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Isoform

In genetics, an isoform is a member of a set of similar products that originate from the same gene; such a set can consist of mRNAs or their resultant proteins. The best-studied isoforms are the protein isoforms, or "protein variants", resulting from differences in the coding DNA sequences (CDS) of their precursor mRNAs. While many perform the same or…

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Map overview Semantic statistics

Isoform

Nodes76
Edges75
Triples78
Avg. degree1.97
Density0.026316
Components1

How this topic connects Entity context

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Isoform

Top relations

related to PTEN · 14
Isoform → Also, CDS, DRG, Phosphatase, Pten, Pten J1, Pten J2, PtenJ1, Recent, RNA, So, The, TSS, UTR
related to Promoter usage · 11
Isoform → Cis-regulatory, DNA, For, Other, RNA, So, TF, The, TSS, TSSs, Variable
related to ATF3 · 9
Isoform → Activating, Atf3, CDS, DRG, Four Atf3, However, RAG, These, TSS
related to Alternative splicing · 7
Isoform → Alternative, Because, Consequently, One, RNA, The, Transcript
related to Characteristics · 7
Isoform → Additionally, Because, Generally, However, In, Isoforms, The
related to Glycoform · 7
Isoform → An, Glycoforms, Glycoproteins, NCAM, PSA, These, Typical
related to Types · 7
Isoform → Alternative, Both, In, Isoforms, Structural, The, These
related to Definition · 6
Isoform → AlphaFold, Determining, One, RNAs, The, Three-dimensional
related to Additional studies · 4
Isoform → CNS, RAGs, Recently, RNA-Seq
is a · 1
Isoform → member of a set of similar products that originate from the same gene

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Important terminology

isoforms protein different gene alternative splicing proteins transcript sequence pten also transcription cds rna genes functional sequences promoter usage mrna

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Isoformis amember of a set of similar products that originate from the same gene0.90text
its prevalenceinstance ofone protein isoform is labeled as the canonical sequence based on criteria0.80text
similarity to orthologousinstance ofone protein isoform is labeled as the canonical sequence based on criteria0.80text
Isoformrelated to Additional studiesRecently0.60section
Isoformrelated to Additional studiesRAGs0.60section
Isoformrelated to Additional studiesRNA-Seq0.60section
Isoformrelated to Additional studiesCNS0.60section
Isoformrelated to Alternative splicingAlternative0.60section
Isoformrelated to Alternative splicingThe0.60section
Isoformrelated to Alternative splicingRNA0.60section
Isoformrelated to Alternative splicingBecause0.60section
Isoformrelated to Alternative splicingTranscript0.60section

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