00infobox
TEC (gene)Bgeeright kidney1.00infobox
TEC (gene)Bgeeiris1.00infobox
TEC (gene)BioGPSMore reference expression data1.00infobox
TEC (gene)Chr.Chromosome 4 (human)1.00infobox
TEC (gene)Chr.Chromosome 5 (mouse)1.00infobox
TEC (gene)DatabasesNCBI: entry; OMA: entry1.00infobox
TEC (gene)End48,269,838 bp1.00infobox

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