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Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor (mainly found as a chromatin-binding protein) that is activated by the sex hormone estrogen. In humans, ERα is encoded by the gene ESR1 (EStrogen Receptor 1).
Tissue distribution and function, Interactions & Clinical significance
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erα estrogen erko mice receptor uterus reproductive bp gene development function male bone female esr1 chr human band mouse hypothalamus
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Estrogen receptor alpha | Aliases | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1, estrogen receptor 1 | 1.00 | infobox |
| Estrogen receptor alpha | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A52, 1ERE, 1ERR, 1G50, 1GWQ, 1GWR, 1HCP, 1HCQ, 1L2I, 1PCG, 1QKT, 1QKU, 1R5K, 1SJ0, 1UOM, 1X7E, 1X7R, 1XP1,… | 1.00 | infobox |
| Estrogen receptor alpha | Band | 6q25.1-q25.2 | 1.00 | infobox |
| Estrogen receptor alpha | Band | 10 A1|10 2.03 cM | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | cervix epithelium | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | vulva | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | endometrium | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | canal of the cervix | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | right uterine tube | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | ectocervix | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | epithelium of lactiferous gland | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | lactiferous duct | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | body of uterus | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | vagina | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | gastrula | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | vas deferens | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | efferent ductule | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | uterus | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | decidua | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | intercostal muscle | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | triceps brachii muscle | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | sternocleidomastoid muscle | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | lumbar spinal ganglion | 1.00 | infobox |
| Estrogen receptor alpha | Bgee | temporal muscle | 1.00 | infobox |
| Estrogen receptor alpha | BioGPS | n/a | 1.00 | infobox |
| Estrogen receptor alpha | Chr. | Chromosome 6 (human) | 1.00 | infobox |
| Estrogen receptor alpha | Chr. | Chromosome 10 (mouse) | 1.00 | infobox |
| Estrogen receptor alpha | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Estrogen receptor alpha | End | 152,129,619 bp | 1.00 | infobox |
| Estrogen receptor alpha | End | 4,955,614 bp | 1.00 | infobox |
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